{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T19:23:54Z","timestamp":1782242634978,"version":"3.54.5"},"reference-count":8,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T00:00:00Z","timestamp":1500595200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openrespiratorymedicinejournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TORMJ"],"published-print":{"date-parts":[[2017,7,21]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Nasal non-invasive-ventilation (Nasal NIV) is a mode of ventilatory support providing positive pressure to patients via a nasal interface. The RAM Cannula is an oxygen delivery device that can be used as an alternative approach to deliver positive pressure. Together they have been successfully used to provide respiratory support in neonatal in-patient settings.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To describe the outpatient use of Nasal NIV\/RAM Cannula as a feasible alternative for home respiratory support in children with chronic respiratory failure.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We performed a retrospective case series of 18 children (4 months to 19 years old) using the Nasal NIV\/RAM Cannula in the Pediatric Pulmonary Clinic at the McGovern Medical School, UTHealth (2014-16). Consideration for Nasal NIV\/RAM Cannula utilization included: inability to wean-off in-patient respiratory support, comfort for dyspnea, intolerability of conventional mask interfaces and tracheostomy avoidance.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Average age was 7 years. 50% were Caucasian, 38% African-American and 11% Hispanics. Pulmonary disorders included: chest wall weakness (38%), central control abnormalities (33%), obstructive lung disease (16%) and restrictive lung disease (11%). Indications for Nasal NIV\/RAM Cannula initiation included: CPAP\/BPAP masks intolerability (11%), dyspnea secondary to chest wall weakness (38%) and tracheostomy avoidance (50%). Average length of use of Nasal NIV\/RAM Cannula was 8.4 months. Successful implementation of Nasal NIV\/Ram Cannula was 94%. One patient required a tracheostomy following the use of Nasal NIV\/RAM Cannula. Significant decrease in arterial PaCO<jats:sub>2<\/jats:sub> pre and post Nasal NIV\/RAM cannula initiation was notable (p=0.001).<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Outpatient use of Nasal NIV\/RAM Cannula may prove to be a feasible and save treatment alternative for children with chronic respiratory failure, chest wall weakness, dyspnea and traditional nasal\/face mask intolerance to avoid tracheostomy.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874306401711010041","type":"journal-article","created":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T11:10:30Z","timestamp":1500635430000},"page":"41-46","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Use of Nasal Non-Invasive Ventilation with a RAM Cannula in the Outpatient Home Setting"],"prefix":"10.2174","volume":"11","author":[{"given":"Wilfredo","family":"De Jesus Rojas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl L.","family":"Samuels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Traci R.","family":"Gonzales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina E.","family":"McBeth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aravind","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Jon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Mosquera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.jcrc.2015.12.013","volume":"32","author":"Yaman A.","year":"2016","unstructured":"Yaman A, Kendirli T, \u00d6dek \u00c7, et al. \n                    Efficacy of noninvasive mechanical ventilation in prevention of intubation and reintubation in the pediatric intensive care unit. \n                    J Crit Care  \n                    2016; \n                    32\n                    : 175-81.","journal-title":"J. Crit. Care"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"S67","DOI":"10.1038\/jp.2010.99","volume":"30","author":"Ramanathan R.","year":"2010","unstructured":"Ramanathan R. \n                    Nasal respiratory support through the nares: its time has come. \n                    J Perinatol  \n                    2010; \n                    30\n                    : S67-72.","journal-title":"J. Perinatol."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"718","DOI":"10.3109\/14767058.2014.929659","volume":"28","author":"Nzegwu N.I.","year":"2015","unstructured":"Nzegwu NI, Mack T, DellaVentura R, et al. \n                    Systematic use of the RAM nasal cannula in the Yale-New Haven Children\u2019s Hospital Neonatal Intensive Care Unit: a quality improvement project. \n                    J Matern Fetal Neonatal Med  \n                    2015; \n                    28\n                    (6)\n                    : 718-21.","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/jp.2012.1","volume":"32","author":"Ramanathan R.","year":"2012","unstructured":"Ramanathan R, Sekar KC, Rasmussen M, Bhatia J, Soll RF. \n                    Nasal intermittent positive pressure ventilation after surfactant treatment for respiratory distress syndrome in preterm infants <30 weeks\u2019 gestation: a randomized, controlled trial. \n                    J Perinatol  \n                    2012; \n                    32\n                    (5)\n                    : 336-43.","journal-title":"J. Perinatol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"508","DOI":"10.4187\/respcare.03560","volume":"60","author":"Iyer N.P.","year":"2015","unstructured":"Iyer NP, Chatburn R. \n                    Evaluation of a nasal cannula in noninvasive ventilation using a lung simulator. \n                    Respir Care  \n                    2015; \n                    60\n                    (4)\n                    : 508-12.","journal-title":"Respir. Care"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1093\/tropej\/fmv088","volume":"62","author":"Aktas S.","year":"2016","unstructured":"Aktas S, Unal S, Aksu M, et al. \n                    Nasal HFOV with Binasal Cannula Appears Effective and Feasible in ELBW Newborns. \n                    J Trop Pediatr  \n                    2016; \n                    62\n                    (2)\n                    : 165-8.","journal-title":"J. Trop. Pediatr."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s00134-005-2669-2","volume":"31","author":"Fauroux B.","year":"2005","unstructured":"Fauroux B, Lavis JF, Nicot F, et al. \n                    Facial side effects during noninvasive positive pressure ventilation in children. \n                    Intensive Care Med  \n                    2005; \n                    31\n                    (7)\n                    : 965-9.","journal-title":"Intensive Care Med."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1164\/ajrccm.166.8.257c","volume":"166","author":"Villa M.P.","year":"2002","unstructured":"Villa MP, Pagani J, Ambrosio R, Ronchetti R, Bernkopf E. \n                    Mid-face hypoplasia after long-term nasal ventilation. \n                    Am J Respir Crit Care Med  \n                    2002; \n                    166\n                    (8)\n                    : 1142-3.","journal-title":"Am. J. Respir. 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Care Med."}],"container-title":["The Open Respiratory Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-41\/TORMJ-11-41.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-41\/TORMJ-11-41.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-41\/TORMJ-11-41.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T10:36:46Z","timestamp":1555324606000},"score":1,"resource":{"primary":{"URL":"https:\/\/openrespiratorymedicinejournal.com\/VOLUME\/11\/PAGE\/41\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,21]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7,21]]}},"alternative-id":["TORMJ-11-41"],"URL":"https:\/\/doi.org\/10.2174\/1874306401711010041","relation":{},"ISSN":["1874-3064"],"issn-type":[{"value":"1874-3064","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7,21]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2017-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-17","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}