{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:57:07Z","timestamp":1791273427891,"version":"4.1.0"},"reference-count":15,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2014,10,17]],"date-time":"2014-10-17T00:00:00Z","timestamp":1413504000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["openrheumatologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TORJ"],"published-print":{"date-parts":[[2014,10,17]]},"abstract":"<jats:p>This retrospective observational study summarizes the experiences of 820 patients treated with a new Curcuma extract (Flexofytol\u00ae, 4-6 capsules per day), for more than 6 months for various forms of painful osteoarthritis. These experiences were reported by 110 Belgian general practitioners via a questionnaire that included quality-of-life parameters for assessing patient experience. Data were submitted to an independent statistician for analysis. Within the first 6 weeks, Flexofytol\u00ae improved patient pain, articular mobility, and quality of life. Excellent tolerance was reported, and more than half of these patients were able to discontinue analgaesic and anti-inflammatory drugs. Patient satisfaction was confirmed by their decision to maintain Flexofytol\u00ae therapy for more than 6 months. These data must be confirmed with randomized controlled studies. We currently conclude that Flexofytol\u00ae which is based on a new preparation of curcumin, is as a potential neutraceutical for the care of patients complaining of joint problems, with excellent tolerance and rapid benefits for articular mobility, pain, and quality of life.<\/jats:p>","DOI":"10.2174\/1874312901408010077","type":"journal-article","created":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T03:06:25Z","timestamp":1414379185000},"page":"77-81","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["A New Curcuma Extract (Flexofytol\u00ae) in Osteoarthritis: Results from a Belgian Real-Life Experience"],"prefix":"10.2174","volume":"8","author":[{"given":"Thierry","family":"Appelboom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Maes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelin","family":"Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1007\/s00018-008-7452-4","volume":"65","author":"Hatcher H","year":"2008","unstructured":"Hatcher H, Planalp R, Cho J , et al. \n                    Curcumin from ancient medicine to current clinical trials. \n                    Cell Mol Life Sci  \n                    2008; 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