{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:07:05Z","timestamp":1777860425736,"version":"3.51.4"},"reference-count":30,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T00:00:00Z","timestamp":1532995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openrheumatologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TORJ"],"published-print":{"date-parts":[[2018,7,31]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p>To discover the possibility of using microRNA155 (miRNA155) expression level as a biomarker of Beh\u00e7et's Disease (BD) activity or remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Thirty BD patients\u2019 white blood cells (WBCs) miRNA155 expression was measured and compared to WBCs miRNA155 expression in 15 healthy subjects. Assessment of disease activity was done using Beh\u00e7et's Disease Current Activity Form (BDCAF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>miRNA155 expression significantly decreases with the increase of BD activity scored by BDCAF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Increased miRNA155 may be used as a biomarker of BD remission and thus in the disease follow up. There could be a prospect of treating the disease<jats:italic>via<\/jats:italic>microRNA 155 effect enhancement.<\/jats:p><\/jats:sec>","DOI":"10.2174\/1874312901812010115","type":"journal-article","created":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T03:59:52Z","timestamp":1535342392000},"page":"115-122","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["MicroRNA155 Expression in Relation to BDCAF Scored Beh\u00e7et's Disease in an Egyptian Patients' Sample"],"prefix":"10.2174","volume":"12","author":[{"given":"Sally S.","family":"Hassouna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manal Y.","family":"Tayel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalal M.","family":"ElKaffash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M.","family":"Abdelhady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman H.","family":"Elsayed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","volume":"341","author":"Sakane T.","year":"1999","unstructured":"Sakane T, Takeno M, Suzuki N, Inaba G. 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