{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T22:11:28Z","timestamp":1648591888915},"reference-count":10,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openrheumatologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TORJ"],"published-print":{"date-parts":[[2018,8,29]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Aseptic osteonecrosis of the hip is a clinical entity in which the necrotic process of the bone leads to pain and progressive disability.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Pamidronate seems to reduce drastically the activation of the osteoclasts so that it can be useful only in the early stage of the disease, delaying the time of bone collapsing.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A 27-years-old male was treated with pamidronate for three consecutive days every four weeks.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>After three months the patient came back at control showing a marked improvement in clinical condition, referred full recover from pain and dysmotility with improvement of the quality of life, which was confirmed by the result of MRI he had for control.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We reported a case of aseptic osteonecrosis of the hip which was successfully treated pamidronate at dosage of 45 mg.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874312901812010125","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T05:55:49Z","timestamp":1535608549000},"page":"125-128","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pamidronate Treatment of Osteonecrosis of the Hip in Young Male"],"prefix":"10.2174","volume":"12","author":[{"given":"A.","family":"Lo Gullo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Talotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Atteritano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.2169\/internalmedicine.47.1038","volume":"47","author":"Yildiz N.","year":"2008","unstructured":"Yildiz N, Ardic F, Deniz S. \n                    Very early onset steroid-induced avascular necrosis of the hip and knee in a patient with idiopathic thrombocytopenic purpura. \n                    Intern Med  \n                    2008; \n                    47\n                    (22)\n                    : 1989-92.","journal-title":"Intern. 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Surg."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1097\/BOT.0b013e31815aba30","volume":"22","author":"Abbas A.A.","year":"2008","unstructured":"Abbas AA, Yoon TR, Lee JH, Hur CI. \n                    Posttraumatic avascular necrosis of the femoral head in teenagers treated by a modified transtrochanteric rotational osteotomy: A report of three cases. \n                    J Orthop Trauma  \n                    2008; \n                    22\n                    (1)\n                    : 63-9.","journal-title":"J. Orthop. Trauma"},{"key":"ref4","first-page":"351","volume":"33","author":"Lee M.S.","year":"2010","unstructured":"Lee MS, Hsieh PH, Shih CH, Wang CJ. \n                    Non-traumatic osteonecrosis of the femoral head - from clinical to bench. \n                    Chang Gung Med J  \n                    2010; \n                    33\n                    (4)\n                    : 351-60.","journal-title":"Chang Gung Med. J."},{"key":"ref5","first-page":"273","year":"2006","unstructured":"Sugano N, Miki H, hashimoto J, Yoshikawa H. Does alendronate prevent collapse in osteonecrosis of the femoral head? \n                    Clin Orthop Relat Res  \n                    2006; \n                    (443): \n                    273-9.","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"716538","DOI":"10.1155\/2014\/716538","volume":"2014","author":"Hong Y.C.","year":"2014","unstructured":"Hong YC, Luo RB, Lin T, Zhong HM, Shi JB. \n                    Efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic osteonecrosis. \n                    BioMed Res Int  \n                    2014; \n                    2014\n                    : 716538.","journal-title":"BioMed Res. 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Surg."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1515\/JPEM.2006.19.2.161","volume":"19","author":"Nguyen T.","year":"2006","unstructured":"Nguyen T, Zacharin MR. \n                    Pamidronate treatment of steroid associated osteonecrosis in young patients treated for acute lymphoblastic leukaemia-two-year outcomes. \n                    J Pediatr Endocrinol Metab  \n                    2006; \n                    19\n                    (2)\n                    : 161-7.","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"ref10","first-page":"13","volume":"19","author":"Van Offel J.F.","year":"2001","unstructured":"Van Offel JF, Schuerwegh AJ, Bridts CH, Bracke PG, Stevens WJ, De Clerck LS. \n                    Influence of cyclic intravenous pamidronate on proinflammatory monocytic cytokine profiles and bone density in rheumatoid arthritis treated with low dose prednisolone and methotrexate. \n                    Clin Exp Rheumatol  \n                    2001; \n                    19\n                    (1)\n                    : 13-20.","journal-title":"Clin. Exp. Rheumatol."}],"container-title":["The Open Rheumatology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openrheumatologyjournal.com\/contents\/volumes\/V12\/TORJ-12-125\/TORJ-12-125.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrheumatologyjournal.com\/contents\/volumes\/V12\/TORJ-12-125\/TORJ-12-125.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrheumatologyjournal.com\/contents\/volumes\/V12\/TORJ-12-125\/TORJ-12-125.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T07:32:29Z","timestamp":1555313549000},"score":1,"resource":{"primary":{"URL":"https:\/\/openrheumatologyjournal.com\/VOLUME\/12\/PAGE\/125\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,8,29]]}},"alternative-id":["TORJ-12-125"],"URL":"https:\/\/doi.org\/10.2174\/1874312901812010125","relation":{},"ISSN":["1874-3129"],"issn-type":[{"value":"1874-3129","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,29]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2018-5-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-6-28","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-7-4","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}