{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:17:47Z","timestamp":1761110267044},"reference-count":10,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2016,12,30]],"date-time":"2016-12-30T00:00:00Z","timestamp":1483056000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openorthopaedicsjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOORTHJ"],"published-print":{"date-parts":[[2016,12,30]]},"abstract":"<jats:p>Elderly onset Rheumatoid arthritis (EORA) has important clinical distinctions when compared with younger onset RA (YORA). In knee arthritis of elderly patients, infection, crystal-induced arthritis or EORA should be suspected if elevation of CRP in the preoperative examination and turbid joint effusion in their knee joint are found. Furthermore, if joint swelling and effusion remain after performing total knee arthroplasty (TKA), the infection after TKA, implant debris-related arthritis and EORA should be considered. However, it is difficult to diagnose patients as EORA if Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA) are negative. The differential diagnosis is very important.<\/jats:p>","DOI":"10.2174\/1874325001610010793","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T04:47:07Z","timestamp":1483591627000},"page":"793-796","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Knee Arthritis Without Other Joint Symptoms in the Elderly With Seronegative Elderly Onset Rheumatoid Arthritis"],"prefix":"10.2174","volume":"10","author":[{"given":"Takatomo","family":"Mine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Ihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryutaro","family":"Kuriyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Date","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1136\/ard.2003.015172","volume":"63","author":"Wick M.C.","year":"2004","unstructured":"Wick MC, Lindblad S, Klareskog L, Van Vollenhoven RF. \n                    Relationship between inflammation and joint destruction in early rheumatoid arthritis: a mathematical description. \n                    Ann Rheum Dis  \n                    2004; \n                    63\n                    (7)\n                    : 848-52.","journal-title":"Ann. Rheum. Dis."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1002\/art.20350","volume":"50","author":"Welsing P.M.","year":"2004","unstructured":"Welsing PM, Landew\u00e9 RB, van Riel PL, et al. \n                    The relationship between disease activity and radiologic progression in patients with rheumatoid arthritis: a longitudinal analysis. \n                    Arthritis Rheum  \n                    2004; \n                    50\n                    (7)\n                    : 2082-93.","journal-title":"Arthritis Rheum."},{"key":"ref3","unstructured":"Lipsky PE. \n                    Rheumatoid Arthritis. In: \n                    Harrison\u2019s principles of Intermedicine.  14th ed. \n                    New York: Mc Graw Hill 1998."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1002\/art.10897","volume":"48","author":"Rasch E.K.","year":"2003","unstructured":"Rasch EK, Hirsch R, Paulose-Ram R, Hochberg MC. \n                    Prevalence of rheumatoid arthritis in persons 60 years of age and older in the United States: effect of different methods of case classification. \n                    Arthritis Rheum  \n                    2003; \n                    48\n                    (4)\n                    : 917-26.","journal-title":"Arthritis Rheum."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1002\/art.1780280905","volume":"28","author":"Deal C.L.","year":"1985","unstructured":"Deal CL, Meenan RF, Goldenberg DL, et al. \n                    The clinical features of elderly-onset rheumatoid arthritis. A comparison with younger-onset disease of similar duration. \n                    Arthritis Rheum  \n                    1985; \n                    28\n                    (9)\n                    : 987-94.","journal-title":"Arthritis Rheum."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/0049-0172(94)90087-6","volume":"23","author":"van Schaardenburg D.","year":"1994","unstructured":"van Schaardenburg D, Breedveld FC. \n                    Elderly-onset rheumatoid arthritis. \n                    Semin Arthritis Rheum  \n                    1994; \n                    23\n                    (6)\n                    : 367-78.","journal-title":"Semin. Arthritis Rheum."},{"key":"ref7","first-page":"418","volume":"10","author":"Terkeltaub R.","year":"1983","unstructured":"Terkeltaub R, Esdaile J, D\u00e9cary F, Tannenbaum H. \n                    A clinical study of older age rheumatoid arthritis with comparison to a younger onset group. \n                    J Rheumatol  \n                    1983; \n                    10\n                    (3)\n                    : 418-24.","journal-title":"J. Rheumatol."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1002\/art.1780280905","volume":"28","author":"Deal C.L.","year":"1985","unstructured":"Deal CL, Meenan RF, Goldenberg DL, et al. \n                    The clinical features of elderly-onset rheumatoid arthritis. A comparison with younger-onset disease of similar duration. \n                    Arthritis Rheum  \n                    1985; \n                    28\n                    (9)\n                    : 987-94.","journal-title":"Arthritis Rheum."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"40S","DOI":"10.1016\/S0002-9343(97)90007-3","volume":"103","author":"Kavanaugh A.F.","year":"1997","unstructured":"Kavanaugh AF. \n                    Rheumatoid arthritis in the elderly: is it a different disease? \n                    Am J Med  \n                    1997; \n                    103\n                    (6A)\n                    : 40S-8S.","journal-title":"Am. J. Med."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1136\/ard.2005.051144","volume":"65","author":"Tutuncu Z.","year":"2006","unstructured":"Tutuncu Z, Reed G, Kremer J, Kavanaugh A. \n                    Do patients with older-onset rheumatoid arthritis receive less aggressive treatment? \n                    Ann Rheum Dis  \n                    2006; \n                    65\n                    (9)\n                    : 1226-9.","journal-title":"Ann. Rheum. Dis."}],"container-title":["The Open Orthopaedics Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openorthopaedicsjournal.com\/contents\/volumes\/V10\/TOORTHJ-10-793\/TOORTHJ-10-793.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openorthopaedicsjournal.com\/contents\/volumes\/V10\/TOORTHJ-10-793\/TOORTHJ-10-793.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openorthopaedicsjournal.com\/contents\/volumes\/V10\/TOORTHJ-10-793\/TOORTHJ-10-793.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T11:57:37Z","timestamp":1553255857000},"score":1,"resource":{"primary":{"URL":"https:\/\/openorthopaedicsjournal.com\/VOLUME\/10\/PAGE\/793\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,30]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12,30]]}},"alternative-id":["TOORTHJ-10-793"],"URL":"https:\/\/doi.org\/10.2174\/1874325001610010793","relation":{},"ISSN":["1874-3250"],"issn-type":[{"value":"1874-3250","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12,30]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2016-10-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-21","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}