{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:31:23Z","timestamp":1777617083425,"version":"3.51.4"},"reference-count":7,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2008,3,8]],"date-time":"2008-03-08T00:00:00Z","timestamp":1204934400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openophthalmologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOOPHTJ"],"published-print":{"date-parts":[[2008,3,8]]},"abstract":"<jats:p>\n                    We would like to report an interesting case of acute sclerokeratitis following cataract surgery treated with topical use of Cyclosporine-A. A 61-year old woman with a past history of scleritis in her right eye had an uneventful phaco surgery in her right eye for cataract removal\n                    <jats:italic>via<\/jats:italic>\n                    a corneoscleral incision. Eight months after the initial surgery the patient had a sudden decrease in her visual acquity in the right eye with marked inflammatory signs in the sclera and cornea adjacent to the entry-site of the phaco surgery. Initially the patient was treated with systemic corticosteroids but due to serious side effects topical cyclosporine-A was added instead. Five months later the patient has a significant improvement in terms of visual acquity with marked reduction in the inflammatory signs both in sclera and corneal tissue. We think that topical Cyclosporine-A with its potent immunomodulating effects seems to be of benefit in those cases where systemic corticosteroids are contraindicated or have serious side-effects.\n                  <\/jats:p>","DOI":"10.2174\/1874364100802010031","type":"journal-article","created":{"date-parts":[[2008,3,25]],"date-time":"2008-03-25T11:58:03Z","timestamp":1206446283000},"page":"31-33","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute Sclerokeratitis After Cataract Surgery: Treatment with Topical Use of Cyclosporine \u2013 A"],"prefix":"10.2174","volume":"2","author":[{"given":"K","family":"Doulas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Pantazopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Feretis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1136\/bjo.76.1.17","volume":"76","author":"O Donohue E","year":"1992","unstructured":"O Donohue E, Lightman S, Tuft S, Watson P. \n                    Surgically induced necrotizing sclerokeratitis SINS \u2013precipitating factors and response to treatment \n                    Br J Ophthalmol  \n                    1992; \n                    76\n                    : 17-21.","journal-title":"Br J Ophthalmol"},{"key":"refR2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00003226-200204000-00013","volume":"21","author":"Sridhar MS","year":"2002","unstructured":"Sridhar MS, Mansal AK, Rao GN. \n                    Surgical induced necrotizing scleritis after Pterygium excision and conjuctival auto graft \n                    Cornea  \n                    2002; \n                    21\n                    : 305-7.","journal-title":"Cornea"},{"key":"refR3","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1016\/S0161-6420(91)32062-1","volume":"98","author":"Sainz de Maza M","year":"1991","unstructured":"Sainz de Maza M, Foster CS. \n                    Necrotizing scleritis after ocular surgery. A clinicopathologic study \n                    Ophthalmology  \n                    1991; \n                    98\n                    : 1720-6.","journal-title":"Ophthalmology"},{"key":"refR4","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00003226-199807000-00005","volume":"17","author":"Diaz-Valle D","year":"1998","unstructured":"Diaz-Valle D, Castillo JM, Castillo A, Sayagues O, Banares A, Garcia-Sancez J. \n                    Immunologic and clinical evaluation of post-surgical necrotizing sclerocorneal ulceration \n                    Cornea  \n                    1998; \n                    17\n                    : 371-5.","journal-title":"Cornea"},{"key":"refR5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000090010","volume":"38","author":"Seo KY","year":"2006","unstructured":"Seo KY, Lee HK, Kim EK, Lee JH. \n                    Expression of tumour necrosis factor \u2013A and MMP-9 in surgical induces necrotizing scleritis \n                    Ophthalmic Res  \n                    2006; \n                    38\n                    : 66-70.","journal-title":"Ophthalmic Res"},{"key":"refR6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/00003226-199203000-00010","volume":"11","author":"Carlson AN","year":"1992","unstructured":"Carlson AN, Foulks GN, Perfect GR, Kim JH. \n                    Fungal scleritis after cataract surgery \n                    Cornea  \n                    1992; \n                    11\n                    : 151-4.","journal-title":"Cornea"},{"key":"refR7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2165\/00003088-200544030-00003","volume":"44","author":"Tang-Kiu Diane DS","year":"2005","unstructured":"Tang-Kiu Diane DS, Acheampong A. \n                    Ocular pharmacokinetics and safety of Cyclosporine-A. A novel topical treatment for dry-eye \n                    Clin Pharmacokinet  \n                    2005; \n                    44\n                    : 247-61.","journal-title":"Clin Pharmacokinet"}],"container-title":["The Open Ophthalmology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openophthalmologyjournal.com\/contents\/volumes\/V2\/TOOPHTJ-2-31\/TOOPHTJ-2-31.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openophthalmologyjournal.com\/contents\/volumes\/V2\/TOOPHTJ-2-31\/TOOPHTJ-2-31.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openophthalmologyjournal.com\/contents\/volumes\/V2\/TOOPHTJ-2-31\/TOOPHTJ-2-31.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T06:21:01Z","timestamp":1761286861000},"score":1,"resource":{"primary":{"URL":"https:\/\/openophthalmologyjournal.com\/VOLUME\/2\/PAGE\/31\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,8]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,3,8]]}},"alternative-id":["TOOPHTJ-2-31"],"URL":"https:\/\/doi.org\/10.2174\/1874364100802010031","relation":{},"ISSN":["1874-3641"],"issn-type":[{"value":"1874-3641","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3,8]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Double blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2008-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-02-20","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-02-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-03-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}