{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T22:08:33Z","timestamp":1693346913208},"reference-count":6,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["openophthalmologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOOPHTJ"],"published-print":{"date-parts":[[2013,10,31]]},"abstract":"<jats:p>This 47 year old female developed the new onset of a polypoidal subretinal neovascular membrane in the left eye 13 years after having polypoidal choroidal vasculopathy (PCV) treated in the right eye. The indocyanine green (ICG) angiography of the left eye at initial presentation showed a normal choroidal vascular pattern without PCV. The new development of a PCV complex on ICG angiography demonstrates that PCV is truly a type of subretinal neovascularization, and not a choroidal vascular abnormality. The optical coherence tomography shows that the polypoidal vascular complex lies above Bruch\u2019s membrane and beneath the retinal pigment epithelium, and not within the choroid. Treatment with high dose ranibizumab (2.0 mg) resulted in excellent polyp closure and regression of the branching vascular network. The documented new development of polypoidal subretinal vessels on ICG angiography and the response to ranibizumab supports that PCV is a polypoidal neovasculopathy (PNV).<\/jats:p>","DOI":"10.2174\/1874364101307010082","type":"journal-article","created":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T06:23:23Z","timestamp":1384323803000},"page":"82-84","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Polypoidal Choroidal Vasculopathy \u2013 A Type I Polypoidal Subretinal Neovasculopathy"],"prefix":"10.2174","volume":"7","author":[{"given":"Gregg T","family":"Kokame","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00006982-199010010-00001","volume":"10","author":"Yannuzzi LA","year":"1990","unstructured":"Yannuzzi LA, Sorensen J, Spaide RF, Lipson B. \n                    Idiopathic polypoidal choroidal vasculopathy \n                    Retina  \n                    1990; \n                    10\n                    : 1-8.","journal-title":"Retina"},{"key":"refR2","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1001\/archopht.1997.01100150480005","volume":"115","author":"Yannuzzi LA","year":"1997","unstructured":"Yannuzzi LA, Ciardella A, Spaide RF, et al. \n                    The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy \n                    Arch Ophthalmol  \n                    1997; \n                    115\n                    : 478-5.","journal-title":"Arch Ophthalmol"},{"key":"refR3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.preteyeres.2009.10.001","volume":"29","author":"Laude A","year":"2010","unstructured":"Laude A, Cackett PD, Vithana E, et al. \n                    Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: Same or different disease? \n                    Prog Retin Eye Res  \n                    2010; \n                    29\n                    (1)\n                    : 19-29.","journal-title":"Prog Retin Eye Res"},{"key":"refR4","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1097\/IAE.0b013e3181e7976b","volume":"30","author":"Freund KB","year":"2010","unstructured":"Freund KB, Zweifel SA, Engelbert M. \n                    Editorial. Do we need a new\nclassification for choroidal neovascularization in age-related\nmacular degeneration? \n                    Retina  \n                    2010; \n                    30\n                    : 1333-49.","journal-title":"Retina"},{"key":"refR5","unstructured":"Gass JD. \n                    Stereoscopic atlas of macular diseases.  4th Ed. \n                    St\nLouis, Missouri: C. V. 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