{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T18:36:37Z","timestamp":1649097397772},"reference-count":15,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T00:00:00Z","timestamp":1498694400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openophthalmologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOOPHTJ"],"published-print":{"date-parts":[[2017,6,29]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The diagnosis of plus disease in retinopathy of prematurity (ROP) largely determines the need for treatment; however, this diagnosis is subjective. To make the diagnosis of plus disease more objective, semi-automated computer programs (<jats:italic>e.g.<\/jats:italic> ROPtool) have been created to quantify vascular dilation and tortuosity. ROPtool can accurately analyze blood vessels only in images with very good quality, but many still images captured by indirect ophthalmoscopy have insufficient image quality for ROPtool analysis.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the ability of an image fusion methodology (robust mosaicing) to increase the efficiency and traceability of posterior pole vessel analysis by ROPtool.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Materials and Methodology:<\/jats:title>\n                    <jats:p>We retrospectively reviewed video indirect ophthalmoscopy images acquired during routine ROP examinations and selected the best unenhanced still image from the video for each infant. Robust mosaicing was used to create an enhanced mosaic image from the same video for each eye. We evaluated the time required for ROPtool analysis as well as ROPtool\u2019s ability to analyze vessels in enhanced vs. unenhanced images.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We included 39 eyes of 39 infants. ROPtool analysis was faster (125 vs. 152 seconds; <jats:italic>p<\/jats:italic>=0.02) in enhanced vs. unenhanced images, respectively. ROPtool was able to trace retinal vessels in more quadrants (143\/156, 92% vs 115\/156, 74%; p=0.16) in enhanced mosaic vs. unenhanced still images, respectively and in more overall (38\/39, 97% vs. 34\/39, 87%; p=0.07) enhanced mosaic vs. unenhanced still images, respectively.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Retinal image enhancement using robust mosaicing advances efforts to automate grading of posterior pole disease in ROP.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874364101711010143","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T07:03:00Z","timestamp":1498719780000},"page":"143-151","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Using an Image Fusion Methodology to Improve Efficiency and Traceability of Posterior Pole Vessel Analysis by ROPtool"],"prefix":"10.2174","volume":"11","author":[{"given":"Sasapin.G.","family":"Prakalapakorn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura A.","family":"Vickers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolando","family":"Estrada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon F.","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Tomasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sina","family":"Farsiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David K.","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref1","first-page":"1684","volume":"12","year":"2003","unstructured":"Early Treatment For Retinopathy Of Prematurity Cooperative G. Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial. \n                    Arch Ophthalmol  \n                    2003; \n                    12\n                    (121)\n                    : 1684-94.","journal-title":"Arch. Ophthalmol."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.jaapos.2007.11.022","volume":"12","author":"Wallace D.K.","year":"2008","unstructured":"Wallace DK, Quinn GE, Freedman SF, Chiang MF. \n                    Agreement among pediatric ophthalmologists in diagnosing plus and pre-plus disease in retinopathy of prematurity. \n                    J AAPOS  \n                    2008; \n                    12\n                    (4)\n                    : 352-6.","journal-title":"J. AAPOS"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1001\/archopht.125.7.875","volume":"125","author":"Chiang M.F.","year":"2007","unstructured":"Chiang MF, Jiang L, Gelman R, Du YE, Flynn JT. \n                    Interexpert agreement of plus disease diagnosis in retinopathy of prematurity. \n                    Arch Ophthalmol  \n                    2007; \n                    125\n                    (7)\n                    : 875-80.","journal-title":"Arch. Ophthalmol."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/j.ajo.2006.11.024","volume":"143","author":"Johnson K.S.","year":"2007","unstructured":"Johnson KS, Mills MD, Karp KA, Grunwald JE. \n                    Semiautomated analysis of retinal vessel diameter in retinopathy of prematurity patients with and without plus disease. \n                    Am J Ophthalmol  \n                    2007; \n                    143\n                    (4)\n                    : 723-5.","journal-title":"Am. J. Ophthalmol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.jaapos.2007.04.008","volume":"11","author":"Wallace D.K.","year":"2007","unstructured":"Wallace DK, Zhao Z, Freedman SF. \n                    A pilot study using \u201cROPtool\u201d to quantify plus disease in retinopathy of prematurity. \n                    J AAPOS  \n                    2007; \n                    11\n                    (4)\n                    : 381-7.","journal-title":"J. AAPOS"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"3577","DOI":"10.1167\/iovs.07-1353","volume":"49","author":"Wilson C.M.","year":"2008","unstructured":"Wilson CM, Cocker KD, Moseley MJ, et al. \n                    Computerized analysis of retinal vessel width and tortuosity in premature infants. \n                    Invest Ophthalmol Vis Sci  \n                    2008; \n                    49\n                    (8)\n                    : 3577-85.","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"4734","DOI":"10.1167\/iovs.05-0646","volume":"46","author":"Gelman R.","year":"2005","unstructured":"Gelman R, Martinez-Perez ME, Vanderveen DK, Moskowitz A, Fulton AB. \n                    Diagnosis of plus disease in retinopathy of prematurity using Retinal Image multiScale Analysis. \n                    Invest Ophthalmol Vis Sci  \n                    2005; \n                    46\n                    (12)\n                    : 4734-8.","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S1091-8531(02)00015-0","volume":"7","author":"Wallace D.K.","year":"2003","unstructured":"Wallace DK, Jomier J, Aylward SR, Landers MB III. \n                    Computer-automated quantification of plus disease in retinopathy of prematurity. \n                    J AAPOS  \n                    2003; \n                    7\n                    (2)\n                    : 126-30.","journal-title":"J. AAPOS"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1001\/archopht.125.11.1523","volume":"125","author":"Wallace D.K.","year":"2007","unstructured":"Wallace DK, Freedman SF, Zhao Z, Jung SH. \n                    Accuracy of ROPtool vs individual examiners in assessing retinal vascular tortuosity. \n                    Arch Ophthalmol  \n                    2007; \n                    125\n                    (11)\n                    : 1523-30.","journal-title":"Arch. Ophthalmol."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1097\/IAE.0b013e3181803c14","volume":"28","author":"Ahmad S.","year":"2008","unstructured":"Ahmad S, Wallace DK, Freedman SF, Zhao Z. \n                    Computer-assisted assessment of plus disease in retinopathy of prematurity using video indirect ophthalmoscopy images. \n                    Retina  \n                    2008; \n                    28\n                    (10)\n                    : 1458-62.","journal-title":"Retina"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2871","DOI":"10.1364\/BOE.2.002871","volume":"2","author":"Estrada R.","year":"2011","unstructured":"Estrada R, Tomasi C, Cabrera MT, Wallace DK, Freedman SF, Farsiu S. \n                    Enhanced video indirect ophthalmoscopy (VIO) via robust mosaicing. \n                    Biomed Opt Express  \n                    2011; \n                    2\n                    (10)\n                    : 2871-87.","journal-title":"Biomed. Opt. Express"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"542","DOI":"10.3928\/23258160-20141118-09","volume":"45","author":"Cabrera M.T.","year":"2014","unstructured":"Cabrera MT, Freedman SF, Hartnett ME, Stinnett SS, Chen BB, Wallace DK. \n                    Real-time, computer-assisted quantification of plus disease in retinopathy of prematurity at the bedside. \n                    Ophthalmic Surg Lasers Imaging Retina  \n                    2014; \n                    45\n                    (6)\n                    : 542-8.","journal-title":"Ophthalmic Surg. 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