{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:34:03Z","timestamp":1793666043835,"version":"4.5.1"},"reference-count":23,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openophthalmologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOOPHTJ"],"published-print":{"date-parts":[[2018,7,23]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p>Descemet Membrane Endothelial Keratoplasty (DMEK) is now becoming the popular form of endothelial keratoplasty using only donor DM with healthy endothelium as true component lamellar corneal surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To analyze the results of visual outcomes, endothelial cell loss and complications of Descemet membrane endothelial keratoplasty in first consecutive 100 Indian eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>100 eyes of 95 consecutive patients with endothelial dysfunctions of different etiologies scheduled for DMEK, were included in this study. In each case, surgeon prepared tissue using McCarey Kaufman medium- or Cornisol-preserved donor cornea with a cell count of \u22652500 cells\/mm<jats:sup>2<\/jats:sup>. Surgical complications, Best Spectacle Corrected Visual Acuity (BSCVA); Endothelial Cell Density (ECD) and Endothelial Cell Loss (ECL) were analyzed for each patient after a minimum follow-up of three months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The Main indication was pseudophakic corneal edema or bullous keratopathy in 52 (52%) eyes. 38 (38%) eyes had Fuchs\u2032 dystrophy with various grades of cataract. In 43 phakic eyes, DMEK was combined with cataract surgery and intraocular lens implantation. Mean DM-roll preparation time was 7.5 \u00b1 2.8 min and in 3 eyes, DM-graft were damaged. After 3-months, BSCVA was \u226520\/25 in 57 (57.6%) cases. Mean ECD was 2123 \u00b1 438\/mm<jats:sup>2<\/jats:sup>(range: 976 - 3208\/ mm<jats:sup>2<\/jats:sup>) and the mean endothelial cell loss after 3-months was 26.92 \u00b1 13.40 (range: 4.90 - 66.6%). Partial DM detachment occurred in 8 (8.0%) eyes and rebubbling required in 4 eyes. Iatrogenic primary graft failure occurred in one eye.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Descemet membrane endothelial keratoplasty is a safe and effective procedure in several types of endothelial diseases among Indian patients with encouraging surgical and visual outcomes. Complications are less and endothelial cell loss percentage is acceptable.<\/jats:p><\/jats:sec>","DOI":"10.2174\/1874364101812010134","type":"journal-article","created":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T11:04:06Z","timestamp":1532084646000},"page":"134-142","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) Using Surgeon\u2019s Prepared Donor DM-Roll in Consecutive 100 Indian Eyes"],"prefix":"10.2174","volume":"12","author":[{"given":"Samar K","family":"Basak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soham","family":"Basak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viraj R","family":"Pradhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1111\/j.1442-9071.2010.02213.x","volume":"38","author":"Price M.O.","year":"2010","unstructured":"Price MO, Price FW Jr. Endothelial keratoplasty - A review. 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