{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:59:30Z","timestamp":1761746370779,"version":"build-2065373602"},"reference-count":5,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2011,1,18]],"date-time":"2011-01-18T00:00:00Z","timestamp":1295308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openneuroimagingjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TONIJ"],"published-print":{"date-parts":[[2011,1,18]]},"abstract":"<jats:p>We describe a case of schwannomatosis presenting as radicular pain and numbness in multiple radicular nerve distributions. There were multiple peripheral nerve tumors detected by magnetic resonance imaging (MRI) at the left vestibular nerve, cauda equina, right radial nerve, thoracic paraspinal nerve, and brachial plexi. Several resected tumors have features of schwannomas, including hypercellular Antoni A areas, hypocellular Antoni B areas, Verocay bodies, and hyalinized blood vessels. The specimens are also positive for immunohistochemical staining for INI1 with diffuse nuclear staining. The findings are consistent with sporadic form of schwannomatosis. This case highlights the importance of using MRI and INI1 immunohistochemistry to differentiate familial schwannomatosis, neurofibromatosis 2 (NF2)-associated schwannomatosis, and sporadic schwannomatosis.<\/jats:p>","DOI":"10.2174\/1874440001105010009","type":"journal-article","created":{"date-parts":[[2011,2,18]],"date-time":"2011-02-18T01:19:19Z","timestamp":1297991959000},"page":"09-13","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Polyradiculopathies from Schwannomatosis"],"prefix":"10.2174","volume":"05","author":[{"given":"Yuxia","family":"Jia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasini","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Groff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric T","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1200\/JCO.2000.18.15.2926","volume":"18","author":"Wong ET","year":"2000","unstructured":"Wong ET, Joseph JT. \n                    Carcinomatous leptomeningeal metastases \n                    J Clin Oncol  \n                    2000; \n                    18\n                    : 2926-9.","journal-title":"J Clin Oncol"},{"key":"refR2","doi-asserted-by":"publisher","first-page":"3605","DOI":"10.1200\/JCO.2005.01.131","volume":"23","author":"Chamberlain MC","year":"2005","unstructured":"Chamberlain MC. \n                    Neoplastic meningitis \n                    J Clin Oncol  \n                    2005; \n                    23\n                    : 3605-13.","journal-title":"J Clin Oncol"},{"key":"refR3","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/BF02478883","volume":"14","author":"Wakabayashi K","year":"1997","unstructured":"Wakabayashi K, Kawasaki K, Ono K, et al. \n                    Leptomeningeal meningiomatosis with widespread whorl formation \n                    Brain Tumor Pathol  \n                    1997; \n                    14\n                    : 139-43.","journal-title":"Brain Tumor Pathol"},{"key":"refR4","doi-asserted-by":"publisher","first-page":"1838","DOI":"10.1212\/01.WNL.0000163982.78900.AD","volume":"64","author":"MacCollin M","year":"2005","unstructured":"MacCollin M, Chiocca EA, Evans DG, et al. \n                    Diagnostic criteria for schwannomatosis \n                    Neurology  \n                    2005; \n                    64\n                    : 1838-45.","journal-title":"Neurology"},{"key":"refR5","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1750-3639.2008.00155.x","volume":"18","author":"Patil S","year":"2008","unstructured":"Patil S, Perry A, MacCollin M, et al. \n                    Immunohistochemical analysis supports a role for INI1\/SMARCB1 in hereditary forms of schwannomas, but not in solitary, sporadic schwannomas \n                    Brain Pathol  \n                    2008; \n                    18\n                    : 517-9.","journal-title":"Brain Pathol"}],"container-title":["The Open Neuroimaging Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openneuroimagingjournal.com\/contents\/volumes\/V05\/TONIJ-5-9\/TONIJ-5-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openneuroimagingjournal.com\/contents\/volumes\/V05\/TONIJ-5-9\/TONIJ-5-9.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openneuroimagingjournal.com\/contents\/volumes\/V05\/TONIJ-5-9\/TONIJ-5-9.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T11:13:57Z","timestamp":1761736437000},"score":1,"resource":{"primary":{"URL":"https:\/\/openneuroimagingjournal.com\/VOLUME\/05\/PAGE\/09\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,18]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1,18]]}},"alternative-id":["TONIJ-5-9"],"URL":"https:\/\/doi.org\/10.2174\/1874440001105010009","relation":{},"ISSN":["1874-4400"],"issn-type":[{"type":"print","value":"1874-4400"}],"subject":[],"published":{"date-parts":[[2011,1,18]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Double blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2010-8-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-10-18","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-10-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-01-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}