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A stack of scientific documents reflects a huge number of potent plant-based\nanticancer drugs such as curcumin (CUR), podophyllotoxin, camptothecin (CPT), vincristine, vinblastine,\npaclitaxel (PTX), etc. that have been integrated into the modern practice of cancer treatment.\nThe demand for natural products raises exponentially as they are generally considered to be\nsafe, and devoid of critical toxic effects at the therapeutic dose when compared to their synthetic\ncounterparts. Despite rising interest towards the potent phytoconstituents, formulation developer\nfaces various challenges in drug development processes such as poor water solubility, low bioavailability,\nmarginal permeability, and nonspecific drug delivery at the target site, etc. Further, adverse\ndrug reaction and multidrug resistance are other critical issues that need to be addressed.\nNanomedicines owing to their unique structural and functional attributes help to fix the above challenges\nfor improved translational outcomes. This review summarises the prospects and challenges\nof a nanotechnology-based drug delivery approach for the delivery of plant-based anticancer drugs.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1874467213666200525010624","type":"journal-article","created":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T06:14:43Z","timestamp":1590387283000},"page":"292-305","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Recent Advances in Herbal Nanomedicines for Cancer Treatment"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1239-9245","authenticated-orcid":true,"given":"Deepak","family":"Pradhan","sequence":"first","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6055-8928","authenticated-orcid":true,"given":"Prativa","family":"Biswasroy","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7445-6201","authenticated-orcid":true,"given":"Amita","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2052-5723","authenticated-orcid":true,"given":"Dipak K.","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4776-1766","authenticated-orcid":true,"given":"Goutam","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goutam","family":"Rath","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, School of Pharmaceutical Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"Bray F.","year":"2018","unstructured":"Bray F.; Ferlay J.; Soerjomataram I.; Siegel R.L.; Torre L.A.; Jemal A.; Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 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