{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:54:32Z","timestamp":1787766872625,"version":"build-2784847793"},"reference-count":0,"publisher":"Elsevier BV","issue":"6","funder":[{"DOI":"10.13039\/501100006595","name":"Romanian Ministry of Research and Innovation, CNCS -UEFISCDI,","doi-asserted-by":"publisher","award":["PN-III-P1-1.1-PD-2016-1900"],"award-info":[{"award-number":["PN-III-P1-1.1-PD-2016-1900"]}],"id":[{"id":"10.13039\/501100006595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003336","name":"Bulgarian National Science Fund","doi-asserted-by":"publisher","award":["KP-06-OPR 03\/8"],"award-info":[{"award-number":["KP-06-OPR 03\/8"]}],"id":[{"id":"10.13039\/501100003336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004755","name":"Internal Grant Agency of UVPS Brno","doi-asserted-by":"publisher","award":["310\/2019\/FaF"],"award-info":[{"award-number":["310\/2019\/FaF"]}],"id":[{"id":"10.13039\/501100004755","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CMP"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>Substances present in nature have been a continuous source for the development of drugs for\ncardiovascular and infectious diseases, cancer, and many other diseases. As the literature concerning these natural\nproducts grows, it becomes more difficult for a reader to quickly grasp the essential facts and develop a well-informed\nimpression of this field of research. Until now, it has also been difficult to determine which natural products and research\nobjectives were receiving the most attention as measured by number of citations.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Objective:<\/jats:title>\n<jats:p>The current study of all published articles concerned with natural products sought to identify which natural\nproducts and which research objectives are connected with the major contributors to scientific journals based on the\nnumber of relevant publications and the number of times each publication was cited elsewhere.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p> Bibliometric data, including citation data, were extracted from the Web of Science database using the search\nstring TS=(\u201cnatural product*)\u201d and analyzed by the VOSviewer software.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p> The search yielded 63,194 articles, with more than half of the manuscripts published since 2012. The ratio of\noriginal articles to reviews was 5.8:1. The major contributing countries were the United States, China, Germany, Japan, and India. Articles were published mainly in journals focused on chemistry, pharmacology or biochemistry. Curcumin,\nresveratrol, and terpenoids were the most frequently cited natural products.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p> The results of the current study provide researchers from different backgrounds and healthcare professionals\nwith a brief overview of the major trends in natural-product research in the form of a citation-based summary of the\nrelevant literature.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1874467213666201214124327","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T11:02:07Z","timestamp":1608030127000},"page":"993-1002","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Natural Products, the Continuous Source of Therapeutic Molecules for Various Diseases: Literature Landscape Analysis"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3672-357X","authenticated-orcid":true,"given":"Andy W.K.","family":"Yeung","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong S.A.R.,China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5848-8457","authenticated-orcid":true,"given":"Andrei","family":"Mocan","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, \u201cIuliu Ha\u0163ieganu\u201d University of Medicine and Pharmacy, 23 Ghe. Marinescu Street, 400337 Cluj-Napoca,Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-0481","authenticated-orcid":true,"given":"Nikolay T.","family":"Tzvetkov","sequence":"additional","affiliation":[{"name":"Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology \u201cRoumen Tsanev\u201d, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 21, 1113 Sofia,Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4336-7924","authenticated-orcid":true,"given":"Karel","family":"\u0160mejkal","sequence":"additional","affiliation":[{"name":"Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, Palack\u00e9ho 1946\/1, 61200 Brno,Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7618-5505","authenticated-orcid":true,"given":"Elke H.","family":"Heiss","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, 1090 Vienna,Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2545-0967","authenticated-orcid":true,"given":"Atanas G.","family":"Atanasov","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, 1090 Vienna,Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","container-title":["Current Molecular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/eurekaselect.com\/article\/download\/189116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.eurekaselect.com\/189116\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/eurekaselect.com\/article\/download\/189116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T22:57:13Z","timestamp":1746572233000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.eurekaselect.com\/189116\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1874467213666201214124327","relation":{},"ISSN":["1874-4672"],"issn-type":[{"value":"1874-4672","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2019-04-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-04","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}