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Recent works have shown that cell-miRNAs can modulate antiviral defense during viral infection, and viruses can disrupt these existing miRNA networks. Furthermore, multiple RNA viruses encode their own miRNAs to evade the host immune response. In this review, we analyze the activities of both, miRNAs as pro-viral modulators and miRNAs as anti-viral agents and their relationship with the development of the disease.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/2211536611666220816124650","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T11:09:55Z","timestamp":1660734595000},"page":"185-189","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tiny Regulators in Viral Infection: Carving SARS-CoV-2 by miRNAs"],"prefix":"10.2174","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7147-9635","authenticated-orcid":true,"given":"Natalia","family":"Mart\u00ednez-Acu\u00f1a","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine, School of Medicine, Autonomous University of Nuevo Leon,\nMonterrey 64460, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6690-7428","authenticated-orcid":true,"given":"Sonia Amelia","family":"Lozano-Sep\u00falveda","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine, School of Medicine, Autonomous University of Nuevo Leon,\nMonterrey 64460, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"del Carmen Mart\u00ednez-Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias B\u00e1sicas, Instituto Tecnol\u00f3gico de Tl\u00e1huac II, Tecnol\u00f3gico Nacional\nde M\u00e9xico, Mexico City 13550, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2311-2534","authenticated-orcid":true,"given":"Ana Mar\u00eda","family":"Rivas-Estilla","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine, School of Medicine, Autonomous University of Nuevo Leon,\nMonterrey 64460, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/biology10090829","volume":"10","author":"Palermo E.","year":"2021","unstructured":"Palermo E.; Di Carlo D.; Sgarbanti M.; Hiscott J.; Type I interferons in covid-19 pathogenesis. 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