{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:19:40Z","timestamp":1773213580706,"version":"3.50.1"},"reference-count":190,"publisher":"Bentham Science Publishers Ltd.","issue":"3","funder":[{"DOI":"10.13039\/501100001871","name":"FCT","doi-asserted-by":"publisher","award":["UID\/CTM\/50011\/2019"],"award-info":[{"award-number":["UID\/CTM\/50011\/2019"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["PTDC\/BBB-BQB\/1368\/2014)"],"award-info":[{"award-number":["PTDC\/BBB-BQB\/1368\/2014)"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["(PTDC\/MEC-AND\/28691\/2017"],"award-info":[{"award-number":["(PTDC\/MEC-AND\/28691\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["IFCT2015"],"award-info":[{"award-number":["IFCT2015"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["PTDC\/BIM-MET\/4712\/2014"],"award-info":[{"award-number":["PTDC\/BIM-MET\/4712\/2014"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["PTDC\/MEC-AND\/28691\/2017"],"award-info":[{"award-number":["PTDC\/MEC-AND\/28691\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["IFCT2015"],"award-info":[{"award-number":["IFCT2015"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technology","doi-asserted-by":"publisher","award":["PTDC\/BBB-BQB\/1368\/2014)"],"award-info":[{"award-number":["PTDC\/BBB-BQB\/1368\/2014)"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CMC"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n<jats:title\/>\n<jats:p>The prevalence of obesity has tripled in recent decades and is now considered an alarming\npublic health problem. In recent years, a group of endocrine disruptors, known as obesogens, have\nbeen directly linked to the obesity epidemic. Its etiology is generally associated with a sedentary\nlifestyle, a high-fat diet and genetic predisposition, but environmental factors, such as obesogens,\nhave also been reported as contributors for this pathology. In brief, obesogens are exogenous chemical\ncompounds that alter metabolic processes and\/or energy balance and appetite, thus predisposing\nto weight gain. Although this theory is still recent, the number of compounds with suspected obesogenic\nactivity has steadily increased over the years, though many of them remain a matter of debate.\nTechnical-grade chlordane is an organochlorine pesticide widely present in the environment,\nalbeit at low concentrations. Highly lipophilic compounds can be metabolized by humans and animals\ninto more toxic and stable compounds that are stored in fat tissue and consequently pose a danger\nto the human body, including the physiology of adipose tissue, which plays an important role in\nweight regulation. In addition, technical-grade chlordane is classified as a persistent organic pollutant,\na group of chemicals whose epidemiological studies are associated with metabolic disorders,\nincluding obesity. Herein, we discuss the emerging roles of obesogens as threats to public health. We\nparticularly discuss the relevance of chlordane persistence in the environment and how its effects on\nhuman and animal health provide evidence for its role as an endocrine disruptor with possible obesogenic\nactivity.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0929867327666200121122208","type":"journal-article","created":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T12:01:33Z","timestamp":1579694493000},"page":"548-568","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Is Technical-Grade Chlordane an Obesogen?"],"prefix":"10.2174","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-3473","authenticated-orcid":true,"given":"Juliana F.","family":"Silva","sequence":"first","affiliation":[{"name":"Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, P.O. Box 4050-313, Porto,Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8584-4979","authenticated-orcid":true,"given":"Bruno P.","family":"Moreira","sequence":"additional","affiliation":[{"name":"Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, P.O. Box 4050-313, Porto,Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7796-2051","authenticated-orcid":true,"given":"Lu\u00eds","family":"Rato","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilha,Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6703-7869","authenticated-orcid":true,"given":"Maria","family":"de Lourdes Pereira","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences &amp; CICECO - Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro,Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4989-5699","authenticated-orcid":true,"given":"Pedro F.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, P.O. Box 4050-313, Porto,Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7635-783X","authenticated-orcid":true,"given":"Marco G.","family":"Alves","sequence":"additional","affiliation":[{"name":"Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, P.O. Box 4050-313, Porto,Portugal"}]}],"member":"965","reference":[{"key":"ref=1","year":"2017","unstructured":"Obesity W.H.O.Available at:  ext-link-type=\"uri\"\n                xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.who.int\/topics\/obesity\/en\/\">http:\/\/www.who.int\/topics\/obesity\/en\/(Accessed: 5 December, 2017)2017"},{"key":"ref=2","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s11892-017-0966-0","volume":"17","author":"Yang C.","year":"2017","unstructured":"Yang C.; Kong A.P.S.; Cai Z.; Chung A.C.K.; Persistent organic pollutants as risk factors for obesity and diabetes. Curr Diab Rep 2017,17(12),132","journal-title":"Curr Diab Rep"},{"key":"ref=3","year":"2018","unstructured":"W.H.O. Obesity and Overweight Available at:  ext-link-type=\"uri\"\n                xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesityandoverweight\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesityandoverweight(Accessed: 10 December, 2017)2018"},{"key":"ref=4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-3459","volume":"141","author":"Skinner A.C.","year":"2018","unstructured":"Skinner A.C.; Ravanbakht S.N.; Skelton J.A.; Perrin E.M.; Armstrong S.C.; Prevalence of obesity and severe obesity in US children, 1999-2016. Pediatrics 2018,141(3)","journal-title":"Pediatrics"},{"key":"ref=5","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1383\/wohm.1.1.38.55418","volume":"1","author":"Jebb S.","year":"2004","unstructured":"Jebb S.; Obesity: causes and consequences. Women\u2019s Health Med 2004,1(1),38-41","journal-title":"Women\u2019s Health Med"},{"key":"ref=6","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1136\/hrt.2010.211201","volume":"97","author":"Logue J.","year":"2011","unstructured":"Logue J.; Murray H.M.; Welsh P.; Shepherd J.; Packard C.; Macfarlane P.; Cobbe S.; Ford I.; Sattar N.; Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. Heart 2011,97(7),564-568","journal-title":"Heart"},{"key":"ref=7","doi-asserted-by":"publisher","first-page":"335","DOI":"10.2147\/ijgm.s11926","volume":"3","author":"Zammit C.","year":"2010","unstructured":"Zammit C.; Liddicoat H.; Moonsie I.; Makker H.; Obesity and respiratory diseases. Int J Gen Med 2010,3,335-343","journal-title":"Int J Gen Med"},{"key":"ref=8","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1634\/theoncologist.2009-0285","volume":"15","author":"Wolin K.Y.","year":"2010","unstructured":"Wolin K.Y.; Carson K.; Colditz G.A.; Obesity and cancer. Oncologist 2010,15(6),556-565","journal-title":"Oncologist"},{"key":"ref=9","doi-asserted-by":"publisher","first-page":"587","DOI":"10.2147\/DMSO.S67400","volume":"7","author":"Al-Goblan A.S.","year":"2014","unstructured":"Al-Goblan A.S.; Al-Alfi M.A.; Khan M.Z.; Mechanism linking diabetes mellitus and obesity. Diabetes Metab Syndr Obes 2014,7,587-591","journal-title":"Diabetes Metab Syndr Obes"},{"key":"ref=10","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.ogc.2012.09.002","volume":"39","author":"Jungheim E.S.","year":"2012","unstructured":"Jungheim E.S.; Travieso J.L.; Carson K.R.; Moley K.H.; Obesity and reproductive function. Obstet Gynecol Clin North Am 2012,39(4),479-493","journal-title":"Obstet Gynecol Clin North Am"},{"key":"ref=11","year":"2017","unstructured":"W.H.O. Portugal - WHO Country ProfileAvailable at:  ext-link-type=\"uri\"\n                xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0007\/355993\/Health-Profile-Portugal-Eng.pdf\">https:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0007\/355993\/Health-Profile-Portugal-Eng.pdf(Accessed: 5 Jauary, 2018)2017"},{"key":"ref=12","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1098\/rspb.2010.1890","volume":"278","author":"Klimentidis Y.C.","year":"2011","unstructured":"Klimentidis Y.C.; Beasley T.M.; Lin H.Y.; Murati G.; Glass G.E.; Guyton M.; Newton W.; Jorgensen M.; Heymsfield S.B.; Kemnitz J.; Fairbanks L.; Allison D.B.; Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics. Proc Biol Sci 2011,278(1712),1626-1632","journal-title":"Proc Biol Sci"},{"key":"ref=13","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1038\/ncpendmet0220","volume":"2","author":"Lustig R.H.","year":"2006","unstructured":"Lustig R.H.; Childhood obesity: behavioral aberration or biochemical drive? Reinterpreting the first law of thermodynamics. Nat Clin Pract Endocrinol Metab 2006,2(8),447-458","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"ref=14","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1089\/107555302317371479","volume":"8","author":"Baillie-Hamilton P.F.","year":"2002","unstructured":"Baillie-Hamilton P.F.; Chemical toxins: a hypothesis to explain the global obesity epidemic. J Altern Complement Med 2002,8(2),185-192","journal-title":"J Altern Complement Med"},{"key":"ref=15","doi-asserted-by":"publisher","first-page":"S50","DOI":"10.1210\/en.2005-1129","volume":"147","author":"Gr\u00fcn F.","year":"2006","unstructured":"Gr\u00fcn F.; Blumberg B.; Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology 2006,147(6)(Suppl.),S50-S55","journal-title":"Endocrinology"},{"key":"ref=16","first-page":"66","volume":"65","author":"Ritter L.","year":"1995","unstructured":"Ritter L.; Solomon K.; Forget J.; Stemeroff M.; O\u2019leary C.; A review of selected persistent organic pollutants. International Programme on Chemical Safety (IPCS);\nPCS\/9539 Geneva: World Health Organization 1995,65,66","journal-title":"International Programme on Chemical Safety (IPCS);\nPCS\/9539 Geneva: World Health Organization"},{"key":"ref=17","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1186\/1471-2458-12-298","volume":"12","author":"Ruzzin J.","year":"2012","unstructured":"Ruzzin J.; Public health concern behind the exposure to persistent organic pollutants and the risk of metabolic diseases. BMC Public Health 2012,12,298","journal-title":"BMC Public Health"},{"key":"ref=18","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1021\/es00014a005","volume":"25","author":"Dearth M.A.","year":"1991","unstructured":"Dearth M.A.; Hites R.A.; Complete analysis of technical chlordane using negative ionization mass spectrometry. Environ Sci Technol 1991,25(2),245-254","journal-title":"Environ Sci Technol"},{"key":"ref=19","author":"Eisler R.","year":"2007","unstructured":"Eisler R.;  Chlordane Eisler\u2019s Encyclopedia of Environmentally Hazardous Priority Chemicals 2007","journal-title":"Chlordane Eisler\u2019s Encyclopedia of Environmentally Hazardous Priority Chemicals"},{"key":"ref=20","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1093\/toxsci\/58.2.386","volume":"58","author":"Bondy G.S.","year":"2000","unstructured":"Bondy G.S.; Newsome W.H.; Armstrong C.L.; Suzuki C.A.M.; Doucet J.; Fernie S.; Hierlihy S.L.; Feeley M.M.; Barker M.G.; Trans-nonachlor and cis-nonachlor toxicity in Sprague-dawley rats: comparison with technical chlordane. Toxicol Sci 2000,58(2),386-398","journal-title":"Toxicol Sci"},{"key":"ref=21","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/s0278-6915(02)00229-6","volume":"41","author":"Bondy G.","year":"2003","unstructured":"Bondy G.; Armstrong C.; Coady L.; Doucet J.; Robertson P.; Feeley M.; Barker M.; Toxicity of the chlordane metabolite oxychlordane in female rats: clinical and histopathological changes. Food Chem Toxicol 2003,41(2),291-301","journal-title":"Food Chem Toxicol"},{"key":"ref=22","author":"Eisler R.","year":"1990","unstructured":"Eisler R.;  Chlordane Hazards to Fish, Wildlife, and Invertebrates: A Synoptic Review Contaminant Hazard Reviews Report 21; Biological Report 85(121) 1990","journal-title":"Chlordane Hazards to Fish, Wildlife, and Invertebrates: A Synoptic Review Contaminant Hazard Reviews Report 21; Biological Report 85(121)"},{"key":"ref=23","doi-asserted-by":"publisher","first-page":"a62","DOI":"10.1289\/ehp.120-a62","volume":"120","author":"Holtcamp W.","year":"2012","unstructured":"Holtcamp W.; Obesogens: an environmental link to obesity. Environ Health Perspect 2012,120(2),a62-a68","journal-title":"Environ Health Perspect"},{"key":"ref=24","year":"2017","unstructured":"Endocrine Disruptors NIEHSAvailable at:  ext-link-type=\"uri\"\n                xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.niehs.nih.gov\/health\/topics\/agents\/endocrine\/index.cfm2017\">https:\/\/www.niehs.nih.gov\/health\/topics\/agents\/endocrine\/index.cfm2017(Accessed: 15 Jauary, 2018)2017"},{"key":"ref=25","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1210\/me.2016-1096","volume":"30","author":"Schug T.T.","year":"2016","unstructured":"Schug T.T.; Johnson A.F.; Birnbaum L.S.; Colborn T.; Guillette L.J.; Crews D.P.; Collins T.; Soto A.M.; Vom Saal F.S.; McLachlan J.A.; Sonnenschein C.; Heindel J.J.; Minireview: endocrine disruptors: past lessons and future directions. Mol Endocrinol 2016,30(8),833-847","journal-title":"Mol Endocrinol"},{"key":"ref=26","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.etap.2015.06.009","volume":"40","author":"Kabir E.R.","year":"2015","unstructured":"Kabir E.R.; Rahman M.S.; Rahman I.; A review on endocrine disruptors and their possible impacts on human health. Environ Toxicol Pharmacol 2015,40(1),241-258","journal-title":"Environ Toxicol Pharmacol"},{"key":"ref=27","author":"Colborn T.","year":"1992","unstructured":"Colborn T.; Clement C.;  Chemically-Induced Alterations\nin Sexual and Functional Development: The Wildlife\/Human Connection 1992","journal-title":"Chemically-Induced Alterations\nin Sexual and Functional Development: The Wildlife\/Human Connection"},{"key":"ref=28","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1289\/ehp.94102680","volume":"102","author":"Guillette L.J.","year":"1994","unstructured":"Guillette L.J.; Gross T.S.; Masson G.R.; Matter J.M.; Percival H.F.; Woodward A.R.; Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ Health Perspect 1994,102(8),680-688","journal-title":"Environ Health Perspect"},{"key":"ref=29","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1006\/gcen.1996.0005","volume":"101","author":"Guillette L.J.","year":"1996","unstructured":"Guillette L.J.; Jr.; Pickford, D.B.; Crain, D.A.; Rooney, A.A.; Percival, H.F. Reduction in penis size and plasma testosterone concentrations in juvenile alligators living in a contaminated environment. Gen Comp Endocrinol 1996,101(1),32-42","journal-title":"Gen Comp Endocrinol"},{"key":"ref=30","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1289\/ehp.95103s7165","volume":"103","author":"Fry D.M.","year":"1995","unstructured":"Fry D.M.; Reproductive effects in birds exposed to pesticides and industrial chemicals. Environ Health Perspect 1995,103(Suppl. 7),165-171","journal-title":"Environ Health Perspect"},{"key":"ref=31","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/0002-9378(48)90440-2","volume":"56","author":"Smith O.W.","year":"1948","unstructured":"Smith O.W.; Diethylstilbestrol in the prevention and treatment of complications of pregnancy. Am J Obstet Gynecol 1948,56(5),821-834","journal-title":"Am J Obstet Gynecol"},{"key":"ref=32","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/s0029-7844(00)00959-5","volume":"96","author":"Kaufman R.H.","year":"2000","unstructured":"Kaufman R.H.; Adam E.; Hatch E.E.; Noller K.; Herbst A.L.; Palmer J.R.; Hoover R.N.; Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring. Obstet Gynecol 2000,96(4),483-489","journal-title":"Obstet Gynecol"},{"key":"ref=33","author":"Bergman \u00c5.","year":"2013","unstructured":"Bergman \u00c5.; Heindel J.J.; Jobling S.; Kidd K.; Zoeller T.R.;  State of the Science of Endocrine Disrupting Chemicals 2012 2013","journal-title":"State of the Science of Endocrine Disrupting Chemicals 2012"},{"key":"ref=34","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.yfrne.2010.03.003","volume":"31","author":"Patisaul H.B.","year":"2010","unstructured":"Patisaul H.B.; Jefferson W.; The pros and cons of phytoestrogens. Front Neuroendocrinol 2010,31(4),400-419","journal-title":"Front Neuroendocrinol"},{"key":"ref=35","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.amjmed.2009.04.018","volume":"122","author":"Tempfer C.B.","year":"2009","unstructured":"Tempfer C.B.; Froese G.; Heinze G.; Bentz E-K.; Hefler L.A.; Huber J.C.; Side effects of phytoestrogens: a meta-analysis of randomized trials. Am J Med 2009,122(10),939-46.e9","journal-title":"Am J Med"},{"key":"ref=36","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.2174\/0929867321666131129124640","volume":"21","author":"Albini A.","year":"2014","unstructured":"Albini A.; Rosano C.; Angelini G.; Amaro A.; Esposito A.I.; Maramotti S.; Noonan D.M.; Pfeffer U.; Exogenous hormonal regulation in breast cancer cells by phytoestrogens and endocrine disruptors. Curr Med Chem 2014,21(9),1129-1145","journal-title":"Curr Med Chem"},{"key":"ref=37","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s13679-017-0240-4","volume":"6","author":"Darbre P.D.","year":"2017","unstructured":"Darbre P.D.; Endocrine disruptors and obesity. Curr Obes Rep 2017,6(1),18-27","journal-title":"Curr Obes Rep"},{"key":"ref=38","first-page":"1","author":"Gore A.C.","year":"2014","unstructured":"Gore A.C.; Crews D.; Doan L.L.; La Merrill M.; Patisaul H.; Zota A.;  Introduction to endocrine disrupting chemicals (EDCs) 2014,1-69","journal-title":"Introduction to endocrine disrupting chemicals (EDCs)"},{"key":"ref=39","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1289\/ehp.11748","volume":"117","author":"Eskenazi B.","year":"2009","unstructured":"Eskenazi B.; Chevrier J.; Rosas L.G.; Anderson H.A.; Bornman M.S.; Bouwman H.; Chen A.; Cohn B.A.; de Jager C.; Henshel D.S.; Leipzig F.; Leipzig J.S.; Lorenz E.C.; Snedeker S.M.; Stapleton D.; The pine river statement: human health consequences of DDT use. Environ Health Perspect 2009,117(9),1359-1367","journal-title":"Environ Health Perspect"},{"key":"ref=40","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.jhazmat.2017.06.036","volume":"340","author":"Benjamin S.","year":"2017","unstructured":"Benjamin S.; Masai E.; Kamimura N.; Takahashi K.; Anderson R.C.; Faisal P.A.; Phthalates impact human health: epidemiological evidences and plausible mechanism of action. J Hazard Mater 2017,340,360-383","journal-title":"J Hazard Mater"},{"key":"ref=41","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1210\/er.2009-0002","volume":"30","author":"Diamanti-Kandarakis E.","year":"2009","unstructured":"Diamanti-Kandarakis E.; Bourguignon J-P.; Giudice L.C.; Hauser R.; Prins G.S.; Soto A.M.; Zoeller R.T.; Gore A.C.; Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev 2009,30(4),293-342","journal-title":"Endocr Rev"},{"key":"ref=42","doi-asserted-by":"publisher","first-page":"R15","DOI":"10.1530\/EC-13-0036","volume":"2","author":"Marques-Pinto A.","year":"2013","unstructured":"Marques-Pinto A.; Carvalho D.; Human infertility: are endocrine disruptors to blame? Endocr Connect 2013,2(3),R15-R29","journal-title":"Endocr Connect"},{"key":"ref=43","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/S1472-6483(10)60530-5","volume":"15","author":"Giwercman A.","year":"2007","unstructured":"Giwercman A.; Rylander L.; Lundberg Giwercman Y.; Influence of endocrine disruptors on human male fertility. Reprod Biomed Online 2007,15(6),633-642","journal-title":"Reprod Biomed Online"},{"key":"ref=44","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1136\/bmj.312.7029.471","volume":"312","author":"Bujan L.","year":"1996","unstructured":"Bujan L.; Mansat A.; Pontonnier F.; Mieusset R.; Time series analysis of sperm concentration in fertile men in Toulouse, France between 1977 and 1992. BMJ 1996,312(7029),471-472","journal-title":"BMJ"},{"key":"ref=45","first-page":"209","volume":"67","author":"Dobrzy\u0144ska M.M.","year":"2016","unstructured":"Dobrzy\u0144ska M.M.; Phthalates - widespread occurrence and the effect on male gametes. Part 2. The effects of phthalates on male gametes and on the offspring. Rocz Panstw Zakl Hig 2016,67(3),209-221","journal-title":"Rocz Panstw Zakl Hig"},{"key":"ref=46","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.beem.2005.09.009","volume":"20","author":"McLachlan J.A.","year":"2006","unstructured":"McLachlan J.A.; Simpson E.; Martin M.; Endocrine disrupters and female reproductive health. Best Pract Res Clin Endocrinol Metab 2006,20(1),63-75","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref=47","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.reprotox.2013.09.008","volume":"42","author":"Souter I.","year":"2013","unstructured":"Souter I.; Smith K.W.; Dimitriadis I.; Ehrlich S.; Williams P.L.; Calafat A.M.; Hauser R.; The association of bisphenol-A urinary concentrations with antral follicle counts and other measures of ovarian reserve in women undergoing infertility treatments. Reprod Toxicol 2013,42,224-231","journal-title":"Reprod Toxicol"},{"key":"ref=48","doi-asserted-by":"publisher","first-page":"2735","DOI":"10.1093\/humrep\/det312","volume":"28","author":"Machtinger R.","year":"2013","unstructured":"Machtinger R.; Combelles C.M.; Missmer S.A.; Correia K.F.; Williams P.; Hauser R.; Racowsky C.; Bisphenol-A and human oocyte maturation in vitro. Hum Reprod 2013,28(10),2735-2745","journal-title":"Hum Reprod"},{"key":"ref=49","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122583","volume":"18","author":"Calsolaro V.","year":"2017","unstructured":"Calsolaro V.; Pasqualetti G.; Niccolai F.; Caraccio N.; Monzani F.; Thyroid disrupting chemicals. Int J Mol Sci 2017,18(12)","journal-title":"Int J Mol Sci"},{"key":"ref=50","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.1210\/jc.2002-020209","volume":"87","author":"Moriyama K.","year":"2002","unstructured":"Moriyama K.; Tagami T.; Akamizu T.; Usui T.; Saijo M.; Kanamoto N.; Hataya Y.; Shimatsu A.; Kuzuya H.; Nakao K.; Thyroid hormone action is disrupted by bisphenol A as an antagonist. J Clin Endocrinol Metab 2002,87(11),5185-5190","journal-title":"J Clin Endocrinol Metab"},{"key":"ref=51","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1210\/endo.141.1.7273","volume":"141","author":"Zoeller R.T.","year":"2000","unstructured":"Zoeller R.T.; Dowling A.L.; Vas A.A.; Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3\/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain. Endocrinology 2000,141(1),181-189","journal-title":"Endocrinology"},{"key":"ref=52","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1111\/j.0272-4332.2004.00557.x","volume":"24","author":"Crofton K.M.","year":"2004","unstructured":"Crofton K.M.; Developmental disruption of thyroid hormone: correlations with hearing dysfunction in rats. Risk Anal 2004,24(6),1665-1671","journal-title":"Risk Anal"},{"key":"ref=53","doi-asserted-by":"publisher","first-page":"535","DOI":"10.2131\/jts.35.535","volume":"35","author":"Lee E.","year":"2010","unstructured":"Lee E.; Kim T.H.; Choi J.S.; Nabanata P.; Kim N.Y.; Ahn M.Y.; Jung K.K.; Kang I.H.; Kim T.S.; Kwack S.J.; Park K.L.; Kim S.H.; Kang T.S.; Lee J.; Lee B.M.; Kim H.S.; Evaluation of liver and thyroid toxicity in Sprague-dawley rats after exposure to polybrominated diphenyl ether BDE-209. J Toxicol Sci 2010,35(4),535-545","journal-title":"J Toxicol Sci"},{"key":"ref=54","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.envres.2008.08.008","volume":"108","author":"Talsness C.E.","year":"2008","unstructured":"Talsness C.E.; Overview of toxicological aspects of polybrominated diphenyl ethers: a flame-retardant additive in several consumer products. Environ Res 2008,108(2),158-167","journal-title":"Environ Res"},{"key":"ref=55","doi-asserted-by":"publisher","first-page":"4097","DOI":"10.1210\/en.2012-1422","volume":"153","author":"Zoeller R.T.","year":"2012","unstructured":"Zoeller R.T.; Brown T.R.; Doan L.L.; Gore A.C.; Skakkebaek N.E.; Soto A.M.; Woodruff T.J.; Vom Saal F.S.; Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. Endocrinology 2012,153(9),4097-4110","journal-title":"Endocrinology"},{"key":"ref=56","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1373\/clinchem.2004.032482","volume":"50","author":"Meier U.","year":"2004","unstructured":"Meier U.; Gressner A.M.; Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem 2004,50(9),1511-1525","journal-title":"Clin Chem"},{"key":"ref=57","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s11154-013-9261-9","volume":"14","author":"Rui L.","year":"2013","unstructured":"Rui L.; Brain regulation of energy balance and body weight. Rev Endocr Metab Disord 2013,14(4),387-407","journal-title":"Rev Endocr Metab Disord"},{"key":"ref=58","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.reprotox.2016.10.001","volume":"68","author":"Heindel J.J.","year":"2017","unstructured":"Heindel J.J.; Blumberg B.; Cave M.; Machtinger R.; Mantovani A.; Mendez M.A.; Nadal A.; Palanza P.; Panzica G.; Sargis R.; Vandenberg L.N.; Vom Saal F.; Metabolism disrupting chemicals and metabolic disorders. Reprod Toxicol 2017,68,3-33","journal-title":"Reprod Toxicol"},{"key":"ref=59","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1111\/bcpt.13214","volume":"125","author":"Lee M.K.","year":"2019","unstructured":"Lee M.K.; Blumberg B.; Transgenerational effects of obesogens. Basic Clin Pharmacol Toxicol 2019,125(Suppl. 3),44-57","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"ref=60","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1146\/annurev-pharmtox-010818-021304","volume":"59","author":"Heindel J.J.","year":"2019","unstructured":"Heindel J.J.; Blumberg B.; Environmental obesogens: mechanisms and controversies. Annu Rev Pharmacol Toxicol 2019,59,89-106","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"ref=61","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.1210\/jc.2004-0395","volume":"89","author":"Kershaw E.E.","year":"2004","unstructured":"Kershaw E.E.; Flier J.S.; Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004,89(6),2548-2556","journal-title":"J Clin Endocrinol Metab"},{"key":"ref=62","doi-asserted-by":"crossref","first-page":"375","DOI":"10.33549\/physiolres.931022","volume":"56","author":"M\u00fcllerov\u00e1 D.","year":"2007","unstructured":"M\u00fcllerov\u00e1 D.; Kopeck\u00fd J.; White adipose tissue: storage and effector site for environmental pollutants. Physiol Res 2007,56(4),375-381","journal-title":"Physiol Res"},{"key":"ref=63","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1038\/sj.ijo.0801380","volume":"24","author":"Chevrier J.","year":"2000","unstructured":"Chevrier J.; Dewailly E.; Ayotte P.; Mauri\u00e8ge P.; Despr\u00e9s J.P.; Tremblay A.; Body weight loss increases plasma and adipose tissue concentrations of potentially toxic pollutants in obese individuals. Int J Obes Relat Metab Disord 2000,24(10),1272-1278","journal-title":"Int J Obes Relat Metab Disord"},{"key":"ref=64","doi-asserted-by":"publisher","first-page":"a61","DOI":"10.1289\/ehp.121-a61","volume":"121","author":"Barrett J.R.","year":"2013","unstructured":"Barrett J.R.; POPs vs. fat: persistent organic pollutant toxicity targets and is modulated by adipose tissue. Environ Health Perspect 2013,121(2),a61","journal-title":"Environ Health Perspect"},{"key":"ref=65","first-page":"4356","volume":"57","author":"Li S.","year":"1997","unstructured":"Li S.; Washburn K.A.; Moore R.; Uno T.; Teng C.; Newbold R.R.; McLachlan J.A.; Negishi M.; Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus. Cancer Res 1997,57(19),4356-4359","journal-title":"Cancer Res"},{"key":"ref=66","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1095\/biolreprod.103.025387","volume":"70","author":"Wu Q.","year":"2004","unstructured":"Wu Q.; Ohsako S.; Ishimura R.; Suzuki J.S.; Tohyama C.; Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2. Biol Reprod 2004,70(6),1790-1797","journal-title":"Biol Reprod"},{"key":"ref=67","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1002\/bdra.20685","volume":"88","author":"Bernal A.J.","year":"2010","unstructured":"Bernal A.J.; Jirtle R.L.; Epigenomic disruption: the effects of early developmental exposures. Birth Defects Res A Clin Mol Teratol 2010,88(10),938-944","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"ref=68","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1289\/ehp.01109675","volume":"109","author":"Rubin B.S.","year":"2001","unstructured":"Rubin B.S.; Murray M.K.; Damassa D.A.; King J.C.; Soto A.M.; Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels. Environ Health Perspect 2001,109(7),675-680","journal-title":"Environ Health Perspect"},{"key":"ref=69","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1002\/bdra.20147","volume":"73","author":"Newbold R.R.","year":"2005","unstructured":"Newbold R.R.; Padilla-Banks E.; Snyder R.J.; Jefferson W.N.; Developmental exposure to estrogenic compounds and obesity. Birth Defects Res A Clin Mol Teratol 2005,73(7),478-480","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"ref=70","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S0006-291X(03)01359-7","volume":"308","author":"Atanasov A.G.","year":"2003","unstructured":"Atanasov A.G.; Tam S.; R\u00f6cken J.M.; Baker M.E.; Odermatt A.; Inhibition of 11 beta-hydroxysteroid dehydrogenase type 2 by dithiocarbamates. Biochem Biophys Res Commun 2003,308(2),257-262","journal-title":"Biochem Biophys Res Commun"},{"key":"ref=71","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1289\/ehp.8209","volume":"113","author":"Atanasov A.G.","year":"2005","unstructured":"Atanasov A.G.; Nashev L.G.; Tam S.; Baker M.E.; Odermatt A.; Organotins disrupt the 11beta-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids. Environ Health Perspect 2005,113(11),1600-1606","journal-title":"Environ Health Perspect"},{"key":"ref=72","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1210\/me.2009-0261","volume":"24","author":"Kirchner S.","year":"2010","unstructured":"Kirchner S.; Kieu T.; Chow C.; Casey S.; Blumberg B.; Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol 2010,24(3),526-539","journal-title":"Mol Endocrinol"},{"key":"ref=73","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1111\/j.1365-2605.2012.01247.x","volume":"35","author":"Janesick A.","year":"2012","unstructured":"Janesick A.; Blumberg B.; Obesogens, stem cells and the developmental programming of obesity. Int J Androl 2012,35(3),437-448","journal-title":"Int J Androl"},{"key":"ref=74","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1006\/bbrc.2001.5952","volume":"289","author":"Saitoh M.","year":"2001","unstructured":"Saitoh M.; Yanase T.; Morinaga H.; Tanabe M.; Mu Y.M.; Nishi Y.; Nomura M.; Okabe T.; Goto K.; Takayanagi R.; Nawata H.; Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN. Biochem Biophys Res Commun 2001,289(1),198-204","journal-title":"Biochem Biophys Res Commun"},{"key":"ref=75","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.mce.2009.02.018","volume":"304","author":"Gr\u00fcn F.","year":"2009","unstructured":"Gr\u00fcn F.; Blumberg B.; Endocrine disrupters as obesogens. Mol Cell Endocrinol 2009,304(1-2),19-29","journal-title":"Mol Cell Endocrinol"},{"key":"ref=76","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/S1097-2765(00)80211-7","volume":"4","author":"Rosen E.D.","year":"1999","unstructured":"Rosen E.D.; Sarraf P.; Troy A.E.; Bradwin G.; Moore K.; Milstone D.S.; Spiegelman B.M.; Mortensen R.M.; PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 1999,4(4),611-617","journal-title":"Mol Cell"},{"key":"ref=77","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1038\/nm.2332","volume":"17","author":"Lu M.","year":"2011","unstructured":"Lu M.; Sarruf D.A.; Talukdar S.; Sharma S.; Li P.; Bandyopadhyay G.; Nalbandian S.; Fan W.; Gayen J.R.; Mahata S.K.; Webster N.J.; Schwartz M.W.; Olefsky J.M.; Brain PPAR-\u03b3 promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med 2011,17(5),618-622","journal-title":"Nat Med"},{"key":"ref=78","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/nm.2349","volume":"17","author":"Ryan K.K.","year":"2011","unstructured":"Ryan K.K.; Li B.; Grayson B.E.; Matter E.K.; Woods S.C.; Seeley R.J.; A role for central nervous system PPAR-\u03b3 in the regulation of energy balance. Nat Med 2011,17(5),623-626","journal-title":"Nat Med"},{"key":"ref=79","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1172\/JCI88894","volume":"127","author":"Dubois V.","year":"2017","unstructured":"Dubois V.; Eeckhoute J.; Lefebvre P.; Staels B.; Distinct but complementary contributions of PPAR isotypes to energy homeostasis. J Clin Invest 2017,127(4),1202-1214","journal-title":"J Clin Invest"},{"key":"ref=80","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.1007\/s00204-017-2071-1","volume":"91","author":"Muscogiuri G.","year":"2017","unstructured":"Muscogiuri G.; Barrea L.; Laudisio D.; Savastano S.; Colao A.; Obesogenic endocrine disruptors and obesity: myths and truths. Arch Toxicol 2017,91(11),3469-3475","journal-title":"Arch Toxicol"},{"key":"ref=81","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s12940-017-0338-x","volume":"17","author":"Lauritzen H.B.","year":"2018","unstructured":"Lauritzen H.B.; Larose T.L.; \u00d8ien T.; Sandanger T.M.; Odland J.\u00d8.; van de Bor M.; Jacobsen G.W.; Prenatal exposure to persistent organic pollutants and child overweight\/obesity at 5-year follow-up: a prospective cohort study. Environ Health 2018,17(1),9","journal-title":"Environ Health"},{"key":"ref=82","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1017\/S2040174418000995","volume":"9","author":"Kadawathagedara M.","year":"2018","unstructured":"Kadawathagedara M.; de Lauzon-Guillain B.; Botton J.; Environmental contaminants and child\u2019s growth. J Dev Orig Health Dis 2018,9(6),632-641","journal-title":"J Dev Orig Health Dis"},{"key":"ref=83","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.ajog.2016.01.182","volume":"214","author":"Janesick A.S.","year":"2016","unstructured":"Janesick A.S.; Blumberg B.; Obesogens: an emerging threat to public health. Am J Obstet Gynecol 2016,214(5),559-565","journal-title":"Am J Obstet Gynecol"},{"key":"ref=84","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1289\/ehp.1205701","volume":"121","author":"Chamorro-Garc\u00eda R.","year":"2013","unstructured":"Chamorro-Garc\u00eda R.; Sahu M.; Abbey R.J.; Laude J.; Pham N.; Blumberg B.; Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice. Environ Health Perspect 2013,121(3),359-366","journal-title":"Environ Health Perspect"},{"key":"ref=85","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/B978-0-12-801139-3.00015-6","author":"Darbre P.D.","year":"2015","unstructured":"Darbre P.D.;  Endocrine disruption and disorders of energy metabolism 2015,273-285","journal-title":"Endocrine disruption and disorders of energy metabolism"},{"key":"ref=86","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0269-7491(99)00098-6","volume":"100","author":"Jones K.C.","year":"1999","unstructured":"Jones K.C.; de Voogt P.; Persistent organic pollutants (POPs): state of the science. Environ Pollut 1999,100(1-3),209-221","journal-title":"Environ Pollut"},{"key":"ref=87","author":"Beyer W.N.","year":"2011","unstructured":"Beyer W.N.; Meador J.P.;  Environmental Contaminants in Biota: Interpreting Tissue Concentrations 2011","journal-title":"Environmental Contaminants in Biota: Interpreting Tissue Concentrations"},{"key":"ref=88","year":"2018","unstructured":"Toxicological profile for chlordane Department of Health and Human Services ATSDR2018","journal-title":"Toxicological profile for chlordane Department of Health and Human Services"},{"key":"ref=89","author":"Ingle L.","year":"1965","unstructured":"Ingle L.;  A monograph on chlordane Toxicological and\nPharmacological Properties, A Monograph on Chlordane, 1965","journal-title":"A monograph on chlordane Toxicological and\nPharmacological Properties, A Monograph on Chlordane,"},{"key":"ref=90","author":"Seager J.","year":"2014","unstructured":"Seager J.;  Carson\u2019s Silent Spring: A Reader\u2019s Guide 2014","journal-title":"Carson\u2019s Silent Spring: A Reader\u2019s Guide"},{"key":"ref=91","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1080\/00039896.1969.10666814","volume":"19","author":"Aldrich F.D.","year":"1969","unstructured":"Aldrich F.D.; Holmes J.H.; Acute chlordane intoxication in a child. Case report with toxicological data. Arch Environ Health 1969,19(1),129-132","journal-title":"Arch Environ Health"},{"key":"ref=92","first-page":"115","volume":"53","year":"1991","unstructured":"Chlordane and heptachlor. IARC Monogr Eval Carcinog Risks Hum 1991,53,115-175","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"ref=93","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1021\/jf00103a023","volume":"29","author":"Beeman R.W.","year":"1981","unstructured":"Beeman R.W.; Matsumura F.; Metabolism of cis-and trans-chlordane by a soil microorganism. J Agric Food Chem 1981,29(1),84-89","journal-title":"J Agric Food Chem"},{"key":"ref=94","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.chemosphere.2017.01.044","volume":"173","author":"Fuentes M.S.","year":"2017","unstructured":"Fuentes M.S.; Raimondo E.E.; Amoroso M.J.; Benimeli C.S.; Removal of a mixture of pesticides by a Streptomyces consortium: influence of different soil systems. Chemosphere 2017,173,359-367","journal-title":"Chemosphere"},{"key":"ref=95","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/B978-0-12-800020-5.00022-3","author":"Reinke E.N.","year":"2015","unstructured":"Reinke E.N.; Deck A.T.;  Wildlife Toxicity Assessments for Chemicals of Military Concern 2015,385-411","journal-title":"Wildlife Toxicity Assessments for Chemicals of Military Concern"},{"key":"ref=96","year":"1987","unstructured":"EPA. Chlordane, heptachlor, aldrin, and dieldrin technical\nsupport document (Draft).  In: OoPPaOoPaT 1987","journal-title":"In: OoPPaOoPaT"},{"key":"ref=97","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1007\/BF01689578","volume":"39","author":"Louis J.B.","year":"1987","unstructured":"Louis J.B.; Kisselbach K.C.; Jr. Indoor air levels of chlordane and heptachlor following termiticide applications. Bull Environ Contam Toxicol 1987,39(6),911-918","journal-title":"Bull Environ Contam Toxicol"},{"key":"ref=98","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/BF00212082","volume":"22","author":"Kamble S.T.","year":"1992","unstructured":"Kamble S.T.; Ogg C.L.; Gold R.E.; Vance A.D.; Exposure of applicators and residents to chlordane and heptachlor when used for subterranean termite control. Arch Environ Contam Toxicol 1992,22(3),253-259","journal-title":"Arch Environ Contam Toxicol"},{"key":"ref=99","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.marpolbul.2013.05.017","volume":"73","author":"Byun G.H.","year":"2013","unstructured":"Byun G.H.; Moon H.B.; Choi J.H.; Hwang J.; Kang C.K.; Biomagnification of persistent chlorinated and brominated contaminants in food web components of the Yellow Sea. Mar Pollut Bull 2013,73(1),210-219","journal-title":"Mar Pollut Bull"},{"key":"ref=100","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/BF01055900","volume":"20","author":"Ford W.M.","year":"1991","unstructured":"Ford W.M.; Hill E.P.; Organochlorine pesticides in soil sediments and aquatic animals in the Upper Steele Bayou watershed of Mississippi. Arch Environ Contam Toxicol 1991,20(2),161-167","journal-title":"Arch Environ Contam Toxicol"},{"key":"ref=101","first-page":"229","volume":"51","author":"Falandysz J.","year":"2000","unstructured":"Falandysz J.; Quantity of chlordane intake with seafood in Poland. Rocz Panstw Zakl Hig 2000,51(3),229-239","journal-title":"Rocz Panstw Zakl Hig"},{"key":"ref=102","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/BF02332042","volume":"7","author":"Tashiro S.","year":"1978","unstructured":"Tashiro S.; Matsumura F.; Metabolism of trans-nonachlor and related chlordane components in rat and man. Arch Environ Contam Toxicol 1978,7(1),113-127","journal-title":"Arch Environ Contam Toxicol"},{"key":"ref=103","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/0378-4274(89)90065-9","volume":"47","author":"Hirasawa F.","year":"1989","unstructured":"Hirasawa F.; Takizawa Y.; Accumulation and declination of chlordane congeners in mice. Toxicol Lett 1989,47(2),109-117","journal-title":"Toxicol Lett"},{"key":"ref=104","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-1-4612-4804-0_1","volume":"100","author":"Nomeir A.A.","year":"1987","unstructured":"Nomeir A.A.; Hajjar N.P.; Metabolism of chlordane in mammals. Rev Environ Contam Toxicol 1987,100,1-22","journal-title":"Rev Environ Contam Toxicol"},{"key":"ref=105","doi-asserted-by":"publisher","DOI":"10.17226\/4795 25121193","year":"1995","unstructured":"Pope, AM; Rall, DP, Ed; Washington (DC): National Academies Press (US); Institute of Medicine (US) Committee on Curriculum Development in Environmental Medicine1995","journal-title":"Pope, AM; Rall, DP, Ed; Washington (DC): National Academies Press (US);"},{"key":"ref=106","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1016\/0045-6535(89)90006-4","volume":"19","author":"Kawano M.","year":"1989","unstructured":"Kawano M.; Nishiyama N.; Tatsukawa R.; Shimada T.; In vitro degradation of trans-chlordane and oxychlordane by rat liver microsomes. Chemosphere 1989,19(12),1829-1833","journal-title":"Chemosphere"},{"key":"ref=107","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/0048-3575(78)90069-X","volume":"9","author":"Brimfield A.A.","year":"1978","unstructured":"Brimfield A.A.; Street J.C.; Futrell J.; Chatfield D.A.; Identification of products arising from the metabolism of cis- and trans-chlordane in rat liver microsomes in vitro: outline of a possible metabolic pathway. Pestic Biochem Physiol 1978,9(1),84-95","journal-title":"Pestic Biochem Physiol"},{"key":"ref=108","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/0041-008X(88)90033-6","volume":"93","author":"Suzaki E.","year":"1988","unstructured":"Suzaki E.; Inoue B.; Okimasu E.; Ogata M.; Utsumi K.; Stimulative effect of chlordane on the various functions of the guinea pig leukocytes. Toxicol Appl Pharmacol 1988,93(1),137-145","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref=109","doi-asserted-by":"publisher","first-page":"111","DOI":"10.2131\/jts.11.111","volume":"11","author":"Ohno Y.","year":"1986","unstructured":"Ohno Y.; Kawanishi T.; Takahashi A.; Nakaura S.; Kawashima K.; Tanaka S.; Takanaka A.; Omori Y.; Sekita H.; Uchiyama M.; Comparisons of the toxicokinetic parameters in rats determined for low and high dose of gamma-chlordane. J Toxicol Sci 1986,11(2),111-123","journal-title":"J Toxicol Sci"},{"key":"ref=110","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1001\/jama.1955.02960150037011a","volume":"158","author":"Derbes V.J.","year":"1955","unstructured":"Derbes V.J.; Dent J.H.; Forrest W.W.; Johnson M.F.; Fatal chlordane poisoning. J Am Med Assoc 1955,158(15),1367-1369","journal-title":"J Am Med Assoc"},{"key":"ref=111","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/BF01812638","volume":"15","author":"Nye D.E.","year":"1976","unstructured":"Nye D.E.; Dorough H.W.; Fate of insecticides administered endotracheally to rats. Bull Environ Contam Toxicol 1976,15(3),291-296","journal-title":"Bull Environ Contam Toxicol"},{"key":"ref=112","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1177\/019262337600400102","volume":"4","author":"Kutz F.","year":"1976","unstructured":"Kutz F.; Yobs A.; Strassman S.; Organochlorine pesticide residues in human adipose tissue. Bulletin of the Society of Pharmacological and Environmental Pathologists 1976,4(1),17-19","journal-title":"Bulletin of the Society of Pharmacological and Environmental Pathologists"},{"key":"ref=113","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/j.1749-6632.1979.tb56593.x","volume":"320","author":"Kutz F.W.","year":"1979","unstructured":"Kutz F.W.; Strassman S.C.; Sperling J.F.; Survey of selected organochlorine pesticides in the general population of the United States: fiscal years 1970-1975. Ann N Y Acad Sci 1979,320,60-68","journal-title":"Ann N Y Acad Sci"},{"key":"ref=114","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1080\/15287398109529995","volume":"7","author":"Barquet A.","year":"1981","unstructured":"Barquet A.; Morgade C.; Pfaffenberger C.D.; Determination of organochlorine pesticides and metabolites in drinking water, human blood serum, and adipose tissue. J Toxicol Environ Health 1981,7(3-4),469-479","journal-title":"J Toxicol Environ Health"},{"key":"ref=115","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/BF01684812","volume":"10","author":"Biros F.J.","year":"1973","unstructured":"Biros F.J.; Enos H.F.; Oxychlordane residues in human adipose tissue. Bull Environ Contam Toxicol 1973,10(5),257-260","journal-title":"Bull Environ Contam Toxicol"},{"key":"ref=116","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/0378-4274(91)90161-X","volume":"56","author":"Ogata M.","year":"1991","unstructured":"Ogata M.; Izushi F.; Effects of chlordane on parameters of liver and muscle toxicity in man and experimental animals. Toxicol Lett 1991,56(3),327-337","journal-title":"Toxicol Lett"},{"key":"ref=117","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1007\/BF02932256","volume":"3","author":"Jitsunari F.","year":"1999","unstructured":"Jitsunari F.; Asakawa F.; Shiraishi H.; Choi J.O.; Suna S.; Yoshihara K.; Fukunaga I.; Takeda N.; Tissue concentrations of chlordanes in mice after long-term exposures to technical grade chlordane at indoor air levels. Environ Health Prev Med 1999,3(4),184-189","journal-title":"Environ Health Prev Med"},{"key":"ref=118","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/BF01055155","volume":"17","author":"Taguchi S.","year":"1988","unstructured":"Taguchi S.; Yakushiji T.; Influence of termite treatment in the home on the chlordane concentration in human milk. Arch Environ Contam Toxicol 1988,17(1),65-71","journal-title":"Arch Environ Contam Toxicol"},{"key":"ref=119","year":"2019","unstructured":"Fourth National Report on Human Exposure to Environmental Chemical. Centers for Disease Control and\nPrevention, Department of Health and Human Services CDC2019","journal-title":"Centers for Disease Control and\nPrevention, Department of Health and Human Services"},{"key":"ref=120","doi-asserted-by":"publisher","first-page":"8989","DOI":"10.1007\/s11356-015-4080-z","volume":"22","author":"F\u00e5ng J.","year":"2015","unstructured":"F\u00e5ng J.; Nyberg E.; Winnberg U.; Bignert A.; Bergman \u00c5.; Spatial and temporal trends of the Stockholm Convention POPs in mothers\u2019 milk - a global review. Environ Sci Pollut Res Int 2015,22(12),8989-9041","journal-title":"Environ Sci Pollut Res Int"},{"key":"ref=121","first-page":"47","volume":"13","author":"Barnett R.W.","year":"1979","unstructured":"Barnett R.W.; D\u2019Ercole A.J.; Cain J.D.; Arthur R.D.; Organochlorine pesticide residues in human milk samples from women living in Northwest and Northeast Mississippi, 1973-75. Pestic Monit J 1979,13(2),47-51","journal-title":"Pestic Monit J"},{"key":"ref=122","first-page":"130","volume":"10","author":"Strassman S.C.","year":"1977","unstructured":"Strassman S.C.; Kutz F.W.; Insecticide residues in human milk from Arkansas and Mississippi, 1973-74. Pestic Monit J 1977,10(4),130-133","journal-title":"Pestic Monit J"},{"key":"ref=123","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.chemosphere.2012.05.098","volume":"89","author":"Fujii Y.","year":"2012","unstructured":"Fujii Y.; Ito Y.; Harada K.H.; Hitomi T.; Koizumi A.; Haraguchi K.; Comparative survey of levels of chlorinated cyclodiene pesticides in breast milk from some cities of China, Korea and Japan. Chemosphere 2012,89(4),452-457","journal-title":"Chemosphere"},{"key":"ref=124","author":"Klaassen C.D.","year":"2013","unstructured":"Klaassen C.D.; Casarett L.J.; Doull J.;  Casarett and Doull\u2019s Toxicology: the Basic Science of Poisons 2013","journal-title":"Casarett and Doull\u2019s Toxicology: the Basic Science of Poisons"},{"key":"ref=125","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/0378-4274(85)90170-5","volume":"26","author":"Fishman B.E.","year":"1985","unstructured":"Fishman B.E.; Gianutsos G.; Inhibition of 4-aminobutyric acid (GABA) turnover by chlordane. Toxicol Lett 1985,26(2-3),219-223","journal-title":"Toxicol Lett"},{"key":"ref=126","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1080\/07315724.2002.10719223","author":"Bidlack W.R.","year":"2013","unstructured":"Bidlack W.R.;  Casarett  2013,289-290","journal-title":"Casarett"},{"key":"ref=127","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.cbi.2005.06.003","volume":"155","author":"Kretschmer X.C.","year":"2005","unstructured":"Kretschmer X.C.; Baldwin W.S.; CAR and PXR: xenosensors of endocrine disrupters? Chem Biol Interact 2005,155(3),111-128","journal-title":"Chem Biol Interact"},{"key":"ref=128","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1210\/er.2001-0038","volume":"23","author":"Kliewer S.A.","year":"2002","unstructured":"Kliewer S.A.; Goodwin B.; Willson T.M.; The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 2002,23(5),687-702","journal-title":"Endocr Rev"},{"key":"ref=129","year":"1980","unstructured":"Summary of Reported Pesticide Incidents Involving Chlordane EPA1980","journal-title":"Summary of Reported Pesticide Incidents Involving Chlordane"},{"key":"ref=130","first-page":"614","volume":"64","author":"Ortega P.","year":"1957","unstructured":"Ortega P.; Hayes W.J.; Jr.; Durham, W.F. Pathologic changes in the liver of rats after feeding low levels of various insecticides. AMA Arch Pathol 1957,64(6),614-622","journal-title":"AMA Arch Pathol"},{"key":"ref=131","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1080\/00039896.1992.9938365","volume":"47","author":"McConnachie P.R.","year":"1992","unstructured":"McConnachie P.R.; Zahalsky A.C.; Immune alterations in humans exposed to the termiticide technical chlordane. Arch Environ Health 1992,47(4),295-301","journal-title":"Arch Environ Health"},{"key":"ref=132","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/0300-483X(74)90030-4","volume":"2","author":"den Tonkelaar E.M.","year":"1974","unstructured":"den Tonkelaar E.M.; van Esch G.J.; No-effect levels of organochlorine pesticides based on induction of microsomal liver enzymes in short-term toxicity experiments. Toxicology 1974,2(4),371-380","journal-title":"Toxicology"},{"key":"ref=133","first-page":"1","volume":"79","year":"2001","unstructured":"W.H.O. Some thyrotropic agents. IARC Monogr Eval Carcinog Risks Hum 2001,79,1-725","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"ref=134","first-page":"2447","volume":"52","author":"Cantor K.P.","year":"1992","unstructured":"Cantor K.P.; Blair A.; Everett G.; Gibson R.; Burmeister L.F.; Brown L.M.; Schuman L.; Dick F.R.; Pesticides and other agricultural risk factors for non-Hodgkin\u2019s lymphoma among men in Iowa and Minnesota. Cancer Res 1992,52(9),2447-2455","journal-title":"Cancer Res"},{"key":"ref=135","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1158\/1055-9965.EPI-05-0556","volume":"15","author":"Colt J.S.","year":"2006","unstructured":"Colt J.S.; Davis S.; Severson R.K.; Lynch C.F.; Cozen W.; Camann D.; Engels E.A.; Blair A.; Hartge P.; Residential insecticide use and risk of non-Hodgkin\u2019s lymphoma. Cancer Epidemiol Biomarkers Prev 2006,15(2),251-257","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref=136","doi-asserted-by":"publisher","first-page":"2767","DOI":"10.1002\/ijc.23005","volume":"121","author":"Spinelli J.J.","year":"2007","unstructured":"Spinelli J.J.; Ng C.H.; Weber J.P.; Connors J.M.; Gascoyne R.D.; Lai A.S.; Brooks-Wilson A.R.; Le N.D.; Berry B.R.; Gallagher R.P.; Organochlorines and risk of non-Hodgkin lymphoma. Int J Cancer 2007,121(12),2767-2775","journal-title":"Int J Cancer"},{"key":"ref=137","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1289\/ehp.6726","volume":"112","author":"Quintana P.J.","year":"2004","unstructured":"Quintana P.J.; Delfino R.J.; Korrick S.; Ziogas A.; Kutz F.W.; Jones E.L.; Laden F.; Garshick E.; Adipose tissue levels of organochlorine pesticides and polychlorinated biphenyls and risk of non-Hodgkin\u2019s lymphoma. Environ Health Perspect 2004,112(8),854-861","journal-title":"Environ Health Perspect"},{"key":"ref=138","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.3892\/ijo.9.6.1139","volume":"9","author":"Hardell L.","year":"1996","unstructured":"Hardell L.; Liljegren G.; Lindstrom G.; Vanbavel B.; Broman K.; Fredrikson M.; Hagberg H.; Nordstrom M.; Johansson B.; Increased concentrations of chlordane in adipose tissue from non-Hodgkin\u2019s lymphoma patients compared with controls without a malignant disease. Int J Oncol 1996,9(6),1139-1142","journal-title":"Int J Oncol"},{"key":"ref=139","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1002\/ijc.22258","volume":"120","author":"Purdue M.P.","year":"2007","unstructured":"Purdue M.P.; Hoppin J.A.; Blair A.; Dosemeci M.; Alavanja M.C.; Occupational exposure to organochlorine insecticides and cancer incidence in the agricultural health study. Int J Cancer 2007,120(3),642-649","journal-title":"Int J Cancer"},{"key":"ref=140","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.biopha.2007.04.006","volume":"61","author":"Hardell L.","year":"2007","unstructured":"Hardell L.; Carlberg M.; Hardell K.; Bj\u00f6rnfoth H.; Wickbom G.; Ionescu M.; van Bavel B.; Lindstr\u00f6m G.; Decreased survival in pancreatic cancer patients with high concentrations of organochlorines in adipose tissue. Biomed Pharmacother 2007,61(10),659-664","journal-title":"Biomed Pharmacother"},{"key":"ref=141","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1179\/oeh.2005.11.2.123","volume":"11","author":"Mills P.K.","year":"2005","unstructured":"Mills P.K.; Yang R.; Breast cancer risk in Hispanic agricultural workers in California. Int J Occup Environ Health 2005,11(2),123-131","journal-title":"Int J Occup Environ Health"},{"key":"ref=142","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1126\/science.118.3060.213","volume":"118","author":"Ingle L.","year":"1953","unstructured":"Ingle L.; The toxicity of chlordane vapors. Science 1953,118(3060),213-214","journal-title":"Science"},{"key":"ref=143","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/BF01701883","volume":"43","author":"Khasawinah A.M.","year":"1989","unstructured":"Khasawinah A.M.; Chlordane residues in rat and monkey tissues following subchronic inhalation exposure to technical chlordane. Bull Environ Contam Toxicol 1989,43(3),459-466","journal-title":"Bull Environ Contam Toxicol"},{"key":"ref=144","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0272-0590(86)90246-0","volume":"6","author":"Johnson K.W.","year":"1986","unstructured":"Johnson K.W.; Holsapple M.P.; Munson A.E.; An immunotoxicological evaluation of gamma-chlordane. Fundam Appl Toxicol 1986,6(2),317-326","journal-title":"Fundam Appl Toxicol"},{"key":"ref=145","first-page":"159","volume":"7","author":"Truhaut R.","year":"1974","unstructured":"Truhaut R.; Gak C.; Modality and mechanism of the toxic action of organochlorine insecticides. I. Comparative study of the acute toxic effects on the hamster and the rat. Eur J Toxicol Environ Hyg 1974,7(3),159-166","journal-title":"Eur J Toxicol Environ Hyg"},{"key":"ref=146","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/S0041-008X(71)80015-7","volume":"18","author":"Casterline J.L.","year":"1971","unstructured":"Casterline J.L.; Jr.; Williams, C.H.; Keys, J.; Taylor, M.J. The effect of 28-day pesticide feeding on serum and tissue enzyme activities of rats fed diets of varying casein content. Toxicol Appl Pharmacol 1971,18(3),607-618","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref=147","first-page":"197","volume":"7","author":"Ambrose A.M.","year":"1953","unstructured":"Ambrose A.M.; Christensen H.E.; Robbins D.J.; Rather L.J.; Toxicological and pharmacological studies on chlordane. AMA Arch Ind Hyg Occup Med 1953,7(3),197-210","journal-title":"AMA Arch Ind Hyg Occup Med"},{"key":"ref=148","year":"2001","unstructured":"The 12 Initial POPs under the Stockholm Convention Stockholm ConventionAvailable at: \n             ext-link-type=\"uri\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"chm.pops.int\/TheConvention\/ThePOPs\/The12InitialPOPs\/t\nabid\/296\/Default.aspx\">chm.pops.int\/TheConvention\/ThePOPs\/The12InitialPOPs\/t\nabid\/296\/Default.aspx2001","journal-title":"The 12 Initial POPs under the Stockholm Convention"},{"key":"ref=149","doi-asserted-by":"publisher","first-page":"692","DOI":"10.2307\/2668517","volume":"95","author":"Lallas P.L.","year":"2001","unstructured":"Lallas P.L.; The Stockholm Convention on persistent organic pollutants. Am J Int Law 2001,95(3),692-708","journal-title":"Am J Int Law"},{"key":"ref=150","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1515\/intox-2016-0012","volume":"9","author":"Jayaraj R.","year":"2016","unstructured":"Jayaraj R.; Megha P.; Sreedev P.; Organochlorine pesticides, their toxic effects on living organisms and their fate in the environment. Interdiscip Toxicol 2016,9(3-4),90-100","journal-title":"Interdiscip Toxicol"},{"key":"ref=151","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1289\/ehp.0901321","volume":"118","author":"Ruzzin J.","year":"2010","unstructured":"Ruzzin J.; Petersen R.; Meugnier E.; Madsen L.; Lock E.J.; Lillefosse H.; Ma T.; Pesenti S.; Sonne S.B.; Marstrand T.T.; Malde M.K.; Du Z.Y.; Chavey C.; Fajas L.; Lundebye A.K.; Brand C.L.; Vidal H.; Kristiansen K.; Fr\u00f8yland L.; Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 2010,118(4),465-471","journal-title":"Environ Health Perspect"},{"key":"ref=152","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025170","volume":"6","author":"Ibrahim M.M.","year":"2011","unstructured":"Ibrahim M.M.; Fj\u00e6re E.; Lock E.J.; Naville D.; Amlund H.; Meugnier E.; Le Magueresse Battistoni B.; Fr\u00f8yland L.; Madsen L.; Jessen N.; Lund S.; Vidal H.; Ruzzin J.; Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. PLoS One 2011,6(9)","journal-title":"PLoS One"},{"key":"ref=153","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.atherosclerosis.2011.04.044","volume":"218","author":"Min J.Y.","year":"2011","unstructured":"Min J.Y.; Cho J.S.; Lee K.J.; Park J.B.; Park S.G.; Kim J.Y.; Min K.B.; Potential role for organochlorine pesticides in the prevalence of peripheral arterial diseases in obese persons: results from the National Health and Nutrition Examination Survey 1999-2004. Atherosclerosis 2011,218(1),200-206","journal-title":"Atherosclerosis"},{"key":"ref=154","doi-asserted-by":"publisher","first-page":"622","DOI":"10.2337\/dc06-2190","volume":"30","author":"Lee D.H.","year":"2007","unstructured":"Lee D.H.; Lee I.K.; Jin S.H.; Steffes M.; Jacobs D.R.; Jr. Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diabetes Care 2007,30(3),622-628","journal-title":"Diabetes Care"},{"key":"ref=155","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/j.envint.2010.02.012","volume":"36","author":"Son H.K.","year":"2010","unstructured":"Son H.K.; Kim S.A.; Kang J.H.; Chang Y.S.; Park S.K.; Lee S.K.; Jacobs D.R.; Jr.; Lee, D.H. Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea. Environ Int 2010,36(5),410-414","journal-title":"Environ Int"},{"key":"ref=156","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.2337\/dc06-0543","volume":"29","author":"Lee D.H.","year":"2006","unstructured":"Lee D.H.; Lee I.K.; Song K.; Steffes M.; Toscano W.; Baker B.A.; Jacobs D.R.; Jr. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes Care 2006,29(7),1638-1644","journal-title":"Diabetes Care"},{"key":"ref=157","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.2337\/dc10-2303","volume":"34","author":"Airaksinen R.","year":"2011","unstructured":"Airaksinen R.; Rantakokko P.; Eriksson J.G.; Blomstedt P.; Kajantie E.; Kiviranta H.; Association between type 2 diabetes and exposure to persistent organic pollutants. Diabetes Care 2011,34(9),1972-1979","journal-title":"Diabetes Care"},{"key":"ref=158","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.2337\/dc10-2116","volume":"34","author":"Lee D.H.","year":"2011","unstructured":"Lee D.H.; Lind P.M.; Jacobs D.R.; Jr.; Salihovic, S.; van Bavel, B.; Lind, L. Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study. Diabetes Care 2011,34(8),1778-1784","journal-title":"Diabetes Care"},{"key":"ref=159","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1210\/er.2013-1084","volume":"35","author":"Lee D.H.","year":"2014","unstructured":"Lee D.H.; Porta M.; Jacobs D.R.; Jr.; Vandenberg, L.N. Chlorinated persistent organic pollutants, obesity, and type 2 diabetes. Endocr Rev 2014,35(4),557-601","journal-title":"Endocr Rev"},{"key":"ref=160","doi-asserted-by":"publisher","first-page":"E1061","DOI":"10.1210\/jc.2013-3935","volume":"99","author":"Gauthier M.S.","year":"2014","unstructured":"Gauthier M.S.; Rabasa-Lhoret R.; Prud\u2019homme D.; Karelis A.D.; Geng D.; van Bavel B.; Ruzzin J.; The metabolically healthy but obese phenotype is associated with lower plasma levels of persistent organic pollutants as compared to the metabolically abnormal obese phenotype. J Clin Endocrinol Metab 2014,99(6),E1061-E1066","journal-title":"J Clin Endocrinol Metab"},{"key":"ref=161","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1038\/nrendo.2011.56","volume":"7","author":"Alonso-Magdalena P.","year":"2011","unstructured":"Alonso-Magdalena P.; Quesada I.; Nadal A.; Endocrine disruptors in the etiology of type 2 diabetes mellitus. Nat Rev Endocrinol 2011,7(6),346-353","journal-title":"Nat Rev Endocrinol"},{"key":"ref=162","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.tiv.2010.10.015","volume":"25","author":"Howell G.","year":"2011","unstructured":"Howell G.; Mangum L.;  Toxicol In Vitro 2011,25(1),394-402","journal-title":"Toxicol In Vitro"},{"key":"ref=163","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.diabet.2007.09.004","volume":"34","author":"Antuna-Puente B.","year":"2008","unstructured":"Antuna-Puente B.; Feve B.; Fellahi S.; Bastard J.P.; Adipokines: the missing link between insulin resistance and obesity. Diabetes Metab 2008,34(1),2-11","journal-title":"Diabetes Metab"},{"key":"ref=164","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2337\/diab.46.1.3","volume":"46","author":"Boden G.","year":"1997","unstructured":"Boden G.; Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997,46(1),3-10","journal-title":"Diabetes"},{"key":"ref=165","doi-asserted-by":"publisher","first-page":"8033","DOI":"10.1021\/acs.est.5b00520","volume":"49","author":"Kim S.","year":"2015","unstructured":"Kim S.; Park J.; Kim H.J.; Lee J.J.; Choi G.; Choi S.; Kim S.; Kim S.Y.; Lee D.H.; Moon H.B.; Kim S.; Choi K.; Association between several persistent organic pollutants in serum and adipokine levels in breast milk among lactating women of Korea. Environ Sci Technol 2015,49(13),8033-8040","journal-title":"Environ Sci Technol"},{"key":"ref=166","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1002\/oby.20314","volume":"21","author":"Boeke C.E.","year":"2013","unstructured":"Boeke C.E.; Mantzoros C.S.; Hughes M.D.L.; Rifas-Shiman L.; S.; Villamor, E.; Zera, C.A.; Gillman, M.W. Differential associations of leptin with adiposity across early childhood. Obesity (Silver Spring) 2013,21(7),1430-1437","journal-title":"Obesity (Silver Spring)"},{"key":"ref=167","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1542\/peds.2008-0343","volume":"123","author":"Mantzoros C.S.","year":"2009","unstructured":"Mantzoros C.S.; Rifas-Shiman S.L.; Williams C.J.; Fargnoli J.L.; Kelesidis T.; Gillman M.W.; Cord blood leptin and adiponectin as predictors of adiposity in children at 3 years of age: a prospective cohort study. Pediatrics 2009,123(2),682-689","journal-title":"Pediatrics"},{"key":"ref=168","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1038\/oby.2006.155","volume":"14","author":"Miralles O.","year":"2006","unstructured":"Miralles O.; S\u00e1nchez J.; Palou A.; Pic\u00f3 C.; A physiological role of breast milk leptin in body weight control in developing infants. Obesity (Silver Spring) 2006,14(8),1371-1377","journal-title":"Obesity (Silver Spring)"},{"key":"ref=169","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11912-016-0528-7","volume":"18","author":"John G.K.","year":"2016","unstructured":"John G.K.; Mullin G.E.; The gut microbiome and obesity. Curr Oncol Rep 2016,18(7),45","journal-title":"Curr Oncol Rep"},{"key":"ref=170","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1038\/nature05414","volume":"444","author":"Turnbaugh P.J.","year":"2006","unstructured":"Turnbaugh P.J.; Ley R.E.; Mahowald M.A.; Magrini V.; Mardis E.R.; Gordon J.I.; An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006,444(7122),1027-1031","journal-title":"Nature"},{"key":"ref=171","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1038\/nature12506","volume":"500","author":"Le Chatelier E.","year":"2013","unstructured":"Le Chatelier E.; Nielsen T.; Qin J.; Prifti E.; Hildebrand F.; Falony G.; Almeida M.; Arumugam M.; Batto J.M.; Kennedy S.; Leonard P.; Li J.; Burgdorf K.; Grarup N.; J\u00f8rgensen T.; Brandslund I.; Nielsen H.B.; Juncker A.S.; Bertalan M.; Levenez F.; Pons N.; Rasmussen S.; Sunagawa S.; Tap J.; Tims S.; Zoetendal E.G.; Brunak S.; Cl\u00e9ment K.; Dor\u00e9 J.; Kleerebezem M.; Kristiansen K.; Renault P.; Sicheritz-Ponten T.; de Vos W.M.; Zucker J.D.; Raes J.; Hansen T.; Bork P.; Wang J.; Ehrlich S.D.; Pedersen O.; MetaHIT consortium. Richness of human gut microbiome correlates with metabolic markers. Nature 2013,500(7464),541-546","journal-title":"Nature"},{"key":"ref=172","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1096\/fasebj.29.1_supplement.850.2","volume":"29","author":"Tousignant K.","year":"2015","unstructured":"Tousignant K.; Uno J.; The effect of obesogens on the microbiota and systemic health in zebrafish. The FASEB J 2015,29(1),850-852","journal-title":"The FASEB J"},{"key":"ref=173","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/j.envpol.2016.08.039","volume":"218","author":"Lai K.P.","year":"2016","unstructured":"Lai K.P.; Chung Y.T.; Li R.; Wan H.T.; Wong C.K.C.; Bisphenol A alters gut microbiome: comparative metagenomics analysis. Environ Pollut 2016,218,923-930","journal-title":"Environ Pollut"},{"key":"ref=174","doi-asserted-by":"publisher","first-page":"396","DOI":"10.3389\/fcimb.2017.00396","volume":"7","author":"Rosenfeld C.S.","year":"2017","unstructured":"Rosenfeld C.S.; Gut dysbiosis in animals due to environmental chemical exposures. Front Cell Infect Microbiol 2017,7,396-396","journal-title":"Front Cell Infect Microbiol"},{"key":"ref=175","doi-asserted-by":"publisher","first-page":"2365","DOI":"10.1073\/pnas.0812600106","volume":"106","author":"Zhang H.","year":"2009","unstructured":"Zhang H.; DiBaise J.K.; Zuccolo A.; Kudrna D.; Braidotti M.; Yu Y.; Parameswaran P.; Crowell M.D.; Wing R.; Rittmann B.E.; Krajmalnik-Brown R.; Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci USA 2009,106(7),2365-2370","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref=176","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/oby.2009.167","volume":"18","author":"Schwiertz A.","year":"2010","unstructured":"Schwiertz A.; Taras D.; Sch\u00e4fer K.; Beijer S.; Bos N.A.; Donus C.; Hardt P.D.; Microbiota and SCFA in lean and overweight healthy subjects. Obesity (Silver Spring) 2010,18(1),190-195","journal-title":"Obesity (Silver Spring)"},{"key":"ref=177","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1038\/ijo.2011.153","volume":"36","author":"Million M.","year":"2012","unstructured":"Million M.; Maraninchi M.; Henry M.; Armougom F.; Richet H.; Carrieri P.; Valero R.; Raccah D.; Vialettes B.; Raoult D.; Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. Int J Obes 2012,36(6),817-825","journal-title":"Int J Obes"},{"key":"ref=178","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027773","volume":"6","author":"Lee H.S.","year":"2011","unstructured":"Lee H.S.; Lee J.C.; Lee I.K.; Moon H.B.; Chang Y.S.; Jacobs D.R.; Lee D.H.; Associations among organochlorine pesticides, Methanobacteriales, and obesity in Korean women. PLoS One 2011,6(11)","journal-title":"PLoS One"},{"key":"ref=179","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1002\/oby.20267","volume":"21","author":"Roos V.","year":"2013","unstructured":"Roos V.; R\u00f6nn M.; Salihovic S.; Lind L.; van Bavel B.; Kullberg J.; Johansson L.; Ahlstr\u00f6m H.; Lind P.M.; Circulating levels of persistent organic pollutants in relation to visceral and subcutaneous adipose tissue by abdominal MRI. Obesity (Silver Spring) 2013,21(2),413-418","journal-title":"Obesity (Silver Spring)"},{"key":"ref=180","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1016\/j.chemosphere.2006.10.033","volume":"67","author":"Hue O.","year":"2007","unstructured":"Hue O.; Marcotte J.; Berrigan F.; Simoneau M.; Dor\u00e9 J.; Marceau P.; Marceau S.; Tremblay A.; Teasdale N.; Plasma concentration of organochlorine compounds is associated with age and not obesity. Chemosphere 2007,67(7),1463-1467","journal-title":"Chemosphere"},{"key":"ref=181","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1289\/ehp.1205901","volume":"121","author":"Cupul-Uicab L.A.","year":"2013","unstructured":"Cupul-Uicab L.A.; Klebanoff M.A.; Brock J.W.; Longnecker M.P.; Prenatal exposure to persistent organochlorines and childhood obesity in the US collaborative perinatal project. Environ Health Perspect 2013,121(9),1103-1109","journal-title":"Environ Health Perspect"},{"key":"ref=182","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1210\/er.2011-1050","volume":"33","author":"Vandenberg L.N.","year":"2012","unstructured":"Vandenberg L.N.; Colborn T.; Hayes T.B.; Heindel J.J.; Jacobs D.R.; Lee D-H.; Shioda T.; Soto A.M.; vom Saal F.S.; Welshons W.V.; Zoeller R.T.; Myers J.P.; Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 2012,33(3),378-455","journal-title":"Endocr Rev"},{"key":"ref=183","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1093\/toxsci\/kfi106","volume":"85","author":"Croutch C.R.","year":"2005","unstructured":"Croutch C.R.; Lebofsky M.; Schramm K.W.; Terranova P.F.; Rozman K.K.; 2,3,7,8-Tetrachlorodibenzo-p-dioxin\n(TCDD) and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin\n(HxCDD) alter body weight by decreasing insulin-like\ngrowth factor I (IGF-I) signaling.  Toxicol Sci 2005,85(1),560-571","journal-title":"Toxicol Sci"},{"key":"ref=184","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.envpol.2016.11.028","volume":"222","author":"Wang D.","year":"2017","unstructured":"Wang D.; Wang X.; Zhang P.; Wang Y.; Zhang R.; Yan J.; Zhou Z.; Zhu W.; The fate of technical-grade chlordane in mice fed a high-fat diet and its roles as a candidate obesogen. Environ Pollut 2017,222,532-542","journal-title":"Environ Pollut"},{"key":"ref=185","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1093\/jnci\/djn101","volume":"100","author":"McGlynn K.A.","year":"2008","unstructured":"McGlynn K.A.; Quraishi S.M.; Graubard B.I.; Weber J.P.; Rubertone M.V.; Erickson R.L.; Persistent organochlorine pesticides and risk of testicular germ cell tumors. J Natl Cancer Inst 2008,100(9),663-671","journal-title":"J Natl Cancer Inst"},{"key":"ref=186","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1128\/AEM.38.3.544-546.1979","volume":"38","author":"Aragozzini F.","year":"1979","unstructured":"Aragozzini F.; Ferrari A.; Pacini N.; Gualandris R.; Indole-3-lactic acid as a tryptophan metabolite produced by Bifidobacterium spp. Appl Environ Microbiol 1979,38(3),544-546","journal-title":"Appl Environ Microbiol"},{"key":"ref=187","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1006\/taap.1994.1123","volume":"126","author":"Cassidy R.A.","year":"1994","unstructured":"Cassidy R.A.; Vorhees C.V.; Minnema D.J.; Hastings L.; The effects of chlordane exposure during pre- and postnatal periods at environmentally relevant levels on sex steroid-mediated behaviors and functions in the rat. Toxicol Appl Pharmacol 1994,126(2),326-337","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref=188","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0306-3623(87)90244-8","volume":"18","author":"Haake J.","year":"1987","unstructured":"Haake J.; Kelley M.; Keys B.; Safe S.; The effects of organochlorine pesticides as inducers of testosterone and benzo[a]pyrene hydroxylases. Gen Pharmacol 1987,18(2),165-169","journal-title":"Gen Pharmacol"},{"key":"ref=189","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/0013-9351(84)90128-2","volume":"35","author":"Cranmer J.M.","year":"1984","unstructured":"Cranmer J.M.; Cranmer M.F.; Goad P.T.; Prenatal chlordane exposure: effects on plasma corticosterone concentrations over the lifespan of mice. Environ Res 1984,35(1),204-210","journal-title":"Environ Res"},{"key":"ref=190","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1111\/j.1467-789X.2004.00152.x","volume":"5","author":"Mayes J.S.","year":"2004","unstructured":"Mayes J.S.; Watson G.H.; Direct effects of sex steroid hormones on adipose tissues and obesity. Obes Rev 2004,5(4),197-216","journal-title":"Obes Rev"}],"container-title":["Current Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0929867327666200121122208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/178469\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0929867327666200121122208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T18:34:36Z","timestamp":1660070076000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/178469\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":190,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/0929867327666200121122208","relation":{},"ISSN":["0929-8673"],"issn-type":[{"value":"0929-8673","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2019-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-09","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}