{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:50:34Z","timestamp":1740142234348,"version":"3.37.3"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"7","funder":[{"DOI":"10.13039\/501100001871","name":"Portuguese Foundation for Science and Technolog","doi-asserted-by":"publisher","award":["UIDB\/04423\/2020","UIDP\/04423\/2020","POCI-01-0124-FEDER-016845","POCI-01-0145-FEDER\/031774\/ 2017"],"award-info":[{"award-number":["UIDB\/04423\/2020","UIDP\/04423\/2020","POCI-01-0124-FEDER-016845","POCI-01-0145-FEDER\/031774\/ 2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CTMC"],"published-print":{"date-parts":[[2021,4,26]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>Molecular phylogenetic algorithms frequently disagree with the approaches\nconsidering reproductive compatibility and morphological criteria for species delimitation. The\nquestion stems if the resulting species boundaries from molecular, reproductive and\/or morphological\ndata are definitively not reconcilable; or if the existing phylogenetic methods are not sensitive\nenough to agree morphological and genetic variation in species delimitation.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title> Objectives :<\/jats:title>\n<jats:p>We propose DISTATIS as an integrative framework to combine alignment-based (AB)\nand alignment-free (AF) distance matrices from ITS2 sequences\/structures to shed light whether\nGelasinospora and Neurospora are sister but independent genera.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p> We aimed at addressing this standing issue by harmonizing genus-specific classification\nbased on their ascospore morphology and ITS2 molecular data. To validate our proposal, three phylogenetic\napproaches: i) traditional alignment-based, ii) alignment-free and iii) novel distance integrative\n(DI)-based were comparatively evaluated on a set of Gelasinospora and Neurospora species.\nAll considered species have been extensively characterized at both the morphological and reproductive\nlevels and there are known incongruences between their ascospore morphology and\nmolecular data that hampers genus-specific delimitation.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p> Traditional AB phylogenetic analyses fail at resolving the Gelasinospora and Neurospora\ngenera into independent monophyletic clades following ascospore morphology criteria. In contrast,\nAF and DI approaches produced phylogenetic trees that could properly delimit the expected monophyletic\nclades.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions:<\/jats:title>\n<jats:p>The DI approach outperformed the AF one in the sense that it could also divide the\nNeurospora species according to their reproduction mode.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1568026621666210113164605","type":"journal-article","created":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T04:56:11Z","timestamp":1610600171000},"page":"599-611","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["DISTATIS: A Promising Framework to Integrate Distance Matrices in Molecular Phylogenetics"],"prefix":"10.2174","volume":"21","author":[{"given":"Guillermin","family":"Ag\u00fcero-Chapin","sequence":"first","affiliation":[{"name":"CIMAR\/CIIMAR, Centro Interdisciplinar de Investigacao Marinha e Ambiental & Departamento de Biologia, Faculdade de Ciencias, Universidade do Porto, Porto, Portugal"}]},{"given":"Yuliana","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Departamento de Quimica y Ciencias Exactas, Seccion de Fisicoquimica y Matematicas, Universidad Tecnica Particular de Loja (UTPL), Loja, Ecuador"}]},{"given":"Aminael","family":"S\u00e1nchez-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Biologicas, Seccion de Biotecnologia y Produccion, Universidad Tecnica Particular de Loja, Loja, Ecuador"}]},{"given":"Reinaldo","family":"Molina-Ruiz","sequence":"additional","affiliation":[{"name":"Centro de Bioactivos Quimicos (CBQ), Universidad Central \u00a8Marta Abreu\u00a8 de Las Villas, Santa Clara, Cuba"}]},{"given":"Oscar","family":"Vivanco","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Biologicas, Seccion de Biotecnologia y Produccion, Universidad Tecnica Particular de Loja, Loja, Ecuador"}]},{"given":"Agostinho","family":"Antunes","sequence":"additional","affiliation":[{"name":"CIMAR\/CIIMAR, Centro Interdisciplinar de Investigacao Marinha e Ambiental & Departamento de Biologia, Faculdade de Ciencias, Universidade do Porto, Porto, Portugal"}]}],"member":"965","container-title":["Current Topics in Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/190275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/190275\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/190275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T12:13:17Z","timestamp":1619698397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/190275\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,26]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,4,26]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1568026621666210113164605","relation":{},"ISSN":["1568-0266"],"issn-type":[{"type":"print","value":"1568-0266"}],"subject":[],"published":{"date-parts":[[2021,4,26]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2020-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-16","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}