{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:46:56Z","timestamp":1761583616318,"version":"build-2065373602"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"4","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CNANO"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>The past years have witnessed a persistent deterioration of sexual health, especially among young adults. The most concerning\nproblems are sexually transmitted diseases and non-planned pregnancies that cost millions of dollars in healthcare. Sexually transmitted\ndiseases are usually represented by cutaneous signs which may provide a portal of entry for the transmission of other infections, such as\nHIV. Skin is a widely used route of delivery of drugs locally, and also potentially promising pathway for systemic targeting. Skin contributes\nto the physical and chemical protection of the body, providing an important barrier against topical drug administration. However,\nit may be overcome by nanotechnology-based systems, especially in skin diseases, reducing the side effects. Different approaches have\nbeen focused on nanotechnology, not only in the treatment of sexually transmitted diseases, but also in diagnostics and prevention of\nthese infections. The present paper highlights recent advances in the nanotechnology-based systems for the diagnostic, prevention and\ntopical treatment of sexually transmitted diseases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2174\/157341312801784348","type":"journal-article","created":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T20:25:21Z","timestamp":1342643121000},"page":"486-490","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Topical Targeting Therapies for Sexually Transmitted Diseases"],"prefix":"10.2174","volume":"8","author":[{"given":"Tatiana","family":"Andreani","sequence":"first","affiliation":[]},{"given":"Ana","family":"Sofia Macedo","sequence":"additional","affiliation":[]},{"given":"Sandra","family":"F. Ferreira","sequence":"additional","affiliation":[]},{"given":"Amelia","family":"M. Silva","sequence":"additional","affiliation":[]},{"given":"Aristoteles","family":"Rosmaninho","sequence":"additional","affiliation":[]},{"given":"Eliana","family":"B. Souto","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Technology, Faculty of Health Sciences, UFP, Rua Carlos da Maia, 296, P-4200-150 Porto, Portugal.,Portugal"}]}],"member":"965","container-title":["Current Nanoscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/157341312801784348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/100593\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/157341312801784348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:42:46Z","timestamp":1761583366000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/100593\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/157341312801784348","relation":{},"ISSN":["1573-4137"],"issn-type":[{"type":"print","value":"1573-4137"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Double blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-07-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}