{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T10:40:26Z","timestamp":1735296026864,"version":"3.32.0"},"reference-count":34,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T00:00:00Z","timestamp":1543536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["benthamopenarchives.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOPARAJ"],"published-print":{"date-parts":[[2018,11,30]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In veterinary medicine, an increasing incidence of neoplastic diseases has been followed by a growth in the use of chemotherapeutic drugs, often associated with opportunistic infections.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                        This study aimed to assess the prevalence of gastrointestinal parasites in dogs undergoing antineoplastic chemotherapy in the Lisbon Metropolitan Area, as well as their evolution throughout the protocol and respective effects of chemotherapy on dogs\u2019 lifestyle.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Faecal samples were collected in a group of 30 dogs being treated for neoplastic diseases under different protocols, previous (G1) and during chemotherapy (G2). In total, 60 samples were analysed by Willis flotation, natural sedimentation, Baermann technique and faecal smear stained with Ziehl-Neelsen. A survey to characterize animal lifestyles and deworming care were also conducted with dog\u2019s tutors.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In total, there were two positive samples for the protozoan <jats:italic>Giardia<\/jats:italic> sp., one of which is in association with the nematode <jats:italic>Toxascaris leonina<\/jats:italic>. The two dogs only obtained positive results during chemotherapy (G2). An overall prevalence of gastrointestinal parasitic diseases of 6.7%, in G2, and 0%, in G1, was obtained.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The low parasite prevalence has not allowed the evaluation of an association between the use of antineoplastic compounds and infections by gastrointestinal parasites. However, it was concluded that the studied groups were efficiently dewormed, as well as they did not experience any obvious changes in their parasitological component and its lifestyle.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874421401806010096","type":"journal-article","created":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T09:29:07Z","timestamp":1543829347000},"page":"96-105","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Antineoplastic Chemotherapy and its Effects on the Gastrointestinal Parasitism of the Dog"],"prefix":"10.2174","volume":"6","author":[{"given":"Jo\u00e3o Lory","family":"Costa","sequence":"first","affiliation":[]},{"given":"Ana Margarida","family":"Alho","sequence":"additional","affiliation":[]},{"given":"L\u00eddia","family":"Gomes","sequence":"additional","affiliation":[]},{"given":"Ana","family":"Eiras","sequence":"additional","affiliation":[]},{"given":"Telmo","family":"Nunes","sequence":"additional","affiliation":[]},{"given":"Gon\u00e7alo","family":"Vicente","sequence":"additional","affiliation":[]},{"given":"Patr\u00edcia","family":"Lopes","sequence":"additional","affiliation":[]},{"given":"Lu\u00eds","family":"Madeira de Carvalho","sequence":"additional","affiliation":[]}],"member":"965","reference":[{"key":"refR1","unstructured":"Bowman DD. \n                    Georgis\u2019 parasitology for veterinarians  10th ed. \n                    \n                    \n                    \n                    2014."},{"key":"refR2","unstructured":"Urquhart GM, Armour J, Duncan JL, Dunn AM, Jennings FW. \n                    Veterinary Parasitology  2nd ed. \n                    \n                    \n                    \n                    1996."},{"key":"refR3","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1939-1676.2011.0695.x","volume":"25","author":"Fleming J.M.","year":"2011","unstructured":"Fleming JM, Creevy KE, Promislow DEL. \n                    Mortality in north american dogs from 1984 to 2004: An investigation into age-, size-, and breed-related causes of death. \n                    J Vet Intern Med  \n                    2011; \n                    25\n                    (2)\n                    : 187-98.","journal-title":"J. Vet. Intern. Med."},{"key":"refR4","unstructured":"European Scientific Counsel Animal Parasites (ESCCAP) 2018. Guideline 1: Worm Control in Dogs and Cats (3rd ed.). 2018."},{"key":"refR5","unstructured":"European Scientific Counsel Animal Parasites (ESCCAP) 2018. Guideline 6: Control of intestinal protozoa in dogs and cats (2nd ed.). 2018."},{"key":"refR6","unstructured":"Thienpont D, Rochette F, Vanparijs OFJ. \n                    Diagn\u00f3stico de las helmintiasis por medio del examen coprol\u00f3gico  2nd ed. \n                    \n                    \n                    \n                    1986."},{"key":"refR7","first-page":"28","volume":"1","author":"Alho A.M.","year":"2013","unstructured":"Alho AM, Nabais J, Madeira de Carvalho LM. \n                    A import\u00e2ncia da T\u00e9cnica de Baermann na cl\u00ednica de pequenos animais. \n                    Cl\u00ednica Animal  \n                    2013; \n                    1\n                    (3)\n                    : 28-31.","journal-title":"Cl\u00ednica Animal"},{"key":"refR8","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1136\/jcp.38.12.1337","volume":"38","author":"Casemore D.P.","year":"1985","unstructured":"Casemore DP, Armstrong M, Sands RL. \n                    Laboratory diagnosis of cryptosporidiosis. \n                    J Clin Pathol  \n                    1985; \n                    38\n                    (12)\n                    : 1337-41.","journal-title":"J. Clin. Pathol."},{"key":"refR9","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1186\/1756-3305-7-429","volume":"7","author":"Smith A.F.","year":"2014","unstructured":"Smith AF, Semeniuk CA, Kutz SJ, Massolo A. \n                    Dog-walking behaviours affect gastrointestinal parasitism in park-attending dogs. \n                    Parasit Vectors  \n                    2014; \n                    7\n                    (1)\n                    : 429.","journal-title":"Parasit. Vectors"},{"key":"refR10","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.vetpar.2011.02.003","volume":"179","author":"Ferreira F.S.","year":"2011","unstructured":"Ferreira FS, Pereira-Baltasar P, Parreira R, et al. \n                    Intestinal parasites in dogs and cats from the district of \u00c9vora, Portugal. \n                    Vet Parasitol  \n                    2011; \n                    179\n                    (1-3)\n                    : 242-5.","journal-title":"Vet. Parasitol."},{"key":"refR11","unstructured":"Lebre FLMCR. \n                    \n                 Survey of gastrointestinal parasites and their zoonotic impact in shelter dogs from Lisbon. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2011."},{"key":"refR12","first-page":"29","volume":"17","author":"Pitaes A.","year":"2015","unstructured":"Pitaes A, Nunes T, Fernandes A, Madeira de Carvalho LM. \n                    Papel do parasitismo por Giardia sp. em sistemas de produ\u00e7\u00e3o canina - Resultados em canis de cria\u00e7\u00e3o na regi\u00e3o de Viseu, Portugal. \n                    Vet Med  \n                    2015; \n                    17\n                    (98)\n                    : 29-36.","journal-title":"Vet. Med."},{"key":"refR13","unstructured":"Braga MIFL. \n                    \n                 Prevalence and seasonal variation of gastrointestinal, cardiovascular and hematic parasites in dogs from Beja district, Portugal. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2017."},{"key":"refR14","doi-asserted-by":"publisher","first-page":"5984086","DOI":"10.1155\/2017\/5984086","volume":"2017","author":"Ferreira A.","year":"2017","unstructured":"Ferreira A, Alho AM, Otero D, et al. \n                    Urban dog parks as sources of canine parasites: Contamination rates and pet owner behaviours in Lisbon, Portugal. \n                    J Environ Public Health  \n                    2017; \n                    2017\n                    : 5984086.","journal-title":"J. Environ. Public Health"},{"key":"refR15","unstructured":"F\u00e9lix LIB. \n                    \n                 Gastrointestinal and cardiopulmonary parasitosis in dogs. Epidemiological study on shelters of Portugal Continental. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2015."},{"key":"refR16","unstructured":"Melo ACMS. \n                    \n                 Gastrointestinal and pulmonary parasites of dogs and cats from western region of Continental Portugal. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2017."},{"key":"refR17","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.prevetmed.2015.09.006","volume":"122","author":"Matos M.","year":"2015","unstructured":"Matos M, Alho AM, Owen SP, Nunes T, Madeira de Carvalho L. \n                    Parasite control practices and public perception of parasitic diseases: A survey of dog and cat owners. \n                    Prev Vet Med  \n                    2015; \n                    122\n                    (1-2)\n                    : 174-80.","journal-title":"Prev. Vet. Med."},{"key":"refR18","unstructured":"Morgado GM. \n                    \n                 Internal parasites and deworm frequency of dogs in Vila Franca de Xira, Portugal. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2016."},{"key":"refR19","unstructured":"Nabais PMMD. \n                    \n                 Control of gastrointestinal helminthosis in dogs. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2008."},{"key":"refR20","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.vetpar.2009.07.041","volume":"166","author":"Gates M.C.","year":"2009","unstructured":"Gates MC, Nolan TJ. \n                    Endoparasite prevalence and recurrence across different age groups of dogs and cats. \n                    Vet Parasitol  \n                    2009; \n                    166\n                    (1-2)\n                    : 153-8.","journal-title":"Vet. Parasitol."},{"key":"refR21","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1053\/j.tcam.2009.02.004","volume":"24","author":"Vail D.M.","year":"2009","unstructured":"Vail DM. \n                    Supporting the veterinary cancer patient on chemotherapy: Neutropenia and gastrointestinal toxicity. \n                    Top Companion Anim Med  \n                    2009; \n                    24\n                    (3)\n                    : 122-9.","journal-title":"Top. Companion Anim. Med."},{"key":"refR22","first-page":"1","volume":"24","author":"Faro A.M.","year":"2008","unstructured":"Faro AM, Daleck CR, Santana \u00c1E, Nardi AB, Motta FR, Eurides D. \n                    Haematological assessment in dogs undergoing antineoplastic treatment with vincristine sulphate, prednisone and cyclophosphamide -experimental study. \n                    Ars Vet  \n                    2008; \n                    24\n                    (1)\n                    : 1-8.","journal-title":"Ars Vet."},{"key":"refR23","unstructured":"Lima FON. \n                    \n                 Contribution to the study of chemotherapy associated immunosupression in dogs. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2011."},{"key":"refR24","first-page":"124","volume":"2","author":"Ganesan G.","year":"2016","unstructured":"Ganesan G. \n                    Eosinophilia as an important indicator of hookworm infection. \n                    World J Pharm Med Res  \n                    2016; \n                    2\n                    (3)\n                    : 124-6.","journal-title":"World J Pharm Med Res"},{"key":"refR25","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.1007\/s00436-017-5560-5","volume":"116","author":"Berahmat R.","year":"2017","unstructured":"Berahmat R, Mahami-Oskouei M, Rezamand A, et al. \n                    \n                        Cryptosporidium infection in children with cancer undergoing chemotherapy: How important is the prevention of opportunistic parasitic infections in patients with malignancies? \n                    Parasitol Res  \n                    2017; \n                    116\n                    (9)\n                    : 2507-15.","journal-title":"Parasitol. Res."},{"key":"refR26","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1590\/1519-6984.175364","volume":"78","author":"Jeske S.","year":"2018","unstructured":"Jeske S, Bianchi TF, Moura MQ, et al. \n                    Intestinal parasites in cancer patients in the South of Brazil. \n                    Braz J Biol  \n                    2018; \n                    78\n                    (3)\n                    : 574-8.","journal-title":"Braz. J. Biol."},{"key":"refR27","first-page":"42","volume":"3","author":"Kazemi E.","year":"2014","unstructured":"Kazemi E, Tavalla M, Maraghi S, Sharafkhani R. \n                    Frequency of intestinal parasites among immunosupressed patients in undergoing chemotherapy in Khuzestan Province, Southwest Iran. \n                    Int J Anal Pharm Biomed Sci  \n                    2014; \n                    3\n                    (4)\n                    : 42-6.","journal-title":"Int J Anal Pharm Biomed Sci"},{"key":"refR28","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1093\/tropej\/45.4.241","volume":"45","author":"Menon B.S.","year":"1999","unstructured":"Menon BS, Abdullah MS, Mahamud F, Singh B. \n                    Intestinal parasites in Malaysian children with cancer. \n                    J Trop Pediatr  \n                    1999; \n                    45\n                    (4)\n                    : 241-2.","journal-title":"J. Trop. Pediatr."},{"key":"refR29","first-page":"280","volume":"13","author":"Pacheco F.T.F.","year":"2014","unstructured":"Pacheco FTF, Silva RKNR, Mendes AVA, et al. \n                    Infec\u00e7\u00e3o por Giardia duodenalis e outros enteroparasitos em crian\u00e7as com c\u00e2ncer e crian\u00e7as de creche em Salvador, Bahia. \n                    Rev Mex Cienc Med Biol  \n                    2014; \n                    13\n                    (3)\n                    : 280-6.","journal-title":"Rev. Mex. Cienc. Med. Biol."},{"key":"refR30","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3923\/jp.2014.55.63","volume":"9","author":"Sanad M.M.","year":"2014","unstructured":"Sanad MM, Thagfan FA, Al Olayan EM, et al. \n                    Opportunistic coccidian parasites among Saudi cancer patients presenting with diarrhoea: Prevalence and immune status. \n                    Res J Parasitol  \n                    2014; \n                    9\n                    (2)\n                    : 55-63.","journal-title":"Res J Parasitol"},{"key":"refR31","first-page":"170","volume":"27","author":"Silva L.P.","year":"2011","unstructured":"Silva LP, Silva RMG, Fernandes NA, Oliveira JAA. \n                    Parasitos e comensais intestinais em pacientes neopl\u00e1sicos submetidos \u00e0 quimioterapia. \n                    Biosci J  \n                    2011; \n                    27\n                    (1)\n                    : 170-7.","journal-title":"Biosci. J."},{"key":"refR32","doi-asserted-by":"publisher","first-page":"63","DOI":"10.5799\/jmid.vi.328785","volume":"7","author":"Uysal S.","year":"2017","unstructured":"Uysal S, \u00d6zt\u00fcrk EA, Tunali V, et al. \n                    Intestinal parasitic infectons in patients leukemic patients with diarrhoea. \n                    J Microbiol Infect Dis  \n                    2017; \n                    7\n                    (2)\n                    : 63-6.","journal-title":"J Microbiol Infect Dis"},{"key":"refR33","unstructured":"Couto C. \n                    Oncology.\n                    Small Animal Internal Medicine  5th ed. \n                    \n                    \n                    \n                    \n                    2015; \n                    1126-200."},{"key":"refR34","doi-asserted-by":"crossref","unstructured":"Costa JMPSL. \n                    \n                 Antineoplastic chemotherapy and its effects on the gastrointestinal parasitism of the dog. MSc dissertation, Faculty of Veterinary Medicine, Lisbon University 2018.","DOI":"10.2174\/1874421401806010096"}],"container-title":["The Open Parasitology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/benthamopenarchives.com\/contents\/pdf\/TOPARAJ\/TOPARAJ-6-96.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/benthamopenarchives.com\/contents\/fulltext-xml\/TOPARAJ\/TOPARAJ-6-96.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/benthamopenarchives.com\/contents\/pdf\/TOPARAJ\/TOPARAJ-6-96.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T09:42:41Z","timestamp":1735292561000},"score":1,"resource":{"primary":{"URL":"https:\/\/benthamopenarchives.com\/abstract.php?ArticleCode=TOPARAJ-6-96"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,30]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,11,30]]}},"alternative-id":["TOPARAJ-6-96"],"URL":"https:\/\/doi.org\/10.2174\/1874421401806010096","relation":{},"ISSN":["1874-4214"],"issn-type":[{"type":"print","value":"1874-4214"}],"subject":[],"published":{"date-parts":[[2018,11,30]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2018-7-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-18","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}