{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:13:03Z","timestamp":1771045983250,"version":"3.50.1"},"reference-count":16,"publisher":"Japan Neurosurgical Society","issue":"0","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.2176\/jns-nmc.2025-0286","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T22:10:02Z","timestamp":1770847802000},"page":"33-36","source":"Crossref","is-referenced-by-count":0,"title":["Adult Medullary Diffuse Midline Glioma Presenting with Orthostatic Hypotension: A Case Report"],"prefix":"10.2176","volume":"13","author":[{"given":"Mizuho","family":"INOUE","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Tokyo General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"MORI","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"NUMAZAWA","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadayoshi","family":"WATANABE","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"971","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1) L\u00f3pez-P\u00e9rez CA, Franco-Mojica X, Villanueva-Gaona R, et al. Adult diffuse midline gliomas H3 K27-altered: review of a redefined entity. J Neurooncol. 2022;158 (3):369-78. doi: 10.1007\/s11060-022-04024-5","DOI":"10.1007\/s11060-022-04024-5"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2) Yekula A, Gupta M, Coley N, et al. Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: case report and review of the literature. Int J Surg Case Rep. 2020;68:124-8. doi: 10.1016\/j.ijscr.2020.02.046","DOI":"10.1016\/j.ijscr.2020.02.046"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3) Meyronet D, Esteban-Mader M, Bonnet C, et al. Characteristics of H3 K27M-mutant gliomas in adults. Neuro Oncol. 2017;19 (8):1127-34. doi: 10.1093\/neuonc\/now274","DOI":"10.1093\/neuonc\/now274"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4) Freeman R, Abuzinadah AR, Gibbons C, et al. Orthostatic hypotension: JACC state-of-the-art review. J Am Coll Cardiol. 2018;72 (11):1294-309. doi: 10.1016\/j.jacc.2018.05.079","DOI":"10.1016\/j.jacc.2018.05.079"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5) Hsu CY, Hogan EL, Wingfield W Jr, et al. Orthostatic hypotension with brainstem tumors. Neurology. 1984;34 (9):1137-43. doi: 10.1212\/wnl.34.9.1137","DOI":"10.1212\/WNL.34.9.1137"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6) Hocker S, Hoover JM, Puffer RC, et al. Orthostatic hypotension following resection of a dorsal medullary hemangioblastoma. Neurocrit Care. 2012;16 (2):306-10. doi: 10.1007\/s12028-011-9656-y","DOI":"10.1007\/s12028-011-9656-y"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7) Jabary NS, Sarabia R, Sanchez T, et al. Midodrine treatment in the management of severe orthostatic hypotension after hemangioblastoma surgery. Acta Neurochir (Wien). 2007;149 (3):303-5. doi: 10.1007\/s00701-006-1103-z","DOI":"10.1007\/s00701-006-1103-z"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8) Nangunoori R, Koduri S, Singh A, et al. Refractory orthostatic hypotension caused by a recurrent hemangioblastoma: case report and review of the literature. Cureus. 2016;8 (3):e540. doi: 10.7759\/cureus.540","DOI":"10.7759\/cureus.540"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9) Jacobsen KS, Schou RF, Poulsen FR, et al. Orthostatic hypotension after cervicomedullary junction surgery: illustrative case. J Neurosurg Case Lessons. 2021;2 (20):CASE21448. doi: 10.3171\/CASE21448","DOI":"10.3171\/CASE21448"},{"key":"10","doi-asserted-by":"publisher","unstructured":"10) Idiaquez J, Araya P, Benarroch E. Orthostatic hypotension associated with dorsal medullary cavernous angioma. Acta Neurol Scand. 2009;119 (1):45-8. doi: 10.1111\/j.1600-0404.2008.01050.x","DOI":"10.1111\/j.1600-0404.2008.01050.x"},{"key":"11","doi-asserted-by":"publisher","unstructured":"11) Tadros R, Tonkin A. Bilateral bulbar palsy and postural hypotension following surgery for fourth ventricle subependymoma. J Clin Neurosci. 2009;16 (12):1646-8. doi: 10.1016\/j.jocn.2009.02.017","DOI":"10.1016\/j.jocn.2009.02.017"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12) Mart\u00edn-Gallego A, Andrade-Andrade I, Dawid-Milner MS, et al. Autonomic dysfunction elicited by a medulla oblongata injury after fourth ventricle tumor surgery in a pediatric patient. Auton Neurosci. 2016;194:52-7. doi: 10.1016\/j.autneu.2015.12.002","DOI":"10.1016\/j.autneu.2015.12.002"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13) Nagumo M, Tashiro S, Hijikata N, et al. Conservative rehabilitation for a patient presenting with severe orthostatic hypotension after surgical management of brainstem tumor: illustrative case. J Neurosurg Case Lessons. 2021;1 (25):CASE2136. doi: 10.3171\/CASE2136","DOI":"10.3171\/CASE2136"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14) G\u00f3mez-Esteban JC, Berganzo K, Tijero B, et al. Orthostatic hypotension associated with an epidermoid tumor of the IV ventricle. J Neurol. 2009;256 (8):1357-9. doi: 10.1007\/s00415-009-5102-x","DOI":"10.1007\/s00415-009-5102-x"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15) Telerman-Toppet N, Vanderhaeghen JJ, Warszawski M. Orthostatic hypotension with lower brain stem glioma. J Neurol Neurosurg Psychiatry. 1982;45 (12):1147-50. doi: 10.1136\/jnnp.45.12.1147","DOI":"10.1136\/jnnp.45.12.1147"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Wang Y, Pan C, Xie M, et al. Adult diffuse intrinsic pontine glioma: clinical, radiological, pathological, molecular features, and treatments of 96 patients. J Neurosurg. 2022;137 (6):1628-38. doi: 10.3171\/2022.2.JNS211920","DOI":"10.3171\/2022.2.JNS211920"}],"container-title":["NMC Case Report Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/nmccrj\/13\/0\/13_2025-0286\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T04:37:58Z","timestamp":1771043878000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/nmccrj\/13\/0\/13_2025-0286\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12,31]]},"references-count":16,"journal-issue":{"issue":"0","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.2176\/jns-nmc.2025-0286","relation":{},"ISSN":["2188-4226"],"issn-type":[{"value":"2188-4226","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,12,31]]},"article-number":"2025-0286"}}