{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:20:34Z","timestamp":1783776034622,"version":"3.55.0"},"reference-count":20,"publisher":"Japan Neurosurgical Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurol. Med. Chir.(Tokyo)"],"published-print":{"date-parts":[[2012]]},"DOI":"10.2176\/nmc.52.318","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T19:13:16Z","timestamp":1424718796000},"page":"318-326","source":"Crossref","is-referenced-by-count":28,"title":["Diagnostic Imaging of Higher Brain Dysfunction in Patients With Adult Moyamoya Disease Using Statistical Imaging Analysis for [<sup>123<\/sup>I]Iomazenil Single Photon Emission Computed Tomography"],"prefix":"10.2176","volume":"52","author":[{"given":"Jyoji","family":"NAKAGAWARA","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"OSATO","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"KAMIYAMA","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"HONJO","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironori","family":"SUGIO","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentarou","family":"FUMOTO","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"MURAHASHI","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"TAKADA","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiichi","family":"WATANABE","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohiko","family":"NAKAMURA","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Stroke Center, Nakamura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"971","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Baird A, Dewar BK, Critchley H, Gilbert SJ, Dolan RJ, Cipolotti L: Cognitive functioning after medial frontal lobe damage including the anterior cingulate cortex: A preliminary investigation. Brain Cogn<\/i> 60: 166-175, 2006","DOI":"10.1016\/j.bandc.2005.11.003"},{"key":"2","unstructured":"2) Beer HF, Blauenstein PA, Hasler PH, Delaloye B, Riccabona G, Bangerl I, Hunkeler W, Bonetti EP, Pieri L, Richards JG, Schubiger PA: In vitro and in vivo evaluation of iodine-123 Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors. J Nucl Med<\/i> 31: 1007-1014, 1990"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) DeGirolami U, Crowell RM, Marcoux FW: Selective necrosis and total necrosis in focal cerebral ischemia: neuropathologic observations on experimental middle cerebral artery occlusion in the macaque monkey. J Neuropathol Exp Neurol<\/i> 43: 57-71, 1984","DOI":"10.1097\/00005072-198401000-00005"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Garcia JH, Lassen NA, Weiller C, Sperling B, Nakagawara J: Ischemic stroke and incomplete infarction. Stroke<\/i> 27: 761-765, 1996","DOI":"10.1161\/01.STR.27.4.761"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Garcia JH, Liu KF, Ho KL: Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex. Stroke<\/i> 26: 636-643, 1995","DOI":"10.1161\/01.STR.26.4.636"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Garcia JH, Wagner S, Liu KF, Hu XJ: Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats: statistical validation. Stroke<\/i> 26: 627-635, 1995","DOI":"10.1161\/01.STR.26.4.627"},{"key":"7","unstructured":"7) Hatazawa J, Satoh T, Shimosegawa E, Okudera T, Inugami A, Ogawa T, Fujita H, Noguchi K, Kanno I, Miura S, Murakami M, lida H, Miura Y, Uemura K: Evaluation of cerebral infarction with iodine-123-iomazenil SPECT. J Nucl Med<\/i> 36: 2154-2161, 1995"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Karzmark P, Zeifert P, Bell-Stephens TE, Steinberg GK, Dorfman LJ: Neurocognitive impairment in adults with moyamoya disease without stroke. Neurosurgery<\/i> 70: 634-638, 2012","DOI":"10.1227\/NEU.0b013e3182320d1a"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Kim KM, Watabe H, Hayashi T, Hayashida K, Katafuchi T, Enomoto N, Ogura T, Shidahara M, Takikawa S, Eberl S, Nakazawa M, Iida H: Quantitative mapping of basal and vasareactive cerebral blood flow using split-dose 123<\/sup>I-iodoamphetamine and single photon emission computed tomography. Neuroimage<\/i> 33: 1126-1135, 2006","DOI":"10.1016\/j.neuroimage.2006.06.064"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Lassen NA: Neuroreceptor quantitation in vivo by the steady-state principle using constant infusion or bolus injection of radioactive tracers. J Cereb Blood Flow Metab<\/i> 12: 709-716, 1992","DOI":"10.1038\/jcbfm.1992.101"},{"key":"11","unstructured":"11) Minoshima S, Frey KA, Koeppe RA, Foster NL, Kuhl DE: A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET. J Nucl Med<\/i> 36: 1238-1248, 1995"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Mizumura S, Kumita S, Cho K, Ishihara M, Nakajo H, Toba M, Kumazaki T: Development of quantitative analysis method for stereotactic brain image: Assessment of reduced accumulation in extent and severity using anatomical segmentation. Ann Nucl Med<\/i> 17: 289-295, 2003","DOI":"10.1007\/BF02988523"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Mizumura S, Nakagawara J, Takahashi M, Kumita S, Cho K, Nakajo H, Toba M, Kumazaki T: Three-dimensional display in staging hemodynamic brain ischemia for JET study: Objective evaluation using SEE analysis and 3D-SSP display. Ann Nucl Med<\/i> 18: 13-21, 2004","DOI":"10.1007\/BF02985609"},{"key":"14","unstructured":"14) Nakagawara J: [Assessment of brain functions by neuron maker on SPECT imaging]. No Junkan Taisha<\/i> 18: 149-154, 2006 (Japanese)"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Nakagawara J: Iomazenil SPECT (BZR-receptor), in<\/i> Cho BK, Tominaga T (eds<\/i>): Moyamoya Disease Update<\/i>. Tokyo, Springer, 2010, pp 189-196","DOI":"10.1007\/978-4-431-99703-0_27"},{"key":"16","unstructured":"16) Nakagawara J, Kamiyama K, Takahashi M, Nakamura H: [Neuroimaging of post-traumatic higher brain dysfunction using 123<\/sup>I-Iomazenil (IMZ) SPECT]. Shinkei Gaisho<\/i> 33: 165-172, 2010 (Japanese)"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Nakagawara J, Sperling B, Lassen NA: Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil. Stroke<\/i> 28: 124-132, 1997","DOI":"10.1161\/01.STR.28.1.124"},{"key":"18","unstructured":"18) Nakajima Y, Terashima A: [Handbook of Higher Brain Dysfunction<\/i>]. Tokyo, Igaku Shoin, 2006 (Japanese)"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Rudebeck PH, Bannerman DM, Rushworth MF: The contribution of distinct subregions of the ventromedial frontal cortex to emotion, social behavior, and decision making. Cogn Affect Behav Neurosci<\/i> 8: 485-497, 2008","DOI":"10.3758\/CABN.8.4.485"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Sette G, Baron JC, Young AR, Miyazawa H, Tillet I, Barré L, Travère JM, Derlon JM, MacKenzie ET: In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon. Stroke<\/i> 24: 2046-2057, 1993","DOI":"10.1161\/01.STR.24.12.2046"}],"container-title":["Neurologia medico-chirurgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/nmc\/52\/5\/52_2012-0015\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T02:06:23Z","timestamp":1498183583000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/nmc\/52\/5\/52_2012-0015\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2176\/nmc.52.318","relation":{},"ISSN":["0470-8105","1349-8029"],"issn-type":[{"value":"0470-8105","type":"print"},{"value":"1349-8029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}