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Transl Res<\/i>. 148<\/b>: 281-288, 2006."},{"key":"2","unstructured":"2) Li, Y., et al.: A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sj\u00f6gren's syndrome at 7q11.23. Nat Genet<\/i>. 45<\/b>: 1361-1365, 2013."},{"key":"3","unstructured":"3) Sarigul, M., et al.: The numbers of Foxp3+ Treg cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sj\u00f6gren's syndrome. Lupus<\/i>. 19<\/b>: 138-145, 2010."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Lin, X., et al.: Th17 cells play a critical role in the development of experimental Sjogren's syndrome. Ann Rheum Dis<\/i>. 2014. Epub ahead of print.","DOI":"10.1136\/annrheumdis-2013-204584"},{"key":"5","unstructured":"5) Inoue, H., et al.: Possible involvement of EBV-mediated alpha-fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome. J Immunol<\/i>. 166<\/b>: 5801-5809, 2001."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Lucchesi, D., et al.: EBV and other viruses as triggers of tertiary lymphoid structures in primary Sj\u00f6gren's syndrome. Expert Rev Clin Immunol<\/i>. 2014. Epub ahead of print.","DOI":"10.1586\/1744666X.2014.892417"},{"key":"7","unstructured":"7) Fleck, M., et al.: Murine cytomegalovirus induces a Sj\u00f6gren's syndrome-like disease in C57Bl\/6-lpr\/lpr mice. Arthritis Rheum<\/i>. 41<\/b>: 2175-2184, 1998."},{"key":"8","unstructured":"8) Garc\u00eda-Carrasco, M., et al.: Hepatitis C virus infection in \u2018primary\u2019 Sj\u00f6gren's syndrome: prevalence and clinical significance in a series of 90 patients. Ann Rheum Dis<\/i>. 56<\/b>: 173-175, 1997."},{"key":"9","unstructured":"9) Nakamura, H., et al.: Apoptosis in labial salivary glands from Sj\u00f6gren's syndrome (SS) patients: comparison with human T lymphotropic virus-I (HTLV-I)-seronegative and -seropositive SS patients. Clin Exp Immunol<\/i>. 114<\/b>: 106-112, 1998."},{"key":"10","unstructured":"10) Ohlsson, M., et al.: Fas-induced apoptosis is a rare event in Sj\u00f6gren's syndrome. Lab Invest<\/i>. 81<\/b>: 95-105, 2001."},{"key":"11","unstructured":"11) Nakamura, H., et al.: Detection of soluble form of Fas ligand (sFasL) and sFas in the saliva from patients with Sj\u00f6gren's syndrome: Positive correlation between sFas ligand concentration in the saliva and radiographic salivary gland destruction. Clin Exp Rheumatol<\/i>. 23<\/b>: 915, 2005."},{"key":"12","unstructured":"12) Kayagaki, N., et al.: Metalloproteinase-mediated release of human Fas ligand. J Exp Med<\/i>. 182<\/b>: 1777-1783, 1995."},{"key":"13","unstructured":"13) P\u00e9rez, P., et al.: Increased acinar damage of salivary glands of patients with Sj\u00f6gren's syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3\/tissue inhibitor of metalloproteinases 1 and matrix metalloproteinase 9\/tissue inhibitor of metalloproteinases 1 ratios. Arthritis Rheum<\/i>. 52<\/b>: 2751-2760, 2005."},{"key":"14","unstructured":"14) Asatsuma, M., et al.: Increase in the ratio of matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 in saliva from patients with primary Sj\u00f6gren's syndrome. Clin Chim Acta<\/i>. 345<\/b>: 99-104, 2004."},{"key":"15","unstructured":"15) Tsubata, T., et al.: B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature<\/i>. 364<\/b>: 645-648, 1993."},{"key":"16","unstructured":"16) Nakamura, H., et al.: Expression of CD40\/CD40 ligand and Bcl-2 family proteins in labial salivary glands of patients with Sj\u00f6gren's syndrome. Lab Invest<\/i>. 79<\/b>: 261-269, 1999."},{"key":"17","unstructured":"17) Nakamura, H., et al.: Expression of mitogen activated protein kinases in labial salivary glands of patients with Sj\u00f6gren's syndrome. Ann Rheum Dis<\/i>. 58<\/b>: 382-385, 1999."},{"key":"18","unstructured":"18) Soejima, K., et al.: Activation of MKK4 (SEK1), JNK, and c-Jun in labial salivary infiltrating T cells in patients with Sj\u00f6gren's syndrome. Rheumatol Int<\/i>. 27<\/b>: 329-333, 2007."},{"key":"19","unstructured":"19) Nakamura, H., et al.: Epidermal growth factor inhibits Fas-mediated apoptosis in salivary epithelial cells of patients with primary Sj\u00f6gren's syndrome. Clin Exp Rheumatol<\/i>. 25<\/b>: 831-837, 2007."},{"key":"20","unstructured":"20) Nakamura, H., et al.: EGF activates PI3K-Akt and NF-kB via distinct pathways in salivary epithelial cells in Sj\u00f6gren's syndrome. Rheumatol Int<\/i>. 28<\/b>: 127-136, 2007."},{"key":"21","unstructured":"21) Nakamura, H., et al.: Rapid and significant induction of TRAIL-mediated type II cells in apoptosis of primary salivary epithelial cells in primary Sj\u00f6gren's syndrome. Apoptosis<\/i>. 13<\/b>: 1322-1330, 2008."},{"key":"22","unstructured":"22) Kawakami, A., et al.: Toll-like receptor in salivary glands from patients with Sj\u00f6gren's syndrome: functional analysis by human salivary gland cell line. J Rheumatol<\/i>. 34<\/b>: 1019-1026, 2007."},{"key":"23","unstructured":"23) Nakamura, H., et al.: TLR3-mediated apoptosis and activation of phosphorylated Akt in the salivary gland epithelial cells of primary Sj\u00f6gren's syndrome patients. Rheumatol Int<\/i>. 33<\/b>: 441-450, 2013."},{"key":"24","unstructured":"24) Khvalevsky, E., et al.: TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. J Cell Biochem<\/i>. 100<\/b>: 1301-1312, 2007."},{"key":"25","unstructured":"25) Green, J.E., et al.: Exocrinopathy resembling Sj\u00f6gren's syndrome in HTLV-1 tax transgenic mice. Nature<\/i>. 341<\/b>: 72-74, 1989."},{"key":"26","unstructured":"26) Yamada, S., et al.: Cytokine-producing mammary carcinomas in transgenic rats carrying the pX gene of human T-lymphotropic virus type I. Cancer Res<\/i>. 55<\/b>: 2524-2527, 1995."},{"key":"27","unstructured":"27) Eguchi, K., et al.: Primary Sj\u00f6gren's syndrome with antibodies to HTLV-I: clinical and laboratory features. Ann Rheum Dis<\/i>. 51<\/b>: 769-776, 1992."},{"key":"28","unstructured":"28) Terada, K., et al.: Prevalence of serum and salivary antibodies to HTLV-1 in Sj\u00f6gren's syndrome. Lancet<\/i>. 344<\/b>: 1116-1119, 1994."},{"key":"29","unstructured":"29) Hida, A., et al.: Association of human T lymphotropic virus type I with Sj\u00f6gren syndrome. Ann Rheum Dis<\/i>. 69<\/b>: 2056-2057, 2010."},{"key":"30","unstructured":"30) Nakamura, H., et al.: High prevalence of Sj\u00f6gren's syndrome in patients with HTLV-I associated myelopathy. Ann Rheum Dis<\/i>. 56<\/b>: 167-172, 1997."},{"key":"31","unstructured":"31) Nakamura, H., et al.: Expression and function of X chromosome-linked inhibitor of apoptosis protein in Sj\u00f6gren's syndrome. Lab Invest<\/i>. 80<\/b>: 1421-1427, 2000."},{"key":"32","unstructured":"32) Nakamura, H., et al.: HTLV-I infection results in resistance toward salivary gland destruction of Sj\u00f6gren's syndrome. Clin Exp Rheumatol<\/i>. 26<\/b>: 653-655, 2008."},{"key":"33","unstructured":"33) Amft, N., et al.: Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sj\u00f6gren's syndrome. Arthritis Rheum<\/i>. 44<\/b>: 2633-2641, 2001."},{"key":"34","unstructured":"34) Nakamura, H., et al.: Low prevalence of ectopic germinal centre formation in patients with HTLV-I-associated Sj\u00f6gren's syndrome. Rheumatology<\/i> (Oxford<\/i>). 48<\/b>: 854-855, 2009."},{"key":"35","unstructured":"35) Nakamura, H., et al.: HTLV-I virological and histopathological analysis in two cases of anti-centromere-antibody-seropositive Sj\u00f6gren's syndrome. Mod Rheumatol<\/i>. 23<\/b>: 133-139, 2013."},{"key":"36","unstructured":"36) Nakamura, H., et al.: A case of adult T-cell leukemia presenting primary Sj\u00f6gren's syndrome like symptoms. 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