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J., et al.: The link between periodontal disease and rheumatoid arthritis: an updated review. <i>Curr Rheumatol Rep<\/i>. <b>16<\/b>: 408, 2014."},{"key":"6","unstructured":"6) Li, P., et al.: PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. <i>J Exp Med<\/i>. <b>207<\/b>: 1853-1862, 2010."},{"key":"7","unstructured":"7) Klareskog, L., et al.: Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis. <i>Semini Immunol<\/i>. <b>23<\/b>: 92-98, 2011."},{"key":"8","unstructured":"8) Reynisdottir, G., et al.: Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis. <i>Ann Rheum Dis<\/i>. <b>75<\/b>: 1722-1727, 2016."},{"key":"9","unstructured":"9) James, E.A., et al.: HLA\u2013DR1001 presents \u201caltered-self\u201d peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets. <i>Arthritis Rheum<\/i>. <b>62<\/b>: 2909-2918, 2010."},{"key":"10","unstructured":"10) van der Woude, D., et al.: Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis. <i>Ann Rheum Dis<\/i>. <b>69<\/b>: 1554-1561, 2010."},{"key":"11","unstructured":"11) Suwannalai, P., et al.: Avidity maturation of anti\u2013citrullinated protein antibodies in rheumatoid arthritis. <i>Arthritis Rheum<\/i>. <b>64<\/b>: 1323-1328, 2012."},{"key":"12","unstructured":"12) Lu, M.C., et al.: Anti\u2013citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte\/macrophages and stimulate tumor necrosis factor production. <i>Arthritis Rheum<\/i>. <b>62<\/b>: 1213-1223, 2010."},{"key":"13","unstructured":"13) Lu, M.C., et al.: Anti-citrullinated protein antibodies activated ERK1\/2 and JNK mitogen-activated protein kinases via binding to surface-expressed citrullinated GRP78 on mononuclear cells. <i>J Clin Immunol<\/i>. <b>33<\/b>: 558-566, 2013."},{"key":"14","unstructured":"14) Clavel, C., et al.: Induction of macrophage secretion of tumor necrosis factor through Fc receptor IIa engagement by rheumatoid arthritis\u2013specific autoantibodies to citrullinated proteins complexed with fibrinogen. <i>Arthritis Rheum<\/i>. <b>58<\/b>: 678-688, 2008."},{"key":"15","unstructured":"15) Laurent, L., et al.: Fc\u03b3 receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins. <i>Ann Rheum Dis<\/i>. <b>70<\/b>: 1052-1059, 2011."},{"key":"16","unstructured":"16) Snir, O., et al.: Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. <i>Arthritis Rheum<\/i>. <b>62<\/b>: 44-52, 2010."},{"key":"17","unstructured":"17) Kinloch, A., et al.: Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis. <i>Arthritis Res Ther<\/i>. <b>7<\/b>: R1421-1429, 2005."},{"key":"18","unstructured":"18) Foulquier, C., et al.: Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. <i>Arthritis Rheum<\/i>. <b>56<\/b>: 3541-3553, 2007."},{"key":"19","unstructured":"19) Umeda, N., et al.: Anti-cyclic citrullinated glucose-6-phosphate isomerase peptide-7 (CCG-7) antibodies were suppressed by biologics treatment and deposited to citrullinated proteins in CD68-positive cells in the RA synovium. <i>Mod Rheumatol<\/i>. <b>27<\/b>: 194-196, 2017."},{"key":"20","unstructured":"20) Harre, U., et al.: Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. <i>J Clin Invest<\/i>. <b>122<\/b>: 1791-1802, 2012."},{"key":"21","unstructured":"21) Trouw, L.A., et al.: Autoimmunity in rheumatoid arthritis: 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