{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T22:15:55Z","timestamp":1774044955734,"version":"3.50.1"},"reference-count":51,"publisher":"Japan Academy","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Proc. Jpn. Acad., Ser. B","Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences"],"published-print":{"date-parts":[[2010]]},"DOI":"10.2183\/pjab.86.229","type":"journal-article","created":{"date-parts":[[2010,3,15]],"date-time":"2010-03-15T06:03:38Z","timestamp":1268633018000},"page":"229-243","source":"Crossref","is-referenced-by-count":24,"title":["A new paradigm of bacteria-gut interplay brought through the study of <bold>Shigella<\/bold>"],"prefix":"10.2183","volume":"86","author":[{"given":"Chihiro","family":"SASAKAWA","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"993","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1814"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Ashida, H., Ogawa, M., Mimuro, H. and Sasakawa, C. (2009) Shigella<\/i> infection of intestinal epithelium and circumvention of the host innate defense system. Curr. Top. Microbiol. Immunol. 337<\/b>, 231–255.","DOI":"10.1007\/978-3-642-01846-6_8"},{"key":"3","unstructured":"3) Shiga, K. (1898) Ueber den errenger der dysenterie in Japan. Zent. Bakteriol. Microbiol. Hyg. 23<\/b>, 599–600."},{"key":"4","unstructured":"4) Trofa, A.F., Ueno-Olsen, H., Oiwa, R. and Yoshikawa, M. (1999) Dr. Kiyoshi Shiga: discovery of the dysentery bacillus. Clin. Infect. Dis. 29<\/b>, 1303–1306."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) DuPont, H.L., Levine, M.M., Hornick, R.B. and Formal, S.B. (1989) Inoculum size in shigellosis and implications for expected mode of transmission. J. Infect. Dis. 159<\/b>, 1126–1128.","DOI":"10.1093\/infdis\/159.6.1126"},{"key":"6","unstructured":"6) Keusch, G.T. (2001) Shigella. Mol. Med. Microbiol. (ed. Sussman, M.) 2<\/b>, Academic Press, London, pp. 1279–1290."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Sasakawa, C. (2004) Shigella<\/i> invasion. Adv. Mol. Cell. Microbiol. (ed. Lamont, R.J.). Cambridge University Press, Cambridge, U.K., pp. 25–58.","DOI":"10.1017\/CBO9780511546273.004"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2007.02.004"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M414671200"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Suzuki, T., Franchi, L., Toma, C., Ashida, H., Ogawa, M., Yoshikawa, Y. et al<\/i>. (2007) Differential regulation of caspase-1 activation, pyroptosis and autophagy via Ipaf and ASC in Shigella<\/i>-infected macrophages. PLos. Pathog. 3<\/b>, e111.","DOI":"10.1371\/journal.ppat.0030111"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2070"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Kufer, T.A., Kremmer, E., Adam, A.C., Philpott, D.J. and Sansonetti, P.J. (2007) The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell. Microbiol. 10<\/b>, 477–486.","DOI":"10.1111\/j.1462-5822.2007.01062.x"},{"key":"13","unstructured":"13) Tattoli, I., Carneiro, L.A., Jéhanno, M., Magalhaes, J.G., Shu, Y., Philpott, D.J. et al.<\/i> (2008) NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production. EMBO Rep. 9<\/b>, 293–300."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Carneiro, L.A., Travassos, L.H., Soares, F., Tattoli, I., Magalhaes, J.G., Bozza, M.T. et al<\/i>. (2009) Shigella<\/i> induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell. Host. Microbe. 5<\/b>, 123–136.","DOI":"10.1016\/j.chom.2008.12.011"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M502509200"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1526"},{"key":"17","unstructured":"17) Huang, Z., Sutton, S.E., Wallenfang, A.J., Orchard, R.C., Wu, X., Feng, Y. et al.<\/i> (2009) Structure insights into host GTPase isoform selection by a family of bacterial GEF mimics. Nat. Strct. Mol. Biol. 16<\/b>, 853–860."},{"key":"18","unstructured":"18) Ogawa, H., Nakamura, A. and Nakaya, R. (1968) Cinemicroscopic study of tissue cell cultures infected with Shigella flexneri<\/i>. Jpn. J. Med. Sci. Biol. 21<\/b>, 259–273."},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(86)90880-9"},{"issue":"1","key":"20","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1128\/jb.171.1.353-359.1989","volume":"171","year":"1989","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9193","issn-type":"print"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.10.3867"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Cossart, P. and Sansonetti, P.J. (2004) Bacterial invasion: the paradigms of enteroinvasive pathogens. Science 303<\/b>, 242–248.","DOI":"10.1126\/science.1090124"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2004.12.013"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.10.2767"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1084\/jem.191.11.1905"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Leung, Y., Ally, S. and Goldberg, M.B. (2008) Bacterial actin assembly requires Toca-1 to relieve N-WASP autoinhibition. Cell Host Microbe 3<\/b>, 39–47.","DOI":"10.1016\/j.chom.2007.10.011"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdf319"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1126\/science.1133174"},{"issue":"3","key":"29","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/j.1365-2958.2006.05547.x","volume":"63","author":"ASHIDA HIROSHI","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/0950-382X","issn-type":"print"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2006"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Rohde, J.R., Breitkreutz, A., Chenal, A., Sansonetti, P.J. and Parsot, C. (2007) Type III secretion effectors of the IpaH family are E3 ubiquitin ligase. Cell Host Microbe 1<\/b>, 77–83.","DOI":"10.1016\/j.chom.2007.02.002"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Deretic, V. and Levine, B. (2009) Autophagy, immunity, and microbial adaptations. Cell Host Microbe 18<\/b>, 527–549.","DOI":"10.1016\/j.chom.2009.05.016"},{"key":"33","unstructured":"33) Ogawa, M. and Sasakawa, C. (2006) Shigella<\/i> and autophagy. Autophagy 2<\/b>, 171–174."},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1126\/science.1106036"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03489.x"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Dupont, N., Lacas-Gervais, S., Bertout, J., Paz, I., Freche, B., Tran, V. et al.<\/i> (2009) Shigella<\/i> phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe 6<\/b>, 137–149.","DOI":"10.1016\/j.chom.2009.07.005"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1967"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1126\/science.1104815"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.043"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Mimuro, H., Suzuki, T., Nagai, S., Rieder, G., Suzuki, M., Fujita, Y. et al.<\/i> (2007) Helicobacter pylori<\/i> dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe 11<\/b>, 250–263.","DOI":"10.1016\/j.chom.2007.09.005"},{"key":"41","unstructured":"41) Nougayrède, J.P., Taieb, F., De Rycke, J. and Oswald, E. (2005) Cyclomodulins: bacterial effectors that modulate the eukaryotic cell cycle. Trends Microbiol. 13<\/b>, 103–110."},{"key":"42","doi-asserted-by":"crossref","unstructured":"42) Tanaka, J., Suzuki, T., Mimuro, H. and Sasakawa, C. (2003) Structural definition on the surface of Helicobacter pylori<\/i> type IV secretion apparatus. Cell Microbiol. 5<\/b>, 395–404.","DOI":"10.1046\/j.1462-5822.2003.00286.x"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1038\/nature07952"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1789"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.017996"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.16.8829"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200412151"},{"key":"48","unstructured":"48) Kotloff, K.L., Winickoff, J.P., Ivanoff, B., Clemens, J.D., Swerdlow, D.L., Sansonetti, P.J. et al.<\/i> (1999) Global burden of Shigella<\/i> infections: implications for vaccine development and implementation of control strategies. Bulletin of the World Health Organization 77<\/b>, 651–666."},{"key":"49","doi-asserted-by":"crossref","unstructured":"49) Yoshikawa, M., Sasakawa, C., Okada, N., Takasaka, N., Nakayama, M., Yoshikawa, Y. et al.<\/i> (1995) Construction and evaluation of a virG thyA<\/i> double mutant of Shigella flexneri<\/i> 2a as a candidate live-attenuated oral vaccine. Vaccine 13<\/b>, 1436–1440.","DOI":"10.1016\/0264-410X(95)00071-8"},{"key":"50","unstructured":"50) Suzuki, T., Yoshikawa, Y., Ashida, H., Iwai, H., Toyotome, T., Matsui, H. and Sasakawa, C. (2006) High vaccine efficacy against shigellosis of recombinanat noninvasive Shigella<\/i> mutant that express Yersinia<\/i> invasin. J. Immunol. 177<\/b>, 4709–4717."},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Shim, D.H., Suzuki, T., Chang, S.Y., Park, S.M., Sansonetti, P.J., Sasakawa, C. and Kweon, M.N. (2007) New animal model of shigellosis in the guinea pig: its usefulness for protective efficacy studies. J. Immunol. 178<\/b>, 2476–2482.","DOI":"10.4049\/jimmunol.178.4.2476"}],"container-title":["Proceedings of the Japan Academy, Series B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/pjab\/86\/3\/86_3_229\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T03:00:57Z","timestamp":1711335657000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/pjab\/86\/3\/86_3_229\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.2183\/pjab.86.229","relation":{},"ISSN":["0386-2208","1349-2896"],"issn-type":[{"value":"0386-2208","type":"print"},{"value":"1349-2896","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}