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Chemistry 21, 2621\u20132628.","DOI":"10.1002\/chem.201405629"},{"key":"10","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1055\/s-2004-817767","author":"M. Inoue","year":"2004","unstructured":"10) Inoue, M. and Hirama, M. (2004) Total synthesis of ciguatoxin CTX3C, a causative toxin of ciguatera seafood poisoning. Synlett, 577\u2013595.","journal-title":"Synlett","ISSN":"https:\/\/id.crossref.org\/issn\/0936-5214","issn-type":"print"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Inoue, M. and Hirama, M. (2004) Evolution of a practical total synthesis of ciguatoxin CTX3C. Acc. Chem. Res. 37, 961\u2013968.","DOI":"10.1021\/ar0301577"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Hirama, M. (2005) Total synthesis of ciguatoxin CTX3C: a venture into the problems of ciguatera seafood poisoning. Chem. 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(1999) Synthetic study of C-1027 chromophore: enantioselective synthesis of \u03b2-tyrosine moiety and effective aryl ether formation. Chem. Lett., 511\u2013512.","DOI":"10.1246\/cl.1999.511"},{"key":"144","doi-asserted-by":"crossref","unstructured":"144) Sato, I., Akahori, Y., Sasaki, T., Kikuchi, T. and Hirama, M. (1999) Synthetic study of C-1027 chromophore. Highly stereoselective glycosylation. Chem. Lett., 867\u2013868.","DOI":"10.1246\/cl.1999.867"},{"key":"145","doi-asserted-by":"crossref","unstructured":"145) Wang, G.X., Iguchi, S. and Hirama, M. (2001) A very concise and stereoselective synthesis of 3-substituted cis-hex-3-ene-1,5-diyne and corresponding epoxydiyne. J. Org. Chem. 66, 2146\u20132148.","DOI":"10.1021\/jo0016125"},{"key":"146","doi-asserted-by":"crossref","unstructured":"146) Sasaki, T., Inoue, M. and Hirama, M. (2001) Synthetic studies toward C-1027 chromophore: construction of a highly unsaturated macrocycle. Tetrahedron Lett. 42, 5299\u20135303.","DOI":"10.1016\/S0040-4039(01)00959-5"},{"key":"147","doi-asserted-by":"crossref","unstructured":"147) Inoue, M., Kikuchi, T. and Hirama, M. (2004) Synthesis of the fully functionalized nine-membered diyne core of the C-1027 chromophore. Tetrahedron Lett. 45, 6439\u20136442.","DOI":"10.1016\/j.tetlet.2004.06.136"},{"key":"148","doi-asserted-by":"crossref","unstructured":"148) Inoue, M., Hatano, S., Kodama, M., Sasaki, T., Kikuchi, T. and Hirama, M. (2004) Synthesis of the bicyclo[7.3.0]dodecatrienediyne core of the C-1027 chromophore. Org. Lett. 6, 3833\u20133836.","DOI":"10.1021\/ol048494i"},{"key":"149","unstructured":"149) Hirai, K., Tamura, Y., Sato, I. and Hirama, M. (2010) Practical synthesis of the C-1027 aminosugar moiety. Synlett, 2156\u20132158."},{"key":"150","doi-asserted-by":"crossref","unstructured":"150) Kawata, S., Ashizawa, S. and Hirama, M. (1997) Synthetic study of kedarcidin chromophore: revised structure. J. Am. Chem. 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Tetrahedron Lett. 40, 8281\u20138285.","DOI":"10.1016\/S0040-4039(99)01744-X"},{"key":"154","doi-asserted-by":"crossref","unstructured":"154) Koyama, Y., Lear, M.J., Yoshimura, F., Ohashi, I., Mashimo, T. and Hirama, M. (2005) Efficient construction of the kedarcidin chromophore ansamacrolide. Org. Lett. 7, 267\u2013270.","DOI":"10.1021\/ol0477374"},{"key":"155","doi-asserted-by":"crossref","unstructured":"155) Yoshimura, F., Lear, M.J., Ohashi, I., Koyama, Y. and Hirama, M. (2007) Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon. Chem. Commun., 3057\u20133059.","DOI":"10.1039\/b705932a"},{"key":"156","doi-asserted-by":"crossref","unstructured":"156) Ogawa, K., Koyama, Y., Ohashi, I., Sato, I. and Hirama, M. (2008) Secure route to the epoxybicyclo[7.3.0]dodecadienediyne core of the kedarcidin chromophore. Chem. Commun., 6327\u20136329.","DOI":"10.1039\/b814595d"},{"key":"157","doi-asserted-by":"crossref","unstructured":"157) Lear, M.J. and Hirama, M. 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(1981) The absolute stereochemistry and conformation of avermectin B<sub>2a<\/sub> aglycon and avermectin B<sub>1a<\/sub>. J. Am. Chem. Soc. 103, 4221\u20134224.","DOI":"10.1021\/ja00404a041"},{"key":"169","doi-asserted-by":"publisher","unstructured":"169) \u014cmura, S. (2011) Microbial metabolites: 45 years of wandering, wondering and discovering. Tetrahedron 67, 6420\u20136459.","DOI":"10.1016\/j.tet.2011.03.117"},{"key":"170","doi-asserted-by":"crossref","unstructured":"170) Mishima, H., Ide, J., Muramatsu, S. and Ono, M. (1983) Milbemycins, a new family of macrolide antibiotics. Structure determination of milbemycins D, E, F, G, H, J and K. J. Antibiot. 36, 980\u2013990.","DOI":"10.7164\/antibiotics.36.980"},{"key":"171","doi-asserted-by":"crossref","unstructured":"171) Hanessian, S., Ugolini, A., Dube, D., Hodges, P.J. and Andre, C. (1986) Synthesis of (+)-avermectin B<sub>1a<\/sub>. J. Am. Chem. Soc. 108, 2776\u20132778.","DOI":"10.1021\/ja00270a059"},{"key":"172","doi-asserted-by":"crossref","unstructured":"172) Fraser-Reid, B., Wolleb, H., Faghih, R. and Barchi, J. Jr. (1987) Avermectin chemistry: problems of conjugation, deconjugation, and epimerization. J. Am. Chem. Soc. 109, 933\u2013935.","DOI":"10.1021\/ja00237a068"},{"key":"173","doi-asserted-by":"crossref","unstructured":"173) Hanessian, S., Dube, D. and Hodges, P.J. (1987) Studies on the deconjugation-epimerization strategy en route to avermectin B<sub>1a<\/sub>: problems and solutions. J. Am. Chem. Soc. 109, 7063\u20137067.","DOI":"10.1021\/ja00257a026"},{"key":"174","doi-asserted-by":"crossref","unstructured":"174) Danishefsky, S.J., Armistead, D.M., Wincott, F.E., Selnick, H.G. and Hungate, R. (1987) The total synthesis of avermectin A<sub>1a<\/sub>. The total synthesis of the aglycon of avermectin A<sub>1a<\/sub>. J. Am. Chem. Soc. 109, 8117\u20138119.","DOI":"10.1021\/ja00260a045"},{"key":"175","doi-asserted-by":"crossref","unstructured":"175) Danishefsky, S.J., Armistead, D.M., Wincott, F.E., Selnick, H.G. and Hungate, R. (1987) The total synthesis of avermectin A<sub>1a<\/sub>. J. Am. Chem. Soc. 111, 2967\u20132980.","DOI":"10.1021\/ja00190a034"},{"key":"176","doi-asserted-by":"crossref","unstructured":"176) White, J.D. and Bolton, G.L. (1990) Synthesis of avermectin B<sub>1a<\/sub> aglycon. J. Am. Chem. Soc. 112, 1626\u20131628.","DOI":"10.1021\/ja00160a051"},{"key":"177","doi-asserted-by":"crossref","unstructured":"177) Ley, S.V., Armstrong, A., Diez-Martin, D., Ford, M.J., Grice, P., Knight, J.G., Kolb, H.C., Madin, A., Marby, C.A., Mukherjee, S., Shaw, A.N., Slawin, A.M.Z., Vile, S., White, A.D., Williams, D.J. and Woods, M. (1991) Total synthesis of the anthelmintic macrolide avermectin B<sub>1a<\/sub>. J. Chem. Soc., Perkin Trans. 1, 667\u2013692.","DOI":"10.1039\/P19910000667"},{"key":"178","doi-asserted-by":"crossref","unstructured":"178) Crimmins, M.T., Al-awar, R.S., Vallin, I.M., Hollis, W.G. Jr., O\u2019Mahony, R., Lever, J.G. and Bankaitis-Davis, D.M. (1996) Asymmetric total synthesis of (+)-milbemycin D. J. Am. Chem. Soc. 118, 7513\u20137528.","DOI":"10.1021\/ja961071u"},{"key":"179","doi-asserted-by":"crossref","unstructured":"179) Hirama, M., Noda, T., Ito, S. and Kabuto, C. (1988) Stereocontrolled construction of the hexahydrobenzofuran subunit of the avermectins and the milbemycins: The aldol strategy. J. Org. Chem. 53, 706\u2013708.","DOI":"10.1021\/jo00238a047"},{"key":"180","doi-asserted-by":"crossref","unstructured":"180) Hirama, M., Nakamine, T. and Ito, S. (1986) Enantiospecific synthesis of the spiroacetal unit of avermectin B<sub>1a<\/sub>. Tetrahedron Lett. 27, 5281\u20135284.","DOI":"10.1016\/S0040-4039(00)85191-6"},{"key":"181","doi-asserted-by":"crossref","unstructured":"181) Hirama, M., Shimizu, M. and Iwashita, M. (1983) Enantiospecific syntheses of trifunctional (R)-3-hydroxy esters by baker\u2019s yeast reduction. J. Chem. Soc., Chem. Commun., 599\u2013600.","DOI":"10.1039\/c39830000599"},{"key":"182","doi-asserted-by":"crossref","unstructured":"182) Hirama, M., Noda, T. and Ito, S. (1985) Convenient synthesis of (S)-citronellol of high optical purity. J. Org. Chem. 50, 127\u2013129.","DOI":"10.1021\/jo00201a027"},{"key":"183","doi-asserted-by":"crossref","unstructured":"183) Hirama, M., Noda, T. and Ito, S. (1985) Convenient synthesis of (S)-citronellol of high optical purity (Additions and Corrections). J. Org. Chem. 50, 5916.","DOI":"10.1021\/jo00350a601"},{"key":"184","doi-asserted-by":"crossref","unstructured":"184) Hirama, M., Nakamine, T. and Ito, S. (1986) Trifunctional chiral synthons via stereocontrolled yeast reduction. Preparation of chiral pentene-1,3,5-triol derivatives. Chem. Lett., 1381\u20131384.","DOI":"10.1246\/cl.1986.1381"},{"key":"185","doi-asserted-by":"crossref","unstructured":"185) Lilitkarntakul, S., Hirama, M. and Ito, S. (1987) Diastereoselective deoxymercuration in acyclic system. A remarkable assistance by the neighboring carbonate group. Tetrahedron Lett. 28, 1207\u20131210.","DOI":"10.1016\/S0040-4039(00)95327-9"},{"key":"186","doi-asserted-by":"crossref","unstructured":"186) Hirama, M. and Shimizu, M. (1983) Oxidation of benzyl ether to benzoate by ozone. Synth. Commun. 13, 781\u2013786.","DOI":"10.1080\/00397918308063710"},{"key":"187","doi-asserted-by":"crossref","unstructured":"187) Hirama, M. and Uei, M. (1982) Carbamate mediated 1,3-asymmetric induction. A stereoselective synthesis of acyclic 1,3-diol systems. Tetrahedron Lett. 23, 5307\u20135310.","DOI":"10.1016\/S0040-4039(00)85825-6"},{"key":"188","doi-asserted-by":"crossref","unstructured":"188) Hirama, M., Iwashita, M., Yamazaki, Y. and Ito, S. (1984) Carbamate mediated functionalization of unsaturated alcohols II. Regio- and stereo-selective synthesis of 1,3-syn and 1,2-anti amino alcohol derivatives via iodocarbamation. Tetrahedron Lett. 25, 4963\u20134964.","DOI":"10.1016\/S0040-4039(01)91270-5"},{"key":"189","doi-asserted-by":"crossref","unstructured":"189) Hirama, M., Shigemoto, T., Yamazaki, Y. and Ito, S. (1985) Intramolecular Michael addition of O-carbamates to \u03b1,\u03b2-unsaturated esters. A new diastereoselective amination in an acyclic system. J. Am. Chem. Soc. 107, 1797\u20131798.","DOI":"10.1021\/ja00292a077"},{"key":"190","doi-asserted-by":"crossref","unstructured":"190) Hirama, M., Shigemoto, T. and Ito, S. (1985) Reversal of diastereofacial selectivity in the intramolecular Michael addition of \u03b4-carbamoyloxy-\u03b1,\u03b2-unsaturated esters. Synthesis of N-benzoyl-D,L-daunosamine. Tetrahedron Lett. 26, 4137\u20134140.","DOI":"10.1016\/S0040-4039(00)89313-2"},{"key":"191","doi-asserted-by":"crossref","unstructured":"191) Hirama, M., Nishizaki, I., Shigemoto, T. and Ito, S. (1986) New acyclic approach to 3-amino-2,3,6-trideoxy-L-hexoses: a stereocontrolled synthesis of N-benzoyl L-daunosamine. J. Chem. Soc., Chem. Commun., 393\u2013394.","DOI":"10.1039\/C39860000393"},{"key":"192","doi-asserted-by":"crossref","unstructured":"192) Hirama, M., Shigemoto, T. and Ito, S. (1987) Stereodivergent total synthesis of N-acetylacosamine and N-benzoylristosamine. J. Org. Chem. 52, 3342\u20133346.","DOI":"10.1021\/jo00391a032"},{"key":"193","doi-asserted-by":"crossref","unstructured":"193) Hirama, M., Iwakuma, T. and Ito, S. (1987) Diastereofacial selectivity in the intramolecular conjugate addition of a nitrogen nucleophile; stereocontrolled piperidine synthesis. J. Chem. Soc., Chem. Commun., 1523\u20131524.","DOI":"10.1039\/C39870001523"},{"key":"194","doi-asserted-by":"crossref","unstructured":"194) Hirama, M., Hioki, H., Ito, S. and Kabuto, C. (1988) Conjugate addition of internal nucleophile to chiral vinyl sulfoxides with stereogenic center at the allylic carbon. \u201cIntramolecular\u201d double asymmetric induction. Tetrahedron Lett. 29, 3121\u20133124.","DOI":"10.1016\/0040-4039(88)85102-5"},{"key":"195","doi-asserted-by":"crossref","unstructured":"195) Hirama, M., Hioki, H. and Ito, S. (1988) New entry to syn-\u03b2-hydroxy-\u03b1-amino acids. Tetrahedron Lett. 29, 3125\u20133128.","DOI":"10.1016\/0040-4039(88)85103-7"},{"key":"196","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.3987\/REV-88-SR5","volume":"28","author":"M. 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Soc. 101, 7013\u20137018.","DOI":"10.1021\/ja00517a039"},{"key":"199","doi-asserted-by":"crossref","unstructured":"199) Danishefsky, S., Berman, E., Clizbe, L.A. and Hirama, M. (1979) A simple synthesis of L-\u03b3-carboxyglutamate and derivative thereof. J. Am. Chem. Soc. 101, 4385\u20134386.","DOI":"10.1021\/ja00509a062"},{"key":"200","doi-asserted-by":"crossref","unstructured":"200) Danishefsky, S., Hirama, M., Gombatz, K., Harayama, T., Berman, E. and Schuda, P. (1978) Stereospecific total synthesis of dl-pentalenolactone. J. Am. Chem. Soc. 100, 6536\u20136538.","DOI":"10.1021\/ja00488a063"},{"key":"201","unstructured":"201) Masamune, S., Hirama, M., Mori, S., Ali, Sk.A. and Garvey, D.S. (1981) Total synthesis of 6-deoxyerythronolide B. J. Am. Chem. Soc. 103, 1568\u20131571."},{"key":"202","doi-asserted-by":"crossref","unstructured":"202) Hirama, M. and Uei, M. (1982) Chiral total synthesis of compactin. J. Am. Chem. Soc. 104, 4251\u20134253.","DOI":"10.1021\/ja00379a037"},{"key":"203","doi-asserted-by":"crossref","unstructured":"203) Hirama, M. and Iwashita, M. (1983) Total synthesis of (+)-monacolin K (mevinolin). Tetrahedron Lett. 24, 1811\u20131812.","DOI":"10.1016\/S0040-4039(00)81777-3"},{"key":"204","doi-asserted-by":"publisher","unstructured":"204) Oishi, T., Iwakuma, T., Hirama, M. and Ito, S. (1995) Stereoselective synthesis of (+)-swainsonine and (\u2212)-8,8a-di-epi-swainsonine. Synlett, 404\u2013406.","DOI":"10.1055\/s-1995-5002"},{"key":"205","doi-asserted-by":"crossref","unstructured":"205) Hirama, M., Oishi, T. and Ito, S. (1989) Asymmetric dihydroxylation of alkenes with osmium tetroxide: chiral N,N\u2032-dialkyl-2,2\u2032-bipyrrolidene complex. J. Chem. Soc., Chem. Commun., 665\u2013666.","DOI":"10.1039\/C39890000665"},{"key":"206","doi-asserted-by":"crossref","unstructured":"206) Oishi, T. and Hirama, M. 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Lett. 43, 349\u2013351.","DOI":"10.1246\/cl.131045"}],"container-title":["Proceedings of the Japan Academy, Series B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/pjab\/92\/8\/92_PJA9208B-08\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T00:47:35Z","timestamp":1498351655000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/pjab\/92\/8\/92_PJA9208B-08\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":226,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.2183\/pjab.92.290","relation":{},"ISSN":["0386-2208","1349-2896"],"issn-type":[{"value":"0386-2208","type":"print"},{"value":"1349-2896","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}