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Brief introduction of virtual reality          &amp; its challenges. Int J Sci Eng Res. 2013;4:304\u20139."},{"key":"2","doi-asserted-by":"crossref","unstructured":"[2]  Gregg L,Tarrier N. Virtual reality in mental          health: A review of the literature. Soc Psychiatry Psychiatr Epidemiol. 2007;42:343\u201354.          https:\/\/doi.org\/10.1007\/s00127-007-0173-4 PMID:17431528","DOI":"10.1007\/s00127-007-0173-4"},{"key":"3","doi-asserted-by":"crossref","unstructured":"[3]  Pollock A,Farmer SE,Brady MC,Langhorne P,Mead          GE,Mehrholz J,<i>et al.<\/i> Interventions for improving upper limb function          after stroke. Cochrane Libr. 2014;2014:CD010820.          https:\/\/doi.org\/10.1002\/14651858.CD010820.pub2 PMID:25387001","DOI":"10.1002\/14651858.CD010820.pub2"},{"key":"4","doi-asserted-by":"crossref","unstructured":"[4]  Maier M,Rubio Ballester B,Duff A,Duarte Oller          E,Verschure PFMJ. Effect of specific over nonspecific VR-based rehabilitation on          poststroke motor recovery: A systematic meta-analysis. Neurorehabil Neural Repair.          2019;33:112\u201329. https:\/\/doi.org\/10.1177\/1545968318820169 PMID:30700224","DOI":"10.1177\/1545968318820169"},{"key":"5","doi-asserted-by":"crossref","unstructured":"[5]  de Rooij IJM,van de Port IGL,Meijer JWG. Effect          of virtual reality training on balance and gait ability in patients with stroke:          Systematic review and meta-analysis. Phys Ther. 2016;96:1905\u201318.          https:\/\/doi.org\/10.2522\/ptj.20160054 PMID:27174255","DOI":"10.2522\/ptj.20160054"},{"key":"6","doi-asserted-by":"crossref","unstructured":"[6]  Dockx K,Bekkers EMJ,Van den Bergh V,Ginis          P,Rochester L,Hausdorff JM,<i>et al.<\/i> Virtual reality for rehabilitation in          Parkinson\u2019s disease. Cochrane Libr. 2016;12:CD010760.          https:\/\/doi.org\/10.1002\/14651858.CD010760.pub2 PMID:28000926","DOI":"10.1002\/14651858.CD010760.pub2"},{"key":"7","doi-asserted-by":"crossref","unstructured":"[7]  Garc\u00eda-Betances RI,Arredondo Waldmeyer MT,Fico          G,Cabrera-Umpi\u00e9rrez MF. A succinct overview of virtual reality technology use in          Alzheimer\u2019s disease. Front Aging Neurosci. 2015;7:80.          https:\/\/doi.org\/10.3389\/fnagi.2015.00080 PMID:26029101","DOI":"10.3389\/fnagi.2015.00080"},{"key":"8","doi-asserted-by":"crossref","unstructured":"[8]  Gianola S,Stucovitz E,Castellini G,Mascali          M,Vanni F,Tramacere I,<i>et al.<\/i> Effects of early virtual reality-based          rehabilitation in patients with total knee arthroplasty: A randomized controlled trial.          Medicine (Baltimore). 2020;99:e19136. https:\/\/doi.org\/10.1097\/MD.0000000000019136          PMID:32049833","DOI":"10.1097\/MD.0000000000019136"},{"key":"9","doi-asserted-by":"crossref","unstructured":"[9]  Ahn S,Hwang S. Virtual rehabilitation of upper          extremity function and independence for stoke: A meta-analysis. J Exerc Rehabil.          2019;15:358\u201369. https:\/\/doi.org\/10.12965\/jer.1938174.087 PMID:31316927","DOI":"10.12965\/jer.1938174.087"},{"key":"10","doi-asserted-by":"crossref","unstructured":"[10]  Lei C,Sunzi K,Dai F,Liu X,Wang Y,Zhang            B,<i>et al.<\/i> Effects of virtual reality rehabilitation training on gait and          balance in patients with Parkinson\u2019s disease: A systematic review. PLoS One.          2019;14:e0224819. https:\/\/doi.org\/10.1371\/journal.pone.0224819          PMID:31697777","DOI":"10.1371\/journal.pone.0224819"},{"key":"11","doi-asserted-by":"crossref","unstructured":"[11]  Laver KE,Lange B,George S,Deutsch JE,Saposnik          G,Crotty M. Virtual reality for stroke rehabilitation. Cochrane Libr. 2017;2018:CD008349.          https:\/\/doi.org\/10.1002\/14651858.CD008349.pub4 PMID:29156493","DOI":"10.1002\/14651858.CD008349.pub4"},{"key":"12","doi-asserted-by":"crossref","unstructured":"[12]  Freeman D,Reeve S,Robinson A,Ehlers A,Clark          D,Spanlang B,<i>et al.<\/i> Virtual reality in the assessment, understanding, and          treatment of mental health disorders. Psychol Med. 2017;47:2393\u2013400.          https:\/\/doi.org\/10.1017\/S003329171700040X PMID:28325167","DOI":"10.1017\/S003329171700040X"},{"key":"13","doi-asserted-by":"crossref","unstructured":"[13]  Bohil CJ,Alicea B,Biocca FA. Virtual reality in          neuroscience research and therapy. Nat Rev Neurosci. 2011;12:752\u201362.          https:\/\/doi.org\/10.1038\/nrn3122 PMID:22048061","DOI":"10.1038\/nrn3122"},{"key":"14","doi-asserted-by":"crossref","unstructured":"[14]  Huygelier H,Schraepen B,van Ee R,Vanden Abeele          V,Gillebert CR. Acceptance of immersive head-mounted virtual reality in older adults. Sci          Rep. 2019;9:4519. https:\/\/doi.org\/10.1038\/s41598-019-41200-6          PMID:30872760","DOI":"10.1038\/s41598-019-41200-6"},{"key":"15","doi-asserted-by":"crossref","unstructured":"[15]  Thiyagalingam S,Kulinski AE,Thorsteinsdottir          B,Shindelar KL,Takahashi PY. Dysphagia in older adults. Mayo Clin Proc. 2021;96:488\u201397.          https:\/\/doi.org\/10.1016\/j.mayocp.2020.08.001 PMID:33549267","DOI":"10.1016\/j.mayocp.2020.08.001"},{"key":"16","doi-asserted-by":"crossref","unstructured":"[16]  Takizawa C,Gemmell E,Kenworthy J,Speyer R. 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Acta Otorhinolaryngol Ital. 2016;36:386\u201394. https:\/\/doi.org\/10.14639\/0392-100X-770          PMID:27958599","DOI":"10.14639\/0392-100X-770"},{"key":"19","doi-asserted-by":"crossref","unstructured":"[19]  Hori K,Taniguchi H,Hayashi H,Magara J,Minagi          Y,Li Q,<i>et al.<\/i> Role of tongue pressure production in oropharyngeal swallow          biomechanics. Physiol Rep. 2013;1:e00167. https:\/\/doi.org\/10.1002\/phy2.167          PMID:24400166","DOI":"10.1002\/phy2.167"},{"key":"20","doi-asserted-by":"crossref","unstructured":"[20]  Yagi N,Oku Y,Nagami S,Yamagata Y,Kayashita          J,Ishikawa A,<i>et al.<\/i> Inappropriate timing of swallow in the respiratory          cycle causes breathing-swallowing discoordination. Front Physiol. 2017;8:676.          https:\/\/doi.org\/10.3389\/fphys.2017.00676 PMID:28970804","DOI":"10.3389\/fphys.2017.00676"},{"key":"21","doi-asserted-by":"crossref","unstructured":"[21]  Park J,Lee G,Jung Y. Effects of game-based chin          tuck against resistance exercise vs head-lift exercise in patients with dysphagia after          stroke: An assessor-blind, randomized controlled trial. J Rehabil Med. 2019;51:749\u201354.          https:\/\/doi.org\/10.2340\/16501977-2603 PMID:31515567","DOI":"10.2340\/16501977-2603"},{"key":"22","doi-asserted-by":"crossref","unstructured":"[22]  Pittara M,Matsangidou M,Pattichis CS. Virtual          reality for pulmonary rehabilitation: Comprehensive review. JMIR Rehabil Assist Technol.          2023;10:e47114. https:\/\/doi.org\/10.2196\/47114 PMID:37782529","DOI":"10.2196\/47114"},{"key":"23","doi-asserted-by":"crossref","unstructured":"[23]  Church S,Rogers E,Rockwood K,Theou O. A scoping          review of the Clinical Frailty Scale. BMC Geriatr. 2020;20:393.          https:\/\/doi.org\/10.1186\/s12877-020-01801-7 PMID:33028215","DOI":"10.1186\/s12877-020-01801-7"},{"key":"24","doi-asserted-by":"crossref","unstructured":"[24]  Hara K,Tohara H,Wada S,Iida T,Ueda K,Ansai T.          Jaw-opening force test to screen for Dysphagia: Preliminary results. Arch Phys Med          Rehabil. 2014;95:867\u201374. https:\/\/doi.org\/10.1016\/j.apmr.2013.09.005          PMID:24055575","DOI":"10.1016\/j.apmr.2013.09.005"},{"key":"25","unstructured":"[25]  Hayashi R,Tsuga K,Hosokawa R,Yoshida M,Sato          Y,Akagawa Y. A novel handy probe for tongue pressure measurement. Int J Prosthodont.          2002;15:385\u20138. PMID:12170854"},{"key":"26","doi-asserted-by":"crossref","unstructured":"[26]  Ueda T,Oki T,Ohta M,Ogami K,Sakurai K. Intra-          and inter-investigator reliability of measurement of lip-seal strength in adults. Bull          Tokyo Dent Coll. 2019;60:81\u20138. https:\/\/doi.org\/10.2209\/tdcpublication.2018-0038          PMID:30880298","DOI":"10.2209\/tdcpublication.2018-0038"},{"key":"27","doi-asserted-by":"crossref","unstructured":"[27]  Nishimura K,Nakayasu K,Kobayashi A,Mitsuma S.          Case identification of subjects with airflow limitations using the handheld spirometer          \u201cHi-Checker\u2122\u201d : Comparison against an electronic desktop spirometer. COPD. 2011;8:450\u20135.          https:\/\/doi.org\/10.3109\/15412555.2011.626817 PMID:22149406","DOI":"10.3109\/15412555.2011.626817"},{"key":"28","unstructured":"[28]  Tanigawa T,Sasaki T,Miyazaki A,Toshima K,Hiyama          A,Inami M. VR blowgun: Experience Design for Respiratory Rehabilitation Utilization          (Japanese); Oral Presentation at: Entertainment Computing Symposium 2022. Available from:          https:\/\/ipsj.ixsq.nii.ac.jp\/ej\/?action=repository_uri&amp;item_id=219487&amp;file_id=1&amp;file_no=1          [accessed 14 June 2024]"},{"key":"29","unstructured":"[29]  Yamano K,Sasaki T,Miyazaki A,Toshima K,Hiyama A.          VR blowgun: Respiratory rehabilitation using exhalation detection (Japanese); Oral          Presentation at: Entertainment Computing Symposium 2021. Available from:          https:\/\/ipsj.ixsq.nii.ac.jp\/ej\/?action=repository_uri&amp;item_id=212597&amp;file_id=1&amp;file_no=1          [accessed 14 June 2024]"},{"key":"30","doi-asserted-by":"crossref","unstructured":"[30]  Wang Z,Wang Z,Fang Q,Li H,Zhang L,Liu X. Effect          of expiratory muscle strength training on swallowing and cough functions in patients with          neurological diseases: A meta-analysis. Am J Phys Med Rehabil. 2019;98:1060\u20136.          https:\/\/doi.org\/10.1097\/PHM.0000000000001242 PMID:31180929","DOI":"10.1097\/PHM.0000000000001242"},{"key":"31","doi-asserted-by":"crossref","unstructured":"[31]  Zhang W,Pan H,Zong Y,Wang J,Xie Q. Respiratory          muscle training reduces respiratory complications and improves swallowing function after          stroke: A systematic review and meta-analysis. Arch Phys Med Rehabil. 2022;103:1179\u201391.          https:\/\/doi.org\/10.1016\/j.apmr.2021.10.020 PMID:34780729","DOI":"10.1016\/j.apmr.2021.10.020"},{"key":"32","doi-asserted-by":"crossref","unstructured":"[32]  Enright S,Chatham K,Ionescu AA,Unnithan VB,Shale          DJ. Inspiratory muscle training improves lung function and exercise capacity in adults          with cystic fibrosis. Chest. 2004;126:405\u201311. https:\/\/doi.org\/10.1378\/chest.126.2.405          PMID:15302725","DOI":"10.1378\/chest.126.2.405"},{"key":"33","doi-asserted-by":"crossref","unstructured":"[33]  Ma BD,Ng SL,Schwanen T,Zacharias J,Zhou          M,Kawachi I,<i>et al.<\/i> Pok\u00e9mon GO and physical activity in Asia: Multilevel          study. J Med Internet Res. 2018;20:e217. https:\/\/doi.org\/10.2196\/jmir.9670          PMID:29907559","DOI":"10.2196\/jmir.9670"},{"key":"34","doi-asserted-by":"crossref","unstructured":"[34]  Rand D,Kizony R,Weiss PTL. The Sony PlayStation          II EyeToy: Low-cost virtual reality for use in rehabilitation. J Neurol Phys Ther.          2008;32:155\u201363. https:\/\/doi.org\/10.1097\/NPT.0b013e31818ee779          PMID:19265756","DOI":"10.1097\/NPT.0b013e31818ee779"},{"key":"35","doi-asserted-by":"crossref","unstructured":"[35]  Flynn S,Palma P,Bender A. 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