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Int J Prosthodont. 2016;29:561\u20134.          https:\/\/doi.org\/10.11607\/ijp.4852 PMID:27824974","DOI":"10.11607\/ijp.4852"},{"key":"4","doi-asserted-by":"publisher","unstructured":"[4]  Kosaka T,Tsuji M,Kida M,Fushida S,Akema          S,Hasegawa D,<i>et al.<\/i> Quality of life and oral function in patients with          jaw defects following oral tumor surgery. Gerodontology. 2025;42:362\u201370.          https:\/\/doi.org\/10.1111\/ger.12800 PMID:39729624","DOI":"10.1111\/ger.12800"},{"key":"5","doi-asserted-by":"publisher","unstructured":"[5]  Limpuangthip N,Komin O. Association between oral          hypofunction and general health: A systematic review. BMC Oral Health. 2023;23:591.          https:\/\/doi.org\/10.1186\/s12903-023-03305-3 PMID:37620920","DOI":"10.1186\/s12903-023-03305-3"},{"key":"6","doi-asserted-by":"publisher","unstructured":"[6]  Akema S,Mameno T,Nakagawa T,Inagaki H,Hatta          K,Murotani Y,<i>et al.<\/i> Masticatory performance indicates the development of          psychological frailty: A 6-year prospective cohort study by the SONIC study group. J          Prosthodont Res. 2025;69:294\u2013302. https:\/\/doi.org\/10.2186\/jpr.JPR_D_23_00282          PMID:39756939","DOI":"10.2186\/jpr.JPR_D_23_00282"},{"key":"7","doi-asserted-by":"publisher","unstructured":"[7]  Kreeft AM,Krap M,Wismeijer D,Speksnijder          CM,Smeele LE,Bosch SD,<i>et al.<\/i> Oral function after maxillectomy and          reconstruction with an obturator. Int J Oral Maxillofac Surg. 2012;41:1387\u201392.          https:\/\/doi.org\/10.1016\/j.ijom.2012.07.014 PMID:22939876","DOI":"10.1016\/j.ijom.2012.07.014"},{"key":"8","doi-asserted-by":"publisher","unstructured":"[8]  Seignemartin CP,Miranda ME,Luz JGC,Teixeira RG.          Understandability of speech predicts quality of life among maxillectomy patients restored          with obturator prosthesis. J Oral Maxillofac Surg. 2015;73:2040\u20138.          https:\/\/doi.org\/10.1016\/j.joms.2015.04.031 PMID:26003777","DOI":"10.1016\/j.joms.2015.04.031"},{"key":"9","doi-asserted-by":"publisher","unstructured":"[9]  Dholam KP,Bachher G,Gurav SV. Changes in the          quality of life and acoustic speech parameters of patients in various stages of prosthetic          rehabilitation with an obturator after maxillectomy. 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J Prosthet Dent. 2017;118:108\u201312.          https:\/\/doi.org\/10.1016\/j.prosdent.2016.11.003 PMID:28089334","DOI":"10.1016\/j.prosdent.2016.11.003"},{"key":"12","doi-asserted-by":"publisher","unstructured":"[12]  Artopoulou II,Karademas EC,Papadogeorgakis          N,Papathanasiou I,Polyzois G. Effects of sociodemographic, treatment variables, and          medical characteristics on quality of life of patients with maxillectomy restored with          obturator prostheses. J Prosthet Dent. 2017;118:783\u2013789.e4.          https:\/\/doi.org\/10.1016\/j.prosdent.2017.01.021 PMID:28456369","DOI":"10.1016\/j.prosdent.2017.01.021"},{"key":"13","doi-asserted-by":"publisher","unstructured":"[13]  Keyf F. Obturator prostheses for          hemimaxillectomy patients. J Oral Rehabil. 2001;28:821\u20139.          https:\/\/doi.org\/10.1111\/j.1365-2842.2001.00754.x PMID:11580820","DOI":"10.1111\/j.1365-2842.2001.00754.x"},{"key":"14","doi-asserted-by":"publisher","unstructured":"[14]  Okay DJ,Genden E,Buchbinder D,Urken M.          Prosthodontic guidelines for surgical reconstruction of the maxilla: A classification          system of defects. J Prosthet Dent. 2001;86:352\u201363.          https:\/\/doi.org\/10.1067\/mpr.2001.119524 PMID:11677528","DOI":"10.1067\/mpr.2001.119524"},{"key":"15","doi-asserted-by":"publisher","unstructured":"[15]  Cao Y,Yu C,Liu W,Miao C,Han B,Yang J,<i>et            al.<\/i> Obturators versus flaps after maxillary oncological ablation: A systematic          review and best evidence synthesis. Oral Oncol. 2018;82:152\u201361.          https:\/\/doi.org\/10.1016\/j.oraloncology.2018.05.019 PMID:29909890","DOI":"10.1016\/j.oraloncology.2018.05.019"},{"key":"16","doi-asserted-by":"publisher","unstructured":"[16]  Artopoulou II,Sarafianou A,Perisanidis          C,Polyzois G. Effectiveness of prosthetic rehabilitation and quality of life of older          edentulous head and neck cancer survivors following resection of the maxilla: A          cross-sectional study. Support Care Cancer. 2022;30:4111\u201320.          https:\/\/doi.org\/10.1007\/s00520-022-06850-9 PMID:35067731","DOI":"10.1007\/s00520-022-06850-9"},{"key":"17","doi-asserted-by":"publisher","unstructured":"[17]  Aramany MA. Basic principles of obturator design          for partially edentulous patients. Part II: Design principles. J Prosthet Dent.          1978;40:656\u201362. https:\/\/doi.org\/10.1016\/0022-3913(78)90065-3 PMID:364026","DOI":"10.1016\/0022-3913(78)90065-3"},{"key":"18","doi-asserted-by":"publisher","unstructured":"[18]  Koyama S,Sasaki K,Inai T,Watanabe M. Effects of          defect configuration, size, and remaining teeth on masticatory function in          post\u2010maxillectomy patients. J Oral Rehabil. 2005;32:635\u201341.          https:\/\/doi.org\/10.1111\/j.1365-2842.2005.01483.x PMID:16102075","DOI":"10.1111\/j.1365-2842.2005.01483.x"},{"key":"19","doi-asserted-by":"publisher","unstructured":"[19]  Kawasaki M,Ogino Y,Moroi R,Ayukawa Y.          Comprehensive analyses of masticatory function in maxillectomy patients with functioning          removable prostheses: A retrospective cross-sectional study. J Clin Med. 2023;12:5117.          https:\/\/doi.org\/10.3390\/jcm12155117 PMID:37568519","DOI":"10.3390\/jcm12155117"},{"key":"20","doi-asserted-by":"publisher","unstructured":"[20]  Aramany MA. Basic principles of obturator design          for partially edentulous patients. Part I: Classification. J Prosthet Dent. 1978;40:554\u20137.          https:\/\/doi.org\/10.1016\/0022-3913(78)90092-6 PMID:364015","DOI":"10.1016\/0022-3913(78)90092-6"},{"key":"21","doi-asserted-by":"crossref","unstructured":"[21]  Minakuchi S,Tsuga K,Ikebe K,Ueda T,Tamura          F,Nagao K,<i>et al.<\/i> Oral hypofunction in the older population: Position          paper of the Japanese Society of Gerodontology in 2016. Gerodontology. 2018;35:317\u201324.          https:\/\/doi.org\/10.1111\/ger.12347 PMID:29882364","DOI":"10.1111\/ger.12347"},{"key":"22","doi-asserted-by":"publisher","unstructured":"[22]  Nokubi T,Yoshimuta Y,Nokubi F,Yasui S,Kusunoki          C,Ono T,<i>et al.<\/i> Validity and reliability of a visual scoring method for          masticatory ability using test gummy jelly. Gerodontology. 2013;30:76\u201382.          https:\/\/doi.org\/10.1111\/j.1741-2358.2012.00647.x PMID:22471409","DOI":"10.1111\/j.1741-2358.2012.00647.x"},{"key":"23","doi-asserted-by":"publisher","unstructured":"[23]  Hatanaka Y,Furuya J,Sato Y,Uchida Y,Shichita          T,Kitagawa N,<i>et al.<\/i> Associations between oral hypofunction tests, age,          and sex. 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Decreased tongue pressure is          associated with sarcopenia and sarcopenic dysphagia in the elderly. Dysphagia.          2015;30:80\u20137. https:\/\/doi.org\/10.1007\/s00455-014-9577-y PMID:25248988","DOI":"10.1007\/s00455-014-9577-y"},{"key":"27","doi-asserted-by":"publisher","unstructured":"[27]  Murotani Y,Hatta K,Takahashi T,Gondo Y,Kamide          K,Kabayama M,<i>et al.<\/i> Oral functions are associated with muscle strength          and physical performance in old-old Japanese. Int J Environ Res Public Health.          2021;18:13199. https:\/\/doi.org\/10.3390\/ijerph182413199 PMID:34948808","DOI":"10.3390\/ijerph182413199"},{"key":"28","doi-asserted-by":"publisher","unstructured":"[28]  Jabr CL,Oliveira LP,Campos LA,Campos JADB,de          Oliveira Lima AL,de Assis Mollo J\u00fanior F,<i>et al.<\/i> Handgrip force and bite          force in dentulous and edentulous individuals. J Oral Rehabil. 2023;50:664\u201370.          https:\/\/doi.org\/10.1111\/joor.13461 PMID:37036746","DOI":"10.1111\/joor.13461"},{"key":"29","doi-asserted-by":"publisher","unstructured":"[29]  Calixtre LB,Moreira RFC,Franchini          GH,Alburquerque-Send\u00edn F,Oliveira AB. Manual therapy for the management of pain and          limited range of motion in subjects with signs and symptoms of temporomandibular disorder:          A systematic review of randomised controlled trials. J Oral Rehabil. 2015;42:847\u201361.          https:\/\/doi.org\/10.1111\/joor.12321 PMID:26059857","DOI":"10.1111\/joor.12321"},{"key":"30","doi-asserted-by":"crossref","unstructured":"[30]  Namiki C,Hara K,Yanagida R,Nakagawa K,Yamaguchi          K,Okumura T,<i>et al.<\/i> Association between tongue pressure and jaw-opening          force in older adults. Int J Environ Res Public Health. 2022;19:9825.          https:\/\/doi.org\/10.3390\/ijerph19169825 PMID:36011461","DOI":"10.3390\/ijerph19169825"},{"key":"31","doi-asserted-by":"publisher","unstructured":"[31]  Tsuji M,Kosaka T,Kida M,Fushida S,Kasakawa          N,Fusayama A,<i>et al.<\/i> Factors related to masticatory performance in          patients with removable dentures for jaw defects following oral tumor surgery. J          Prosthodont Res. 2023;67:583\u20137. https:\/\/doi.org\/10.2186\/jpr.JPR_D_22_00204          PMID:36653126","DOI":"10.2186\/jpr.JPR_D_22_00204"},{"key":"32","doi-asserted-by":"publisher","unstructured":"[32]  Ikebe K,Matsuda K,Kagawa R,Enoki K,Yoshida          M,Maeda Y,<i>et al.<\/i> Association of masticatory performance with age, gender,          number of teeth, occlusal force and salivary flow in Japanese older adults: Is ageing a          risk factor for masticatory dysfunction? Arch Oral Biol. 2011;56:991\u20136.          https:\/\/doi.org\/10.1016\/j.archoralbio.2011.03.019 PMID:21529776","DOI":"10.1016\/j.archoralbio.2011.03.019"},{"key":"33","doi-asserted-by":"publisher","unstructured":"[33]  Kosaka T,Ono T,Kida M,Kikui M,Yamamoto M,Yasui            S,<i>et al.<\/i> A multifactorial model of masticatory performance: the Suita          study. J Oral Rehabil. 2016;43:340\u20137. https:\/\/doi.org\/10.1111\/joor.12371          PMID:26662207","DOI":"10.1111\/joor.12371"},{"key":"34","doi-asserted-by":"publisher","unstructured":"[34]  Kosaka T,Kida M,Kikui M,Hashimoto S,Fujii          K,Yamamoto M,<i>et al.<\/i> Factors influencing the changes in masticatory          performance: The Suita Study. JDR Clin Trans Res. 2018;3:405\u201312.          https:\/\/doi.org\/10.1177\/2380084418785863 PMID:30931790","DOI":"10.1177\/2380084418785863"},{"key":"35","doi-asserted-by":"publisher","unstructured":"[35]  Wang LM,Tian YY,Liu X,Cao Y,Sui L,Mao            C,<i>et al.<\/i> Quality of life in patients with cancer-related Brown IIb          maxillary defect: A comparison between conventional obturation rehabilitation and          submental flap reconstruction. Oral Oncol. 2022;132:105980.          https:\/\/doi.org\/10.1016\/j.oraloncology.2022.105980 PMID:35749804","DOI":"10.1016\/j.oraloncology.2022.105980"},{"key":"36","doi-asserted-by":"crossref","unstructured":"[36]  Corsalini M,Barile G,Catapano S,Ciocia          A,Casorelli A,Siciliani R,<i>et al.<\/i> Obturator prosthesis rehabilitation          after maxillectomy: Functional and aesthetical analysis in 25 patients. 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