{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T16:30:44Z","timestamp":1748968244618,"version":"3.41.0"},"reference-count":0,"publisher":"International Institute of Anticancer Research","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CDP"],"published-print":{"date-parts":[[2022,11,3]]},"abstract":"<jats:p>Background\/Aim: A novel mathematical diagnostic analysis using Fourier transform (FT) algorithm of the extrahepatic bile duct (BD) using magnetic resonance-cholangiography (MRC) was performed to evaluate irregularities of the bile duct lumen indicating BD cancer (BDC) extension compared to pancreatic head malignancies controls. Patients and Methods: BD lumen was automatically traced, and a 2D-diagram cross-section was measured and a FT-based integrated-power-spectral-density-function value (FTV) of both diameter and area (mm2 and mm4\/Hz) was calculated for cancerous and non-cancerous parts utilizing a computer workstation. Results: FT analysis that was achieved in 59 patients consisted of BDC in 31, pancreatic cancer with biliary stenosis (PC) in 10 and pancreatic neoplasm without stenosis (PN) in 18. FTV-diameter and -area of non-tumorous proximal BD were larger compared to tumor involving BD (p&lt;0.01), and those of the entire BD in BDCs were significantly larger than those in PN (p&lt;0.01). FTV-diameter and -area in proximal BDC-positive were smaller than those in BDC-negative (p&lt;0.05). BDC part was significantly discriminated by the cutoff value (286 mm2Hz\u20131 in diameter and 10,311 mm4Hz\u20131 in area) compared to PC and diagnostic accuracy was over 70% (p&lt;0.01). Conclusion: Novel mathematical MRC FT-analysis is promising for differentiating between BDC and PC with biliary stenosis and can be utilized as an objective diagnostic tool in the future.<\/jats:p>","DOI":"10.21873\/cdp.10158","type":"journal-article","created":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T14:51:16Z","timestamp":1668005476000},"page":"668-680","source":"Crossref","is-referenced-by-count":0,"title":["Novel Mathematical Diagnostic Analysis of Malignant Biliary Stenosis Using Magnetic Resonance Cholangiography in Patients Undergoing Pancreaticoduodenectomy"],"prefix":"10.21873","volume":"2","author":[{"given":"ATSUSHI","family":"NANASHIMA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MASANORI","family":"KOMI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NAOYA","family":"IMAMURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MASAHIDE","family":"HIYOSHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TAKEOMI","family":"HAMADA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YUUKI","family":"TSUCHIMOCHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NOBUHIKO","family":"ICHIKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MASAHIRO","family":"ENZAKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MINAKO","family":"AZUMA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"9336","published-online":{"date-parts":[[2022,11,3]]},"container-title":["Cancer Diagnosis &amp; Prognosis"],"original-title":[],"deposited":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T12:16:08Z","timestamp":1724933768000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cancerdiagnosisprognosis.org\/article\/153\/novel-mathematical-diagnostic-analysis-of-malignant-biliary-stenosis-using-magnetic-resonance-cholangiography-in-patients-undergoing-pancreaticoduodenectomy"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,3]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,11,3]]},"published-print":{"date-parts":[[2022,11,3]]}},"URL":"https:\/\/doi.org\/10.21873\/cdp.10158","relation":{},"ISSN":["2732-7787"],"issn-type":[{"type":"print","value":"2732-7787"}],"subject":[],"published":{"date-parts":[[2022,11,3]]}}}