{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T17:17:10Z","timestamp":1762363030113,"version":"build-2065373602"},"reference-count":0,"publisher":"International Institute of Anticancer Research","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CDP"],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:p>Background\/Aim: Plasmacytomas are neoplastic proliferations of plasma cells, usually presenting as solitary lesions distinct from multiple myeloma (MM). Solitary plasmacytomas in the oral cavity and head and neck are very rare, with limited data on clinical course and treatment response.\nCase Report: A 78-year-old woman presented with a solitary plasmacytoma on the palate. Imaging ruled out bone or systemic involvement. Pathology showed positivity for CD138, lambda light chain, CD79a, MUM1, Ki-67 (10-15%), and amyloid deposits. Although the patient received definitive radiation therapy (50 Gy\/25 fractions), residual disease remained. At the patient\u2019s request, six cycles of systemic chemotherapy with daratumumab, lenalidomide, and dexamethasone (DRd) were administered, leading to further shrinkage without complete response.\nConclusion: This rare case of solitary plasmacytoma showed residual disease post definitive radiotherapy. In those residual tumors, close long-term monitoring is crucial.<\/jats:p>","DOI":"10.21873\/cdp.10493","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T17:12:35Z","timestamp":1762362755000},"page":"772-778","source":"Crossref","is-referenced-by-count":0,"title":["Palatal Solitary Plasmacytoma: A Case Report on Post\u2010radiotherapy Challenges"],"prefix":"10.21873","volume":"5","author":[{"given":"MAYUKO","family":"YAMASHITA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOSHIHIKO","family":"KONDO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHINYA","family":"ENDO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NAO","family":"NISHIMURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YAWARA","family":"KAWANO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AKIYUKI","family":"HIROSUE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RYOJI","family":"YOSHIDA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HIDEKI","family":"NAKAYAMA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOSHIHIRO","family":"KOMOHARA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"9336","published-online":{"date-parts":[[2025,11,1]]},"container-title":["Cancer Diagnosis &amp; Prognosis"],"original-title":[],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T17:12:37Z","timestamp":1762362757000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cancerdiagnosisprognosis.org\/article\/548\/palatal-solitary-plasmacytoma-a-case-report-on-post-radiotherapy-challenges"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,1]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,11,1]]},"published-print":{"date-parts":[[2025,11,1]]}},"URL":"https:\/\/doi.org\/10.21873\/cdp.10493","relation":{},"ISSN":["2732-7787"],"issn-type":[{"value":"2732-7787","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,1]]}}}