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Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract. 2014;103:137–49.","DOI":"10.1016\/j.diabres.2013.11.002"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Bell JA, Kivimaki M, Hamer M. Metabolically healthy obesity and risk of incident type 2 diabetes: a meta-analysis of prospective cohort studies. Obes Rev. 2014;15:504–15.","DOI":"10.1111\/obr.12157"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Abdullah A, Peeters A, de Courten M, Stoelwinder J. The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies. Diabetes Res Clin Pract. 2010;89:309–19.","DOI":"10.1016\/j.diabres.2010.04.012"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393–403.","DOI":"10.1056\/NEJMoa012512"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Clark BC, Manini TM. Sarcopenia ≠ dynapenia. J Gerontol A Biol Sci Med Sci. 2008;63:829–34.","DOI":"10.1093\/gerona\/63.8.829"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Stenholm S, Härkänen T, Sainio P, Heliövaara M, Koskinen S. Long-term changes in handgrip strength in men and women—accounting the effect of right censoring due to death. J Gerontol A Biol Sci Med Sci. 2012;67:1068–74.","DOI":"10.1093\/gerona\/gls064"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Rantanen T, Masaki K, Foley D, Izmirlian G, White L, Guralnik JM. Grip strength changes over 27 yr in Japanese-American men. J Appl Physiol (1985). 1998;85:2047–53.","DOI":"10.1152\/jappl.1998.85.6.2047"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Hughes VA, Frontera WR, Wood M, Evans WJ, Dallal GE, Roubenoff R, et al. Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health. J Gerontol A Biol Sci Med Sci. 2001;56:B209–17.","DOI":"10.1093\/gerona\/56.5.B209"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Jackson AS, Janssen I, Sui X, Church TS, Blair SN. Longitudinal changes in body composition associated with healthy ageing: men, aged 20–96 years. Br J Nutr. 2012;107:1085–91.","DOI":"10.1017\/S0007114511003886"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Sayer AA, Syddall HE, Dennison EM, Martin HJ, Phillips DI, Cooper C, et al. Grip strength and the metabolic syndrome: findings from the Hertfordshire Cohort Study. QJM. 2007;100:707–13.","DOI":"10.1093\/qjmed\/hcm095"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Grøntved A, Pan A, Mekary RA, Stampfer M, Willett WC, Manson JE, et al. 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Committee of the Japan Diabetes Society on the Diagnostic Criteria of Diabetes Mellitus, Seino Y, Nanjo K, Tajima N, Kadowaki T, Kashiwagi A, Araki E, et al. Report of the committee on the classification and diagnostic criteria of diabetes mellitus. J Diabetes Investig. 2010;1:212–28.","DOI":"10.1111\/j.2040-1124.2010.00074.x"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Nomura T, Ikeda Y, Nakao S, Ito K, Ishida K, Suehiro T, et al. Muscle strength is a marker of insulin resistance in patients with type 2 diabetes: a pilot study. Endocr J. 2007;54:791–6.","DOI":"10.1507\/endocrj.K07-055"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Karelis AD, Tousignant B, Nantel J, Proteau-Labelle M, Malita FM, St-Pierre DH, et al. Association of insulin sensitivity and muscle strength in overweight and obese sedentary postmenopausal women. Appl Physiol Nutr Metab. 2007;32:297–301.","DOI":"10.1139\/H07-002"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Abbatecola AM, Ferrucci L, Ceda G, Russo CR, Lauretani F, Bandinelli S, et al. Insulin resistance and muscle strength in older persons. J Gerontol A Biol Sci Med Sci. 2005;60:1278–82.","DOI":"10.1093\/gerona\/60.10.1278"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Sayer AA, Dennison EM, Syddall HE, Gilbody HJ, Phillips DI, Cooper C. Type 2 diabetes, muscle strength, and impaired physical function: the tip of the iceberg? Diabetes Care. 2005;28:2541–2.","DOI":"10.2337\/diacare.28.10.2541"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Cetinus E, Buyukbese MA, Uzel M, Ekerbicer H, Karaoguz A. Hand grip strength in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract. 2005;70:278–86.","DOI":"10.1016\/j.diabres.2005.03.028"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Churilla JR, Magyari PM, Ford ES, Fitzhugh EC, Johnson TM. Muscular strengthening activity patterns and metabolic health risk among US adults. J Diabetes. 2012;4:77–84.","DOI":"10.1111\/j.1753-0407.2011.00172.x"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Cheng YJ, Gregg EW, De Rekeneire N, Williams DE, Imperatore G, Caspersen CJ, et al. Muscle-strengthening activity and its association with insulin sensitivity. Diabetes Care. 2007;30:2264–70.","DOI":"10.2337\/dc07-0372"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Jurca R, Lamonte MJ, Barlow CE, Kampert JB, Church TS, Blair SN. Association of muscular strength with incidence of metabolic syndrome in men. Med Sci Sports Exerc. 2005;37:1849–55.","DOI":"10.1249\/01.mss.0000175865.17614.74"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Kim TN, Park MS, Lim KI, Choi HY, Yang SJ, Yoo HJ, et al. Relationships between sarcopenic obesity and insulin resistance, inflammation, and vitamin D status: the Korean Sarcopenic Obesity Study. Clin Endocrinol (Oxf). 2013;78:525–32.","DOI":"10.1111\/j.1365-2265.2012.04433.x"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Stephen WC, Janssen I. Sarcopenic-obesity and cardiovascular disease risk in the elderly. J Nutr Health Aging. 2009;13:460–6.","DOI":"10.1007\/s12603-009-0084-z"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Wander PL, Boyko EJ, Leonetti DL, McNeely MJ, Kahn SE, Fujimoto WY. Greater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans. Diabetes Res Clin Pract. 2011;92:261–4.","DOI":"10.1016\/j.diabres.2011.01.007"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Schrager MA, Metter EJ, Simonsick E, Ble A, Bandinelli S, Lauretani F, et al. Sarcopenic obesity and inflammation in the InCHIANTI study. J Appl Physiol (1985). 2007;102:919–25.","DOI":"10.1152\/japplphysiol.00627.2006"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Croymans DM, Paparisto E, Lee MM, Brandt N, Le BK, Lohan D, et al. Resistance training improves indices of muscle insulin sensitivity and beta-cell function in overweight\/obese, sedentary young men. J Appl Physiol (1985). 2013;115:1245–53.","DOI":"10.1152\/japplphysiol.00485.2013"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Holten MK, Zacho M, Gaster M, Juel C, Wojtaszewski JF, Dela F. Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes. 2004;53:294–305.","DOI":"10.2337\/diabetes.53.2.294"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Park SW, Goodpaster BH, Lee JS, Kuller LH, Boudreau R, de Rekeneire N, et al. Excessive loss of skeletal muscle mass in older adults with type 2 diabetes. Diabetes Care. 2009;32:1993–7.","DOI":"10.2337\/dc09-0264"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Park SW, Goodpaster BH, Strotmeyer ES, Kuller LH, Broudeau R, Kammerer C, et al. Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes Care. 2007;30:1507–12.","DOI":"10.2337\/dc06-2537"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Watanabe T, Owashi K, Kanauchi Y, Mura N, Takahara M, Ogino T. The short-term reliability of grip strength measurement and the effects of posture and grip span. J Hand Surg Am. 2005;30:603–9.","DOI":"10.1016\/j.jhsa.2004.12.007"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Hamilton A, Balnave R, Adams R. Grip strength testing reliability. 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