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Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. <i>Lancet Infect Dis<\/i>. 2011;11(10):760\u2013768.","DOI":"10.1016\/S1473-3099(11)70090-1"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Hussain M, Melegaro A, Pebody RG, et\u00a0al. A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. <i>Epidemiol Infect<\/i>. 2005;133(5):891\u2013898.","DOI":"10.1017\/S0950268805004012"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Whitney CG, Farley MM, Hadler J, et\u00a0al; Active Bacterial Core Surveillance of the Emerging Infections Program Network. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. <i>N Engl J Med<\/i>. 2003;348(18):1737\u20131746.","DOI":"10.1056\/NEJMoa022823"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Schneider JL, Rowe JH, Garcia-de-Alba C, Kim CF, Sharpe AH, Haigis MC. The aging lung: Physiology, disease, and immunity. <i>Cell<\/i>. 2021;184(8):1990\u20132019.","DOI":"10.1016\/j.cell.2021.03.005"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Janssens JP, Krause KH. Pneumonia in the very old. <i>Lancet Infect Dis<\/i>. 2004;4(2):112\u2013124.","DOI":"10.1016\/S1473-3099(04)00931-4"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Davydow DS, Hough CL, Levine DA, Langa KM, Iwashyna TJ. Functional disability, cognitive impairment, and depression after hospitalization for pneumonia. <i>Am J Med<\/i>. 2013;126(7):615\u201324.e5.","DOI":"10.1016\/j.amjmed.2012.12.006"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Shah FA, Pike F, Alvarez K, et\u00a0al. Bidirectional relationship between cognitive function and pneumonia. <i>Am J Respir Crit Care Med<\/i>. 2013;188(5):586\u2013592.","DOI":"10.1164\/rccm.201212-2154OC"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Huang SS, Johnson KM, Ray GT, et\u00a0al. Healthcare utilization and cost of pneumococcal disease in the United States. <i>Vaccine<\/i>. 2011;29(18):3398\u20133412.","DOI":"10.1016\/j.vaccine.2011.02.088"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Falkenhorst G, Remschmidt C, Harder T, Hummers-Pradier E, Wichmann O, Bogdan C. Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis. <i>PLoS One<\/i>. 2017;12(1):e0169368.","DOI":"10.1371\/journal.pone.0169368"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Johnstone J, Marrie TJ, Eurich DT, Majumdar SR. Effect of pneumococcal vaccination in hospitalized adults with community-acquired pneumonia. <i>Arch Intern Med<\/i>. 2007;167(18):1938\u20131943.","DOI":"10.1001\/archinte.167.18.1938"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Ament A, Baltussen R, Duru G, et\u00a0al. Cost-effectiveness of pneumococcal vaccination of older people: a study in 5 western European countries. <i>Clin Infect Dis<\/i>. 2000;31(2):444\u2013450.","DOI":"10.1086\/313977"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Kawakami K, Ohkusa Y, Kuroki R, et\u00a0al. Effectiveness of pneumococcal polysaccharide vaccine against pneumonia and cost analysis for the elderly who receive seasonal influenza vaccine in Japan. <i>Vaccine<\/i>. 2010;28(43):7063\u20137069.","DOI":"10.1016\/j.vaccine.2010.08.010"},{"key":"27","unstructured":"27. European Centre for Disease Prevention and Control. 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