{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T09:31:55Z","timestamp":1777714315519,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1998,9,1]],"date-time":"1998-09-01T00:00:00Z","timestamp":904608000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Psychiatry Med"],"published-print":{"date-parts":[[1998,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Older patients have a high prevalence of neurological and psychiatric disorders. They also have a baseline prevalence of late latent syphilis or positive syphilis serology. Thus the clinical question arises as to whether a neuropsychiatric disorder in a geriatric patient is neurosyphilis or if the positive serology is incidental.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>An illustrative case example is used to illustrate this dilemma. The relevant literature is reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The cerebrospinal fluid (CSF) protein is an important indicator of inflammatory activity in the central nervous system and is used as a clinical guide in the diagnosis. Elderly patients have higher values of normal CSF protein than younger patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Given the importance of CSF protein in the diagnosis of neurosyphilis, physicians must include this knowledge, that elderly patients have higher CSF protein values, in their clinical decision making in the differentiation between neurosyphilis and late latent syphilis in the elderly patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2190\/cvl2-abc8-ut45-aft5","type":"journal-article","created":{"date-parts":[[2005,5,3]],"date-time":"2005-05-03T21:41:22Z","timestamp":1115156482000},"page":"333-339","source":"Crossref","is-referenced-by-count":3,"title":["The Elderly Psychiatric Patient with Positive Syphilis Serology: The Problem of Neurosyphilis"],"prefix":"10.1177","volume":"28","author":[{"given":"Ishwer L.","family":"Bharwani","sequence":"first","affiliation":[{"name":"State University of New York at Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles O.","family":"Hershey","sequence":"additional","affiliation":[{"name":"State University of New York at Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1998,9,1]]},"reference":[{"key":"bibr1-CVL2-ABC8-UT45-AFT5","unstructured":"Demographic and socioeconomic aspects of aging in the United States. Washington Bureau of the Census, Government Printing Office. 1984. 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Cerebrospinal fluid in disease of the nervous system. Philadelphia, PA: WB Saunders Co., 1980:186\u2013206."},{"key":"bibr17-CVL2-ABC8-UT45-AFT5","unstructured":"Harvey N. Mandel. Laboratory medicine in clinical practice. John Wright PSG Inc., 545 Grand Road, Littleton, Massachusetts 01460, US, 1983:264\u2013265."},{"key":"bibr18-CVL2-ABC8-UT45-AFT5","unstructured":"Wallach J. Interpretation of diagnostic tests. 5th Edition. Boston: Little Brown, 1991:217. Neurosyphilis."},{"key":"bibr19-CVL2-ABC8-UT45-AFT5","unstructured":"Mosby's diagnostic and laboratory test references. Mosby Yearbook, Inc., 1180 Westline Industrial Drive, St. Louis, Missouri 13646, p. 478."},{"key":"bibr20-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.3109\/00365517709091496"},{"key":"bibr21-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.3_Part_1.500"},{"key":"bibr22-CVL2-ABC8-UT45-AFT5","first-page":"251","volume":"26","author":"Kleine TO","year":"1993","journal-title":"Gerontology"},{"key":"bibr23-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(91)90218-V"},{"key":"bibr24-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230209"},{"issue":"1","key":"bibr25-CVL2-ABC8-UT45-AFT5","first-page":"36","volume":"47","author":"CDC","year":"1998","journal-title":"MMWR"},{"key":"bibr26-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1930.02720220007003"},{"key":"bibr27-CVL2-ABC8-UT45-AFT5","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410250108"}],"container-title":["The International Journal of Psychiatry in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2190\/CVL2-ABC8-UT45-AFT5","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2190\/CVL2-ABC8-UT45-AFT5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:11:35Z","timestamp":1777457495000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2190\/CVL2-ABC8-UT45-AFT5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,9]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,9]]}},"alternative-id":["10.2190\/CVL2-ABC8-UT45-AFT5"],"URL":"https:\/\/doi.org\/10.2190\/cvl2-abc8-ut45-aft5","relation":{},"ISSN":["0091-2174","1541-3527"],"issn-type":[{"value":"0091-2174","type":"print"},{"value":"1541-3527","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,9]]}}}