{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T10:38:35Z","timestamp":1779100715786,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Psychiatry Med"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of the research was to determine whether the administration of antidepressants, concurrently with antihypertensive therapy, leads to the better regulation of blood pressure in patients with hypertension and increased depressiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Research was conducted in two outpatient family clinics in Rijeka, Croatia, on 452 patients with arterial hypertension who had not been diagnosed with depression prior to the study. The diagnosis of hypertension was made in accordance with the European Society of Hypertension and the European Society of Cardiology Guidelines for the Management of Arterial Hypertension. Using the Beck Depression Inventory and the ICD-10 criteria for depression, a group of depressed hypertensive patients ( N = 134) was selected. Out of a total of 134 selected patients, 73 patients ( N = 73) were receiving antidepressants together with antihypertensives for 24 weeks. They formed the experimental group. The rest of the patients ( N = 61) continued to receive only antihypertensives and they formed the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>After the end of the 24-week therapy, the experimental group of patients had significantly lower levels of both systolic and diastolic blood pressure ( Z = 7.42; P &lt; 0.001; and Z = 7.36; P &lt; 0.001). The control group saw no significant difference between the level of blood pressure (both systolic and diastolic) prior to and after this period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The application of antidepressant therapy in patients with hypertension who are also depressed may be associated with the better control of blood pressure, which reduces the risk of cardiovascular disease in addition to alleviating depressive symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2190\/pm.47.2.c","type":"journal-article","created":{"date-parts":[[2014,5,30]],"date-time":"2014-05-30T21:15:11Z","timestamp":1401484511000},"page":"115-129","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Outcome of Treatment with Antidepressants in Patients with Hypertension and Undetected Depression"],"prefix":"10.1177","volume":"47","author":[{"given":"Ines","family":"Diminic-Lisica","sequence":"first","affiliation":[{"name":"University of Rijeka, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branislava","family":"Popovic","sequence":"additional","affiliation":[{"name":"University of Rijeka, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelena","family":"Rebic","sequence":"additional","affiliation":[{"name":"KBC Rijeka, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miro","family":"Klaric","sequence":"additional","affiliation":[{"name":"Mostar Clinical Hospital, Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Franci\u0161kovic","sequence":"additional","affiliation":[{"name":"University of Rijeka, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,5,30]]},"reference":[{"issue":"8","key":"bibr1-PM.47.2.c","first-page":"e003423","volume":"3","author":"Joffres M","year":"2013","journal-title":"British Medical Journal Open"},{"key":"bibr2-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61299-9"},{"key":"bibr3-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1185\/135525705X40373"},{"key":"bibr4-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2007.12.006"},{"key":"bibr5-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)70151-3"},{"key":"bibr6-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200018050-00003"},{"key":"bibr7-PM.47.2.c","first-page":"865","volume":"46","author":"Lukenda J","year":"2005","journal-title":"Croatian Medical Journal"},{"key":"bibr8-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.18.2363"},{"key":"bibr9-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1080\/10401230701653542"},{"key":"bibr10-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2011.13.1\/wkaton"},{"key":"bibr11-PM.47.2.c","first-page":"410","volume":"2","author":"Pickering T","year":"2000","journal-title":"Journal of Clinical Hypertension"},{"issue":"4","key":"bibr12-PM.47.2.c","first-page":"475","volume":"137","author":"Dois CA","year":"2009","journal-title":"Revista Medica de Chile"},{"key":"bibr13-PM.47.2.c","doi-asserted-by":"crossref","unstructured":"Huffman JC, Celano CM, Beach SR, Motiwala SR, Januzzi JL. Depression and cardiac disease: Epidemiology, mechanisms, and diagnosis. (Published online 2013 Apr 7 2013). Cardiovascular Psychiatry and Neurology 2013: 695925. doi: 10.1155\/2013\/695925.","DOI":"10.1155\/2013\/695925"},{"key":"bibr14-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/00001504-199905000-00013"},{"key":"bibr15-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.14.1725"},{"key":"bibr16-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7599.2010.00565.x"},{"key":"bibr17-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322005000300010"},{"key":"bibr18-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(03)00473-6"},{"key":"bibr19-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000077507.29863.CB"},{"key":"bibr20-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3283310ece"},{"key":"bibr21-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000106881.60228.16"},{"key":"bibr22-PM.47.2.c","doi-asserted-by":"crossref","unstructured":"H\u00e4fner S, Baumert J, Emeny RT, Lacruz ME, Bidlingmaier M, Reincke M, Kuenzel H, Holle R, Rupprecht R, Ladwig KH. Hypertension and depressed symptomatology: A cluster related to the activation of the renin-angiotensin-aldosterone system (RAAS). Findings from population based KORA F4 study. [published online ahead of print Apr 19 2013] Psychoneuroendocrinology 2013; pii: S0306-4530(13)00110-8. doi: 10.1016\/j.psyneuen.2013.03.015.","DOI":"10.1016\/j.psyneuen.2013.03.015"},{"key":"bibr23-PM.47.2.c","doi-asserted-by":"crossref","unstructured":"Krousel-Wood M, Islam T, Muntner P, Holt E, Joyce C, Morisky DE, Webber LS, Frohlich ED. Association of depression with antihypertensive medication adherence in older adults: Cross-sectional and longitudinal findings from CoSMO. Annals of Behavioral Medicine 2010; 248\u2013257.","DOI":"10.1007\/s12160-010-9217-1"},{"key":"bibr24-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1370\/afm.143"},{"key":"bibr25-PM.47.2.c","first-page":"313","volume":"34","author":"Duan S","year":"2009","journal-title":"Journal of Central South University (Med Sci)"},{"key":"bibr26-PM.47.2.c","first-page":"876","volume":"52","author":"Kisely S","year":"2006","journal-title":"Canadian Family Physician"},{"key":"bibr27-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3281fc975a"},{"key":"bibr28-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1961.01710120031004"},{"key":"bibr29-PM.47.2.c","first-page":"161","volume":"43","author":"Grubac P","year":"1989","journal-title":"Medical Archives"},{"key":"bibr30-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.12.011"},{"key":"bibr31-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199239467.001.0001"},{"key":"bibr32-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7445.939"},{"key":"bibr33-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-004-0722-z"},{"key":"bibr34-PM.47.2.c","first-page":"287","volume":"61","author":"Jelakovi\u0107 B","year":"2007","journal-title":"Acta Medica Croatica"},{"key":"bibr35-PM.47.2.c","first-page":"499","volume":"28","author":"Cortez-Dias N","year":"2009","journal-title":"Portuguese Journal of Cardiology"},{"key":"bibr36-PM.47.2.c","first-page":"265","volume":"10","author":"P\u00e9ter T","year":"2008","journal-title":"Neuropsychopharmacology in Hungary"},{"key":"bibr37-PM.47.2.c","first-page":"216","volume":"61","author":"Ghuloum S","year":"2011","journal-title":"Journal of the Pakistan Medical Association"},{"key":"bibr38-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200403000-00009"},{"key":"bibr39-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199509000-00004"},{"key":"bibr40-PM.47.2.c","first-page":"S28","volume":"17","author":"Elliott RL","year":"2007","journal-title":"Ethnicity and Disease"},{"key":"bibr41-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.8.1009"},{"key":"bibr42-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1159\/000026608"},{"key":"bibr43-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000085163.21752.0A"},{"key":"bibr44-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000185147.32385.4b"},{"key":"bibr45-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.9.1010"},{"key":"bibr46-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2008.04.025"},{"key":"bibr47-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-864121"},{"key":"bibr48-PM.47.2.c","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001063420109"},{"key":"bibr49-PM.47.2.c","first-page":"481","volume":"12","author":"Krousel-Wood M","year":"2010","journal-title":"Journal of Hypertension"}],"container-title":["The International Journal of Psychiatry in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2190\/PM.47.2.c","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2190\/PM.47.2.c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:13:50Z","timestamp":1777457630000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2190\/PM.47.2.c"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.2190\/PM.47.2.c"],"URL":"https:\/\/doi.org\/10.2190\/pm.47.2.c","relation":{},"ISSN":["0091-2174","1541-3527"],"issn-type":[{"value":"0091-2174","type":"print"},{"value":"1541-3527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2]]}}}