{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:09:57Z","timestamp":1789164597700,"version":"build-2803163510"},"reference-count":40,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Cancer"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiovascular disease and cancer are leading causes of morbidity and mortality worldwide, with cancer survivors facing elevated cardiovascular risk due to shared risk factors and cardiotoxic treatments. Physical activity (PA) is a well-established strategy to improve cardiovascular health and survivorship outcomes; however, most cancer survivors do not meet recommended PA guidelines. Understanding multilevel influences on PA engagement and promotion is essential to improving implementation in cardio-oncology care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to examine barriers and facilitators to PA engagement and promotion in cancer survivorship from both survivor and medical team perspectives using the Capability, Opportunity, Motivation-Behavior (COM-B) framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A descriptive qualitative study was conducted with 12 cancer survivors and 12 medical team members involved in oncology care. Semistructured interviews explored experiences, perceptions, and practices related to PA across the cancer care continuum. Rapid qualitative analysis was used to identify themes, which were mapped to COM-B domains. Participants also completed surveys assessing PA, cardiovascular health (Life\u2019s Essential 8 [LE8]), and sociodemographic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Survivors had a mean age of 65.3 (SD 12.6) years and were evenly distributed by sex. PA engagement varied, with 42% (5\/12) of survivors meeting recommended guidelines. The mean modified LE8-derived cardiovascular health score was 71.3 (SD 11.9), reflecting a standardized 6-domain composite (diet, PA, nicotine exposure, sleep, BMI, and blood pressure) calculated identically for all 12 participants. Across COM-B domains, physical limitation was the most commonly reported capability barrier (12\/12 survivors), while current engagement in PA was the most prevalent capability facilitator (12\/12 survivors). Opportunity was shaped by access to PA resources and social support, with social environment being the most frequently cited facilitator (12\/12 survivors; 9\/12 medical team members) and lack of access to PA resources being the most common barrier among medical team members (9\/12). Motivation reflected perceived health outcomes as the most prevalent facilitator across both groups (12\/12 survivors; 7\/12 medical team members), alongside competing concerns such as safety and emotional responses. Medical team members\u2019 ability to promote PA was influenced by survivor readiness, clinical context, and resource availability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PA engagement in cardio-oncology is shaped by dynamic interactions among capability, opportunity, and motivation across survivor and medical team member contexts. Although PA is widely valued, sustained engagement remains limited due to fluctuating symptoms, environmental constraints, and clinical uncertainties. Interventions should prioritize flexible, survivor-centered approaches and incorporate supportive clinical communication and resource alignment to enhance PA across the survivorship trajectory.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/104332","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:21:23Z","timestamp":1789161683000},"page":"e104332-e104332","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Physical Activity Engagement and Promotion Among Cancer Survivors in Cardio-Oncology Care: Qualitative Study"],"prefix":"10.2196","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2605-9614","authenticated-orcid":false,"given":"Macy K","family":"Tetrick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5235-7290","authenticated-orcid":false,"given":"Daniel","family":"Addison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8757-0658","authenticated-orcid":false,"given":"Rujul","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7263-4609","authenticated-orcid":false,"given":"Sara M","family":"St. George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4593-2202","authenticated-orcid":false,"given":"Vanina","family":"Pavia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anvitha","family":"Gogineni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3276-4411","authenticated-orcid":false,"given":"Peter","family":"Washington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7205-1427","authenticated-orcid":false,"given":"Sanam M","family":"Ghazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9877-5145","authenticated-orcid":false,"given":"Olivia","family":"Preston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3211-2691","authenticated-orcid":false,"given":"James L","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8634-6472","authenticated-orcid":false,"given":"Roberto M","family":"Benzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"issue":"16","key":"R1","doi-asserted-by":"publisher","first-page":"3029","DOI":"10.1002\/cncr.33587","article-title":"The ever-increasing importance of cancer as a leading cause of premature death worldwide","volume":"127","author":"Bray","journal-title":"Cancer"},{"issue":"15","key":"R2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.70057","article-title":"Cardiovascular mortality in people with cancer compared to the general population: a systematic review and meta-analysis","volume":"13","author":"Ng","journal-title":"Cancer Med"},{"issue":"9","key":"R3","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1038\/s41569-024-01017-x","article-title":"Cardiovascular disease and cancer: shared risk factors and mechanisms","volume":"21","author":"Wilcox","journal-title":"Nat Rev Cardiol"},{"issue":"48","key":"R4","doi-asserted-by":"publisher","first-page":"3889","DOI":"10.1093\/eurheartj\/ehz766","article-title":"A population-based study of cardiovascular disease mortality risk in US cancer patients","volume":"40","author":"Sturgeon","journal-title":"Eur Heart J"},{"issue":"2","key":"R5","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1093\/annonc\/mdw604","article-title":"Causes of death among cancer patients","volume":"28","author":"Zaorsky","journal-title":"Ann Oncol"},{"issue":"5","key":"R6","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-017-0846-x","article-title":"Cardiac complications of cancer therapy: pathophysiology, identification, prevention, treatment, and future directions","volume":"19","author":"Jain","journal-title":"Curr Cardiol Rep"},{"issue":"10","key":"R7","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1200\/JCO.2015.64.0409","article-title":"Cardiovascular disease among survivors of adult-onset cancer: a community-based retrospective cohort study","volume":"34","author":"Armenian","journal-title":"JCO"},{"issue":"3","key":"R8","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3322\/caac.21719","article-title":"American Cancer Society nutrition and physical activity guideline for cancer survivors","volume":"72","author":"Rock","journal-title":"CA Cancer J Clin"},{"issue":"7","key":"R9","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1158\/1055-9965.EPI-04-0703","article-title":"Controlled physical activity trials in cancer survivors: a systematic review and meta-analysis","volume":"14","author":"Schmitz","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"19","key":"R10","doi-asserted-by":"publisher","first-page":"2110","DOI":"10.1161\/CIRCULATIONAHA.107.729939","article-title":"Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms","volume":"116","author":"Mora","journal-title":"Circulation"},{"issue":"11","key":"R11","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1249\/MSS.0000000000002116","article-title":"Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable","volume":"51","author":"Campbell","journal-title":"Med Sci Sports Exerc"},{"issue":"4","key":"R12","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1093\/jn\/nxz268","article-title":"The World Cancer Research Fund\/American Institute for Cancer Research third expert report on diet, nutrition, physical activity, and cancer: impact and future directions","volume":"150","author":"Clinton","journal-title":"J Nutr"},{"issue":"6","key":"R13","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1001\/jamaoncol.2024.0470","article-title":"Adherence to American Cancer Society nutrition and physical activity guidelines among cancer survivors","volume":"10","author":"Baughman","journal-title":"JAMA Oncol"},{"issue":"12","key":"R14","doi-asserted-by":"publisher","first-page":"4087","DOI":"10.1007\/s00520-018-4279-x","article-title":"Are healthcare professionals being left in the lurch? The role of structural barriers and information resources to promote physical activity to cancer patients","volume":"26","author":"Haussmann","journal-title":"Support Care Cancer"},{"issue":"1","key":"R15","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s13187-015-0893-1","article-title":"Benefits and barriers of cancer practitioners discussing physical activity with their cancer patients","volume":"32","author":"Keogh","journal-title":"J Canc Educ"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.2196\/100279","article-title":"Cardiovascular symptom tracking among patients with cancer in cardio-oncology care: qualitative study using the capability, opportunity, motivation-behavior (COM-B) framework","volume":"12","author":"Benzo","journal-title":"JMIR Cancer"},{"issue":"41","key":"R17","doi-asserted-by":"publisher","first-page":"4229","DOI":"10.1093\/eurheartj\/ehac244","article-title":"2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS)","volume":"43","author":"Lyon","journal-title":"Eur Heart J"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-6-42","article-title":"The behaviour change wheel: a new method for characterising and designing behaviour change interventions","volume":"6","author":"Michie","journal-title":"Implement Sci"},{"issue":"6","key":"R19","doi-asserted-by":"publisher","first-page":"468","DOI":"10.3322\/caac.21579","article-title":"Exercise is medicine in oncology: engaging clinicians to help patients move through cancer","volume":"69","author":"Schmitz","journal-title":"CA A Cancer J Clinicians"},{"issue":"4","key":"R20","volume":"3","author":"Topolski","journal-title":"Prev Chronic Dis"},{"key":"R21","unstructured":"PRAPARE (protocol for responding to and assessing patients\u2019 assets, risks, and experiences). URL: https:\/\/prapare.org [Accessed 01-09-2026]"},{"issue":"5","key":"R22","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","article-title":"Life\u2019s essential 8: updating and enhancing the American Heart Association\u2019s construct of cardiovascular health: a presidential advisory from the American Heart Association","volume":"146","author":"Lloyd-Jones","journal-title":"Circulation"},{"issue":"5","key":"R23","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1111\/jhn.12451","article-title":"Evaluation of a dietary screener: the Mediterranean Eating Pattern for Americans tool","volume":"30","author":"Cerwinske","journal-title":"J Hum Nutr Diet"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2019.112516","article-title":"Qualitative methods in implementation research: an introduction","volume":"280","author":"Hamilton","journal-title":"Psychiatry Res"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1177\/16094069231164938","article-title":"Applying rapid qualitative analysis for health equity: lessons learned using \u201cEARS\u201d with Latino communities","volume":"22","author":"St George","journal-title":"Int J Qual Methods"},{"issue":"1","key":"R26","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s13012-024-01397-1","article-title":"Planning for and Assessing Rigor in Rapid Qualitative Analysis (PARRQA): a consensus-based framework for designing, conducting, and reporting","volume":"19","author":"Kowalski","journal-title":"Implementation Sci"},{"issue":"8","key":"R27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0220814","article-title":"Clinical factors associated with adherence to aerobic and resistance physical activity guidelines among cancer prevention patients and survivors","volume":"14","author":"Coletta","journal-title":"PLoS ONE"},{"issue":"8","key":"R28","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-024-08649-2","article-title":"Patient attitudes and experiences towards exercise during oncological treatment. A qualitative systematic review","volume":"32","author":"Finch","journal-title":"Support Care Cancer"},{"issue":"1","key":"R29","doi-asserted-by":"publisher","DOI":"10.1186\/s12904-020-00542-z","article-title":"Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patients","volume":"19","author":"Frikkel","journal-title":"BMC Palliat Care"},{"issue":"3","key":"R30","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s00520-017-3964-5","article-title":"Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review","volume":"26","author":"Clifford","journal-title":"Support Care Cancer"},{"issue":"14","key":"R31","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17142281","article-title":"Perceived barriers, facilitators, and needs related to promoting physical activity in cancer care: qualitative insights from oncology care providers","volume":"17","author":"Kumar","journal-title":"Cancers (Basel)"},{"issue":"3","key":"R32","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-026-10469-5","article-title":"Barriers and enablers to integrating physical activity in breast cancer care: a qualitative study using the TDF and COM-B model","volume":"34","author":"Piazzon","journal-title":"Support Care Cancer"},{"issue":"12","key":"R33","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.1249\/MSS.0000000000002735","article-title":"Home-based physical activity to alleviate fatigue in cancer survivors: a systematic review and meta-analysis","volume":"53","author":"Huizinga","journal-title":"Med Sci Sports Exerc"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2017.09.005","article-title":"Review: effectiveness of implementation strategies to increase physical activity uptake during and after cancer treatment","volume":"122","author":"IJsbrandy","journal-title":"Crit Rev Oncol Hematol"},{"issue":"5","key":"R35","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1007\/s11764-020-00963-y","article-title":"Social support and physical activity for cancer survivors: a qualitative review and meta-study","volume":"15","author":"McDonough","journal-title":"J Cancer Surviv"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2017.01.010","article-title":"Physical activity levels and counseling by health care providers in cancer survivors","volume":"99","author":"Tarasenko","journal-title":"Prev Med"},{"issue":"1","key":"R37","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-023-10003-x","article-title":"Exploring the practicality and acceptability a brief exercise communication and clinician referral pathway in cancer care: a feasibility study","volume":"23","author":"Caperchione","journal-title":"BMC Health Serv Res"},{"issue":"4","key":"R38","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-024-08457-8","article-title":"An initiative to implement a triage and referral system to make exercise and rehabilitation referrals standard of care in oncology","volume":"32","author":"Schmitz","journal-title":"Support Care Cancer"},{"issue":"16","key":"R39","doi-asserted-by":"publisher","first-page":"2846","DOI":"10.1002\/cncr.32143","article-title":"A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: the ACTIVATE trial","volume":"125","author":"Lynch","journal-title":"Cancer"},{"issue":"2","key":"R40","doi-asserted-by":"publisher","DOI":"10.1249\/TJX.0000000000000221","article-title":"A group-based, videoconference-delivered physical activity program for cancer survivors","volume":"8","author":"Leach","journal-title":"Transl J ACSM"}],"container-title":["JMIR Cancer"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:21:24Z","timestamp":1789161684000},"score":1,"resource":{"primary":{"URL":"https:\/\/cancer.jmir.org\/2026\/1\/e104332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":40,"URL":"https:\/\/doi.org\/10.2196\/104332","relation":{},"ISSN":["2369-1999"],"issn-type":[{"value":"2369-1999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]},"article-number":"v12i16e104332"}}