{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T04:23:52Z","timestamp":1793075032173,"version":"4.5.0"},"reference-count":54,"publisher":"JMIR Publications Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Formativ Res"],"abstract":"\n Background<\/jats:title>\n The speed of physiological recovery from stress may be a marker for cardiovascular disease risk. Stress management programs that incorporate guided breathing have been shown to moderate the stress response and augment recovery.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The aim of this study was to examine the effectiveness of an app-based brief relaxation intervention (BioBase) for facilitating physiological recovery in individuals exposed to a brief psychological stressor.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A total of 75 participants (44 women) completed a stressor speech task and were randomly assigned to one of three conditions: control, rumination, or an app-based relaxation breathing (BioBase) conditions. Heart rate variability (HRV) was assessed as a measure of autonomic function at baseline (6 min), during stress (6 min), and during recovery (6 min).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n There was a significant increase in subjective stress following stress exposure, but the ratings returned to baseline after recovery in all three groups. In addition, there was a significant decrease in vagally mediated HRV in the poststress period. During recovery, the root mean square of successive differences (P<.001), the percentage of successive interbeat (RR) intervals that differ by >50\u2009ms (pNN50; P<.001), and high-frequency (P<.02) HRV were significantly higher in the BioBase breathing condition than the rumination and control conditions. There was no difference in HRV values between the rumination and control conditions during recovery.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n App-based relaxed breathing interventions could be effective in reducing cardiovascular disease risk. These results provide additional utility of biofeedback breathing in augmenting physiological recovery from psychological stress.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/12227","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T18:30:49Z","timestamp":1540233049000},"page":"e12227","source":"Crossref","is-referenced-by-count":19,"title":["Use of a Biofeedback Breathing App to Augment Poststress Physiological Recovery: Randomized Pilot Study"],"prefix":"10.2196","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0476-3342","authenticated-orcid":false,"given":"David","family":"Plans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1041-6793","authenticated-orcid":false,"given":"Davide","family":"Morelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4337-1296","authenticated-orcid":false,"given":"Stefan","family":"S\u00fctterlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8774-7865","authenticated-orcid":false,"given":"Lucie","family":"Ollis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6776-3964","authenticated-orcid":false,"given":"Georgia","family":"Derbyshire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8483-1797","authenticated-orcid":false,"given":"Mark","family":"Cropley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000152"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.clinpsy.1.102803.144141"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2012.45"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-015-0630-8"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080\/10253890802046281"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1749-6632.1998.tb09546.x","volume":"840","author":"McEwen, B","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1997.tb02141.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000221285.50314.d3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-008-9152-9"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10111-018-0487-x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10484-014-9246-9"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-89208-3_324"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1037\/1089-2680.10.3.229"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/01.HYP.32.2.293","volume":"32","author":"Singh, JP","year":"1998","journal-title":"Hypertension"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.09.543"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus341"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-9450.2006.00527.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2008.08.004"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2010.06.015"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.01.032"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s10484-014-9253-x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10484-010-9133-y"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/joop.12115"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-016-2790-8"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1037\/ocp0000028"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1037\/a0026459"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.5288"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.7408"},{"key":"ref29","unstructured":"BioBeats2018-12-13BioBase: the guided wellbeing course \n https:\/\/biobeats.com\/biobase\/"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.20.2473"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e31817bbc77"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"ZoccolaPDickersonSLamSEmotion20122018-12-12Eliciting and maintaining ruminative thought: The role of social-evaluative threat \n http:\/\/doi.org\/10.1037\/a0027349","DOI":"10.1037\/a0027349"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)92596-3"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000031574.42041.23"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026395526858"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2011.07.004"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7967(99)00089-3"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.113.1.136"},{"key":"ref39","unstructured":"UrbaniakGPlousSResearch Randomizer (Version 4)http:\/\/www.randomizer.org\/"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.3758\/s13428-011-0107-7"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1990.tb01982.x"},{"issue":"3","key":"ref42","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","volume":"17","year":"1996","journal-title":"Eur Heart J"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2017.00258"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-118-6-199303150-00008"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1080\/13594320344000093"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2012.03.007"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00027"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1037\/bul0000036"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2014.01504"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1038\/nrn894"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005614"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nss066"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsu042"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-198807000-00009"}],"container-title":["JMIR Formative Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/formative.jmir.org\/2019\/1\/e12227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:58:33Z","timestamp":1782842313000},"score":1,"resource":{"primary":{"URL":"https:\/\/formative.jmir.org\/2019\/1\/e12227\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,11]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.2196\/12227","relation":{"has-preprint":[{"id-type":"doi","id":"10.2196\/preprints.12227","asserted-by":"object"}]},"ISSN":["2561-326X"],"issn-type":[{"value":"2561-326X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,11]]}}}