{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:47:40Z","timestamp":1787024860887,"version":"build-2736575974"},"reference-count":68,"publisher":"JMIR Publications Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Mhealth Uhealth"],"abstract":"\n Background<\/jats:title>\n Preventing and reducing substance use disorders, sexually transmitted infections (STIs)\/HIV, and teen pregnancy, and the associated risk behaviors (ie, substance use and sexual risk behaviors) among youth remain public health priorities in the United States. Equally important is improving the uptake of STI\/HIV testing among the youth. Mobile health (mHealth) apps may be a solution to ameliorate these public health concerns; however, few mHealth preventive interventions have demonstrated efficacy in reducing substance use or sexual risk behaviors or improving the uptake of STI\/HIV testing among the youth, particularly in clinic settings.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This small-scale study aimed to examine the feasibility of conducting a pilot randomized controlled trial (RCT). We evaluated the effects of Storytelling 4 Empowerment (S4E), relative to enhanced usual practice, on the potential mechanisms by which behavior change occurs, namely clinician-youth risk communication, prevention knowledge, and substance use and sexual risk refusal self-efficacy. We also assessed the ability to measure targeted outcomes of past 30-day substance use (ie, alcohol, tobacco, and other drug use), condomless sex, and alcohol or drug use before sex, as well as the uptake of STI\/HIV testing.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Employing community-based participatory research principles, 50 youths aged 13 to 21 years were recruited from a youth-centered community health clinic in Southeast Michigan, randomized sequentially to either S4E or enhanced usual practice, and assessed at baseline, immediately postintervention, and 30 days postintervention. S4E consists of 3 modules, including alcohol and drug use, tobacco, and STI\/HIV.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Relative to youth in the enhanced usual practice group, S4E participants demonstrated higher youth-clinician risk communication (mean 3.22, SD 1.67) and increases in prevention knowledge (\u2206 score mean 0.36, SD 0.51) and self-efficacy (\u2206 score mean 0.16, SD 0.47). In addition, youth in the S4E group showed reductions in the proportions of past 30-day overall substance use (Cohen h=0.71, 95% CI 0.15 to 1.27), as well as past 30-day alcohol (Cohen h=0.71, 95% CI 0.15 to 1.27), tobacco (Cohen h=0.17, 95% CI \u22120.39 to 0.73), and drug use (Cohen h=1.28, 95% CI 0.72 to 1.84). The results also suggest a reduction in the proportion of youths who reported past 30-day condomless sex (Cohen h=0.18, 95% CI \u22120.38 to 0.74) and alcohol use before sex (Cohen h=0.44, 95% CI \u22120.12 to 1.00). Finally, the findings also demonstrated an increase in the proportion of youths who reported STI\/HIV testing over time (Cohen h=0.16, 95% CI \u22120.39 to 0.72).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The findings suggest the feasibility of a small-scale pilot RCT. S4E demonstrated shifts in the hypothesized direction, reducing substance use, sexual risk behaviors, and improving the uptake of STI\/HIV testing among youth in a clinic setting. The findings suggest that a larger RCT may be warranted.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n ClinicalTrails.gov NCT03855410, https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03855410.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/16251","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T22:25:10Z","timestamp":1581373510000},"page":"e16251","source":"Crossref","is-referenced-by-count":35,"title":["Pilot Study of a Multilevel Mobile Health App for Substance Use, Sexual Risk Behaviors, and Testing for Sexually Transmitted Infections and HIV Among Youth: Randomized Controlled Trial"],"prefix":"10.2196","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9998-1934","authenticated-orcid":false,"given":"David","family":"Cordova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2114-2396","authenticated-orcid":false,"given":"Jaime","family":"Munoz-Velazquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8195-2454","authenticated-orcid":false,"given":"Frania","family":"Mendoza Lua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5408-5220","authenticated-orcid":false,"given":"Kathryn","family":"Fessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7494-5950","authenticated-orcid":false,"given":"Sydni","family":"Warner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0862-8436","authenticated-orcid":false,"given":"Jorge","family":"Delva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6168-4467","authenticated-orcid":false,"given":"Nicole","family":"Adelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Youth Leadership 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