{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:23:21Z","timestamp":1791959001316,"version":"4.3.4"},"reference-count":84,"publisher":"JMIR Publications Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Ment Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic back pain (CBP) is linked to a higher prevalence and higher occurrence of major depressive disorder (MDD) and can lead to reduced quality of life. Unfortunately, individuals with both CBP and recurrent MDD are underidentified. Utilizing health care insurance data may provide a possibility to better identify this complex population. In addition, internet- and mobile-based interventions might enhance the availability of existing treatments and provide help to those highly burdened individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This pilot randomized controlled trial investigated the feasibility of recruitment via the health records of a German health insurance company. The study also examined user satisfaction and effectiveness of a 9-week cognitive behavioral therapy and Web- and mobile-based guided self-help intervention Get.Back in CBP patients with recurrent MDD on sick leave compared with a waitlist control condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Health records from a German health insurance company were used to identify and recruit participants (N=76) via invitation letters. Study outcomes were measured using Web-based self-report assessments at baseline, posttreatment (9 weeks), and a 6-month follow-up. The primary outcome was depressive symptom severity (Center for Epidemiological Studies\u2013Depression); secondary outcomes included anxiety (Hamilton Anxiety and Depression Scale), quality of life (Assessment of Quality of Life), pain-related variables (Oswestry Disability Index, Pain Self-Efficacy Questionnaire, and pain intensity), and negative effects (Inventory for the Assessment of Negative Effects of Psychotherapy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The total enrollment rate with the recruitment strategy used was 1.26% (76\/6000). Participants completed 4.8 modules (SD 2.6, range 0-7) of Get.Back. The overall user satisfaction was favorable (mean Client Satisfaction Questionnaire score=24.5, SD 5.2). Covariance analyses showed a small but statistically significant reduction in depressive symptom severity in the intervention group (n=40) at posttreatment compared with the waitlist control group (n=36; F1,76=3.62, P=.03; d=0.28, 95% CI \u22120.17 to 0.74). Similar findings were noted for the reduction of anxiety symptoms (F1,76=10.45; P=.001; d=0.14, 95% CI \u22120.31 to 0.60) at posttreatment. Other secondary outcomes were nonsignificant (.06\u2264P\u2264.44). At the 6-month follow-up, the difference between the groups with regard to reduction in depressive symptom severity was no longer statistically significant (F1,76=1.50, P=.11; d=0.10, 95% CI \u22120.34 to 0.46). The between-group difference in anxiety at posttreatment was maintained to follow-up (F1,76=2.94, P=.04; d=0.38, 95% CI \u22120.07 to 0.83). There were no statistically significant differences across groups regarding other secondary outcomes at the 6-month follow-up (.08\u2264P\u2264.42).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results suggest that participants with comorbid depression and CBP on sick leave may benefit from internet- and mobile-based interventions, as exemplified with the positive user satisfaction ratings. The recruitment strategy via health insurance letter invitations appeared feasible, but more research is needed to understand how response rates in untreated individuals with CBP and comorbid depression can be increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>German Clinical Trials Register DRKS00010820; https:\/\/www.drks.de\/drks_web\/navigate.do? navigationId=trial.HTML&amp;TRIAL_ID=DRKS00010820.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/16398","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T09:45:43Z","timestamp":1586943943000},"page":"e16398","source":"Crossref","is-referenced-by-count":48,"title":["A Web- and Mobile-Based Intervention for Comorbid, Recurrent Depression in Patients With Chronic Back Pain on Sick Leave (Get.Back): Pilot Randomized Controlled Trial on Feasibility, User Satisfaction, and Effectiveness"],"prefix":"10.2196","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1340-2095","authenticated-orcid":false,"given":"Sandra","family":"Schlicker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2040-661X","authenticated-orcid":false,"given":"Harald","family":"Baumeister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4974-5455","authenticated-orcid":false,"given":"Claudia","family":"Buntrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4222-9837","authenticated-orcid":false,"given":"Lasse","family":"Sander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4593-6278","authenticated-orcid":false,"given":"Sarah","family":"Paganini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7021-3621","authenticated-orcid":false,"given":"Jiaxi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5903-4748","authenticated-orcid":false,"given":"Matthias","family":"Berking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5560-3605","authenticated-orcid":false,"given":"Dirk","family":"Lehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6820-0146","authenticated-orcid":false,"given":"David Daniel","family":"Ebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2020,4,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12018"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.01.022"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000323404"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.31887\/DCNS.2011.13.1\/wkaton","volume":"13","author":"Katon, WJ","year":"2011","journal-title":"Dialogues Clin Neurosci"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.20.2433"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2011.01.016"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2012.05.008"},{"key":"ref8","unstructured":"World Health Organization20182019-08-17GenevaWorld Health OrganizationGlobal Health Estimates 2016: Disease burden by Cause, Age, Sex, by Country and by Region, 2000-2016https:\/\/www.who.int\/healthinfo\/global_burden_disease\/estimates\/en\/index1.html"},{"key":"ref9","unstructured":"Statistisches BundesamtStatistisches Bundesamt20152019-08-17Gesundheit: Krankheitskostenhttps:\/\/www.destatis.de\/GPStatistik\/servlets\/MCRFileNodeServlet\/DEHeft_derivate_00033175\/2120721159004.pdf%3Bjsessionid%3DB19129ECF3A61F8DB331D847FC4E599C"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-5740-y"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7301.1511"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/16506073.2017.1420098"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2015.01.056"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.07.021"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2018.0659"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0b013e31824d90d4"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010152.pub2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000251"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2017.0681"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-1728"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-015226"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-017-1193-6"},{"key":"ref23","author":"First, MB","year":"1997","journal-title":"User's Guide for the Structured Clinical Interview for Dsm-IV Axis I Disorders"},{"key":"ref24","author":"Dilling, H","year":"2014","journal-title":"Internationale Klassifikation psychischer St\u00f6rungen: ICD-10 Kapitel V (F) - Klinisch-diagnostische Leitlinien"},{"key":"ref25","author":"Hautzinger, M","year":"1993","journal-title":"Allgemeine Depressionsskala (ADS): Manual Manual of the CES-D Scale"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"ref27","author":"Beck, AT","year":"1996","journal-title":"BDI-II, Beck Depression Inventory: Manual"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s00115-006-2098-7"},{"key":"ref29","author":"Wittchen, H","year":"1997","journal-title":"Strukturiertes Klinisches Interview f\u00fcr DSM-5 St\u00f6rungen \u2013 Klinische Version"},{"key":"ref30","unstructured":"Sealed Envelope2019-09-07London, UKSealed Envelope LTDCreate a Blocked Randomisation Listhttps:\/\/www.sealedenvelope.com\/simple-randomiser\/v1\/lists"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-13-217"},{"key":"ref32","unstructured":"Hakkaart-vanRLStratenATiemensBDonkerMResearch Gate20022019-08-17Rotterdam, The NetherlandsiMTAManual Trimbos\/iMTA Questionnaire for Costs Associated with Psychiatric Illness (TIC-P)https:\/\/www.researchgate.net\/publication\/254758194_Manual_TrimbosiMTA_Questionnaire_for_Costs_Associated_with_Psychiatric_Illness_TIC-P_in_Dutch"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3573"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1159\/000345967"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.4326"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-14-25"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1159\/000438673"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2018.06.007"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1326702"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.226"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-3223(02)01866-8"},{"key":"ref42","year":"2013","journal-title":"Diagnostic And Statistical Manual Of Mental Disorders"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-110203"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-10-38"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9903-x"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-013-0498-2"},{"key":"ref47","author":"Herrmann, C","year":"1995","journal-title":"HADS-D - Hospital Anxiety And Depression Scale"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-004-0815-0"},{"issue":"8","key":"ref50","first-page":"271","volume":"66","author":"Fairbank, JC","year":"1980","journal-title":"Physiotherapy"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200405000-00002"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200011150-00017"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1026\/0012-1924.55.2.84"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.12.008"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.11.1873"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.1.178"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-40095"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/0149-7189(79)90094-6"},{"issue":"7","key":"ref59","first-page":"248","volume":"39","author":"Schmidt, J","year":"1989","journal-title":"Psychother Psychosom Med Psychol"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.5952"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1159\/000367928"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1037\/\/0022-006x.59.1.12"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1080\/10503300500352500"},{"issue":"3","key":"ref64","first-page":"343","volume":"1","author":"Wilmers, F","year":"2008","journal-title":"Klin Diagnostik Eval"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1177\/0013164402062004008"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1080\/02331889108802322"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(00)04337-3"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989x.7.2.147"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.2307\/1164953"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbusres.2012.02.023"},{"key":"ref71","doi-asserted-by":"crossref","DOI":"10.1002\/9780470510445","author":"Molenberghs, G","year":"2007","journal-title":"Missing Data In Clinical Studies"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.12.065"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000616"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12275"},{"key":"ref75","author":"Steffanowski, A","year":"2007","journal-title":"Metaanalyse Der Effekte Psychosomatischer Rehabilitation. [Meta-Analysis on Effects of Psychosomatic Rehabilitation]"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1080\/10503300600919380"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1002\/da.22249"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.22823"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.1754"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.9925"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000118"},{"key":"ref82","unstructured":"ECB Statistical Data Warehouse2019-09-01European Central Bank - Statistical Data Warehouse - Quick Viewhttps:\/\/sdw.ecb.europa.eu\/quickview.do;jsessionid=5A9424640335F3F0569D5CFA4D531D4C?SERIES_KEY=120.EXR.D.USD.EUR.SP00.A&start=01-08-2019&end=31-08-2019&submitOptions.x=0&submitOptions.y=0&trans=N"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2016.10.011"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203127"}],"container-title":["JMIR Mental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/mental.jmir.org\/2020\/4\/e16398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:18:07Z","timestamp":1782839887000},"score":1,"resource":{"primary":{"URL":"http:\/\/mental.jmir.org\/2020\/4\/e16398\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,15]]},"references-count":84,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2196\/16398","relation":{},"ISSN":["2368-7959"],"issn-type":[{"value":"2368-7959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,15]]}}}