{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:59:36Z","timestamp":1782842376492,"version":"3.54.5"},"reference-count":30,"publisher":"JMIR Publications Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Mhealth Uhealth"],"abstract":"\n Background<\/jats:title>\n Foot temperature may increase after endovascular therapy, but the relationship between foot temperature and wound healing is unclear.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study was performed to evaluate the feasibility of a mobile health (mHealth)\u2013based thermometer for foot temperature monitoring in patients with chronic foot ulcer before and after endovascular therapy and to determine the association between temperature change and wound healing time.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This was a prospective cohort study. Patients who had a chronic foot ulcer (>3 months) and underwent endovascular therapy between July 2019 and December 2019 were included. The participants received standard medical care and endovascular therapy for revascularization. The mHealth-based thermometer, composed of 4 temperature-sensing chips, was put on the foot before and after endovascular therapy. Data from the chips were transferred to an associated mobile phone app via Bluetooth. Wound healing time was estimated using the Kaplan-Meier method, and the associations between baseline characteristics and clinical outcomes were evaluated using a Cox proportional hazard model.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 163 patients with chronic foot ulcer who underwent endovascular therapy were enrolled and followed up until wound healing was complete or for 180 days. The mean foot temperature before endovascular therapy was 30.6 (SD 2.8 \u00b0C). Foot temperature increased significantly (mean 32.1 \u00b0C, SD 2.8 \u00b0C; P=.01) after the procedure. Wound healing time was significantly different in the Kaplan-Meier curves of the patient group with temperature changes \u22652 \u00b0C and the group with temperature changes \u22642 \u00b0C (log-rank P<.001). A foot temperature increase \u22652 \u00b0C after endovascular therapy was associated with increased wound healing in univariate analysis (hazard ratio [HR] 1.78, 95% CI 1.24-2.76, P=.02), and the association remained significant in multivariate analysis (HR 1.69, 95% CI 1.21-2.67, P=.03).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The mHealth-based thermometer was feasible and useful for foot temperature monitoring, which may provide health care professionals with a new endpoint for endovascular therapy. Foot temperature increases \u22652 \u00b0C after endovascular therapy were associated with faster wound healing in patients with chronic foot ulcer. Further studies are needed, however, to confirm these findings.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/26468","type":"journal-article","created":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T10:30:55Z","timestamp":1620383455000},"page":"e26468","source":"Crossref","is-referenced-by-count":9,"title":["Mobile Health\u2013Based Thermometer for Monitoring Wound Healing After Endovascular Therapy in Patients With Chronic Foot Ulcer: Prospective Cohort Study"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5799-6513","authenticated-orcid":false,"given":"Donna Shu-Han","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-484X","authenticated-orcid":false,"given":"Jen-Kuang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2021,5,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.endien.2017.02.013"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v6.i1.62"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/268390"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.04.071"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.15829\/1560-4071-2018-8-164-221"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000470"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.08.014"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.23086"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/1526602814564370"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.002412"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1583\/14-4675MR.1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-14-0500"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/1538574419868863"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.07.020"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7547\/17-131"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"issue":"10","key":"ref17","first-page":"274","volume":"27","author":"Dini, V","year":"2015","journal-title":"Wounds"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475x.2000.00138.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2019-000696"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000383197.28192.98"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2196\/diabetes.8505"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-09828-4"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.21037\/mhealth.2019.12.01"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-016-1333-1"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-6899-6"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2019.100108"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.5436"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1177\/1060028020950726"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1583\/14-4721R.1"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.5718"}],"container-title":["JMIR mHealth and uHealth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/mhealth.jmir.org\/2021\/5\/e26468","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:37:08Z","timestamp":1782841028000},"score":1,"resource":{"primary":{"URL":"https:\/\/mhealth.jmir.org\/2021\/5\/e26468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,7]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2196\/26468","relation":{"has-preprint":[{"id-type":"doi","id":"10.2196\/preprints.26468","asserted-by":"object"}]},"ISSN":["2291-5222"],"issn-type":[{"value":"2291-5222","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,7]]}}}