{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:31:47Z","timestamp":1791963107038,"version":"4.3.4"},"reference-count":53,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"\n Background<\/jats:title>\n Aim2Be is a gamified lifestyle app designed to promote lifestyle behavior changes among Canadian adolescents and their families.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The primary aim was to test the efficacy of the Aim2Be app with support from a live coach to reduce weight outcomes (BMI Z score [zBMI]) and improve lifestyle behaviors among adolescents with overweight and obesity and their parents versus a waitlist control group over 3 months. The secondary aim was to compare health trajectories among waitlist control participants over 6 months (before and after receiving access to the app), assess whether support from a live coach enhanced intervention impact, and evaluate whether the app use influenced changes among intervention participants.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A 2-arm parallel randomized controlled trial was conducted from November 2018 to June 2020. Adolescents aged 10 to 17 years with overweight or obesity and their parents were randomized into an intervention group (Aim2Be with a live coach for 6 months) or a waitlist control group (Aim2Be with no live coach; accessed after 3 months). Adolescents\u2019 assessments at baseline and at 3 and 6 months included measured height and weight, 24-hour dietary recalls, and daily step counts measured with a Fitbit. Data on self-reported physical activity, screen time, fruit and vegetable intake, and sugary beverage intake of adolescents and parents were also collected.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 214 parent-child participants were randomized. In our primary analyses, there were no significant differences in zBMI or any of the health behaviors between the intervention and control groups at 3 months. In our secondary analyses, among waitlist control participants, zBMI (P=.02), discretionary calories (P=.03), and physical activity outside of school (P=.001) declined, whereas daily screen time increased (P<.001) after receiving access to the app compared with before receiving app access. Adolescents randomized to Aim2Be with live coaching reported more time being active outside of school compared with adolescents who used Aim2Be with no coaching over 3 months (P=.001). App use did not modify any changes in outcomes among adolescents in the intervention group.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The Aim2Be intervention did not improve zBMI and lifestyle behaviors in adolescents with overweight and obesity compared with the waitlist control group over 3 months. Future studies should explore the potential mediators of changes in zBMI and lifestyle behaviors as well as predictors of engagement.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n ClinicalTrials.gov NCT03651284; https:\/\/clinicaltrials.gov\/ct2\/show\/study\/NCT03651284<\/jats:p>\n <\/jats:sec>\n \n International Registered Report Identifier (IRRID)<\/jats:title>\n RR2-10.1186\/s13063-020-4080-2<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/38545","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T09:09:58Z","timestamp":1676970598000},"page":"e38545","source":"Crossref","is-referenced-by-count":22,"title":["Efficacy of the Aim2Be Intervention in Changing Lifestyle Behaviors Among Adolescents With Overweight and Obesity: Randomized Controlled Trial"],"prefix":"10.2196","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4598-9372","authenticated-orcid":false,"given":"Claire N","family":"Tugault-Lafleur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4782-9513","authenticated-orcid":false,"given":"Olivia","family":"De-Jongh Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7481-9505","authenticated-orcid":false,"given":"Janice","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6309-9816","authenticated-orcid":false,"given":"Jennifer","family":"Bradbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6424-5291","authenticated-orcid":false,"given":"Tom","family":"Warshawski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9432-3120","authenticated-orcid":false,"given":"Geoff D C","family":"Ball","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1737-256X","authenticated-orcid":false,"given":"Katherine","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0379-4427","authenticated-orcid":false,"given":"Josephine","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1958-2800","authenticated-orcid":false,"given":"Jill","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2598-3368","authenticated-orcid":false,"given":"Annick","family":"Buchholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2483-8791","authenticated-orcid":false,"given":"Louise","family":"M\u00e2sse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2023,4,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.24095\/hpcdp.36.9.03"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2010.222"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136\/adc.88.9.748"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S101631"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.07.049"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2011.08.005"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12334"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.8601"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12688"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012691"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2010.00803.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzh015"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/000992280604500408"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-021-00765-x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12002"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.5893"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-019-00356-y"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X19865855"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-020-4080-2"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c869"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2016-0151"},{"key":"ref24","unstructured":"Canada's Food GuideHealth Canada20192021-01-28https:\/\/food-guide.canada.ca\/en\/"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2013.03.359"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-013-9486-6"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.tb02378.x"},{"key":"ref28","unstructured":"Create a blocked randomisation listSealed Envelope Ltd20212021-06-05https:\/\/www.sealedenvelope.com\/simple-randomiser\/v1\/lists"},{"key":"ref29","unstructured":"Measuring children\u2019s height and weight accurately at homeCenter for Disease Control and Prevention20212021-06-07https:\/\/www.cdc.gov\/healthyweight\/assessing\/bmi\/childrens_bmi\/measuring_children.html"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckw133"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.2047-6310.2012.00064.x"},{"key":"ref32","unstructured":"IPEN adolescent survey for childrenInternational Physical Activity and the Environment Network20122021-06-07http:\/\/www.ipenproject.org\/methods_surveys.html"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.2196\/10338"},{"key":"ref34","unstructured":"Canadian community health survey (CCHS) - 2016Statistics Canada20182020-11-24https:\/\/www23.statcan.gc.ca\/imdb\/p3Instr.pl?Function=assembleInstr&lang=en&Item_Id=260675#qb269581"},{"key":"ref35","unstructured":"BRFSS questionnairesCenter for Disease Control and Prevention20212021-06-07https:\/\/www.cdc.gov\/brfss\/questionnaires\/index.htm"},{"key":"ref36","unstructured":"National youth physical activity and nutrition study (NYPANS)Center for Disease Control and Prevention20202021-06-07https:\/\/www.cdc.gov\/healthyyouth\/data\/yrbs\/nypans.htm"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3148\/70.4.2009.172"},{"key":"ref38","unstructured":"Eating well with Canada\u2019s food guideHealth Canada20072023-03-16https:\/\/publications.gc.ca\/collections\/Collection\/H164-38-1-2007E.pdf"},{"issue":"3","key":"ref39","first-page":"41","volume":"20","author":"Garriguet, D","year":"2009","journal-title":"Health Rep"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.3390\/nu10080985"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.328"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.158.4.385"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph8124662"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13373"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.9609"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.6972"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2021.101565"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.2196\/35285"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/s0031-3955(05)70347-3"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1080\/17477160600644272"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-014-9658-z"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-017-4220-0"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13331"}],"container-title":["Journal of Medical Internet Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jmir.org\/2023\/1\/e38545","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:34:41Z","timestamp":1782840881000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jmir.org\/2023\/1\/e38545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,25]]},"references-count":53,"URL":"https:\/\/doi.org\/10.2196\/38545","relation":{"has-preprint":[{"id-type":"doi","id":"10.2196\/preprints.38545","asserted-by":"object"}]},"ISSN":["1438-8871"],"issn-type":[{"value":"1438-8871","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,25]]}}}