{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:29:50Z","timestamp":1791836990009,"version":"4.3.4"},"reference-count":28,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Mhealth Uhealth"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Clinical guidelines for nonspecific low back pain (LBP) recommend self-management tailored to individual needs and capabilities as a first-line treatment. Mobile health solutions are a promising method for delivering tailored self-management interventions to patients with nonspecific LBP. However, it is not clear if the effectiveness of such self-management interventions depends on patients\u2019 initial pain characteristics. High pain intensity and long-term symptoms of LBP have been associated with an unfavorable prognosis, and current best evidence indicates that long-term LBP (lasting more than 3 months) requires a more extensive treatment approach compared to more acute LBP. The artificial intelligence\u2013based self\n                      <jats:sc>BACK<\/jats:sc>\n                      app supports tailored and evidence-based self-management of nonspecific LBP. In a recent randomized controlled trial, we showed that individuals who received the selfBACK app in addition to usual care had lower LBP-related disability at the 3-month follow-up compared to those who received usual care only. This effect was sustained at 6 and 9 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to explore if the baseline duration and intensity of LBP influence the effectiveness of the selfBACK intervention in a secondary analysis of the selfBACK randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In the selfBACK trial, 461 adults (18 years or older) who sought care for nonspecific LBP in primary care or at an outpatient spine clinic were randomized to receive the selfBACK intervention adjunct to usual care (n=232) or usual care alone (n=229). In this secondary analysis, the participants were stratified according to the duration of the current LBP episode at baseline (\u226412 weeks vs &gt;12 weeks) or baseline LBP intensity (\u22645 points vs &gt;5 points) measured by a 0-10 numeric rating scale. The outcomes were LBP-related disability measured by the Roland-Morris Disability Questionnaire (0- to 24-point scale), average LBP intensity, pain self-efficacy, and global perceived effect. To assess whether the duration and intensity of LBP influenced the effect of selfBACK\n                      <jats:sc>,<\/jats:sc>\n                      we estimated the difference in treatment effect between the strata at the 3- and 9-month follow-ups with a 95% CI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, there was no difference in effect for patients with different durations or intensities of LBP at either the 3- or 9-month follow-ups. However, there was suggestive evidence that the effect of the selfBACK intervention on LBP-related disability at the 3-month follow-up was largely confined to people with the highest versus the lowest LBP intensity (mean difference between the intervention and control group \u22121.8, 95% CI \u22123.0 to \u22120.7 vs 0.2, 95% CI \u22121.1 to 0.7), but this was not sustained at the 9-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results suggest that the intensity and duration of LBP have negligible influence on the effectiveness of the selfBACK intervention on LBP-related disability, average LBP intensity, pain self-efficacy, and global perceived effect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/40422","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T16:28:08Z","timestamp":1686328088000},"page":"e40422-e40422","source":"Crossref","is-referenced-by-count":19,"title":["The Role of Pain Duration and Pain Intensity on the Effectiveness of App-Delivered Self-Management for Low Back Pain (selfBACK): Secondary Analysis of a Randomized Controlled Trial"],"prefix":"10.2196","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6675-169X","authenticated-orcid":false,"given":"Anne Lovise","family":"Nordstoga","sequence":"first","affiliation":[{"name":"Norwegian University of Science and Technology","place":["Trondheim","Norway"],"department":["Department of Neuromedicine and Movement Science"]},{"name":"Trondheim University Hospital","place":["Trondheim","Norway"],"department":["Department of Physical Medicine and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4276-1345","authenticated-orcid":false,"given":"Lene","family":"Aasdahl","sequence":"additional","affiliation":[{"name":"Unicare Helsefort Rehabilitation Center","place":["Rissa","Norway"]},{"name":"Norwegian University of Science and Technology","place":["Trondheim","Norway"],"department":["Department of Public Health and Nursing"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8436-1046","authenticated-orcid":false,"given":"Louise Fleng","family":"Sandal","sequence":"additional","affiliation":[{"name":"University of Southern Denmark","place":["Odense","Denmark"],"department":["Department of Sports Science and Clinical Biomechanics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6632-7001","authenticated-orcid":false,"given":"Tina","family":"Dalager","sequence":"additional","affiliation":[{"name":"University of Southern Denmark","place":["Odense","Denmark"],"department":["Department of Sports Science and Clinical Biomechanics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4887-8288","authenticated-orcid":false,"given":"Atle","family":"Kongsvold","sequence":"additional","affiliation":[{"name":"Norwegian University of Science and Technology","place":["Trondheim","Norway"],"department":["Department of Public Health and Nursing"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3355-2680","authenticated-orcid":false,"given":"Paul Jarle","family":"Mork","sequence":"additional","affiliation":[{"name":"Norwegian University of Science and Technology","place":["Trondheim","Norway"],"department":["Department of Public Health and Nursing"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8251-3544","authenticated-orcid":false,"given":"Tom Ivar Lund","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Norwegian University of Science and Technology","place":["Trondheim","Norway"],"department":["Department of Public Health and Nursing"]},{"name":"Trondheim University Hospital","place":["Trondheim","Norway"],"department":["Clinic of Anaesthesia and Intensive Care"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"issue":"1","key":"R1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.mayocp.2012.08.020","article-title":"Why patients visit their doctors: assessing the most prevalent conditions in a defined American population","volume":"88","author":"St Sauver","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"R2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2474-11-144","article-title":"Annual consultation prevalence of regional musculoskeletal problems in primary care: an observational study","volume":"11","author":"Jordan","journal-title":"BMC Musculoskelet Disord"},{"issue":"10070","key":"R3","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/S0140-6736(16)30970-9","article-title":"Non-specific low back pain","volume":"389","author":"Maher","journal-title":"Lancet"},{"issue":"1","key":"R4","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/j.1532-2149.2012.00170.x","article-title":"Clinical course of non-specific low back pain: a systematic review of prospective cohort studies set in primary care","volume":"17","author":"Itz","journal-title":"Eur J Pain"},{"issue":"13","key":"R5","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1001\/jama.2010.344","article-title":"Will this patient develop persistent disabling low back pain?","volume":"303","author":"Chou","journal-title":"JAMA"},{"issue":"2","key":"R6","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/ejp.1679","article-title":"Evidence-based treatment recommendations for neck and low back pain across Europe: a systematic review of guidelines","volume":"25","author":"Corp","journal-title":"Eur J Pain"},{"issue":"2","key":"R7","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1136\/bjsports-2018-099878","article-title":"What does best practice care for musculoskeletal pain look like? Eleven consistent recommendations from high-quality clinical practice guidelines: systematic review","volume":"54","author":"Lin","journal-title":"Br J Sports Med"},{"issue":"11","key":"R8","doi-asserted-by":"publisher","first-page":"e287","DOI":"10.2196\/jmir.5692","article-title":"Can mobile phone apps influence people's health behavior change? An evidence review","volume":"18","author":"Zhao","journal-title":"J Med Internet Res"},{"issue":"10","key":"R9","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1001\/jamainternmed.2021.4097","article-title":"Effectiveness of app-delivered, tailored self-management support for adults with lower back pain-related disability: a selfBACK randomized clinical trial","volume":"181","author":"Sandal","journal-title":"JAMA Intern Med"},{"issue":"5","key":"R10","doi-asserted-by":"publisher","first-page":"e179","DOI":"10.2196\/jmir.7290","article-title":"Digital support interventions for the self-management of low back pain: a systematic review","volume":"19","author":"Nicholl","journal-title":"J Med Internet Res"},{"issue":"3","key":"R11","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.ejpain.2010.07.008","article-title":"Contributions of prognostic factors for poor outcome in primary care low back pain patients","volume":"15","author":"Dunn","journal-title":"Eur J Pain"},{"issue":"3","key":"R12","doi-asserted-by":"publisher","first-page":"e0229265","DOI":"10.1371\/journal.pone.0229265","article-title":"Prognostic indicators for poor outcomes in low back pain patients consulted in primary care","volume":"15","author":"Cruz","journal-title":"PLoS One"},{"issue":"1","key":"R13","doi-asserted-by":"publisher","first-page":"e919","DOI":"10.1097\/PR9.0000000000000919","article-title":"Prognostic factors for pain chronicity in low back pain: a systematic review","volume":"6","author":"Nieminen","journal-title":"Pain Rep"},{"issue":"2","key":"R14","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.berh.2009.12.005","article-title":"What is the prognosis of back pain?","volume":"24","author":"Hayden","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"10137","key":"R15","doi-asserted-by":"publisher","first-page":"2368","DOI":"10.1016\/S0140-6736(18)30489-6","article-title":"Prevention and treatment of low back pain: evidence, challenges, and promising directions","volume":"391","author":"Foster","journal-title":"Lancet"},{"issue":"12","key":"R16","doi-asserted-by":"publisher","first-page":"e14720","DOI":"10.2196\/14720","article-title":"An app-delivered self-management program for people with low back pain: protocol for the selfBACK randomized controlled trial","volume":"8","author":"Sandal","journal-title":"JMIR Res Protoc"},{"issue":"1","key":"R17","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3233\/AIC-1994-7104","article-title":"Case-based reasoning: foundational issues, methodological variations, and system approaches","volume":"7","author":"Aamodt","journal-title":"AI Commun"},{"key":"R18","doi-asserted-by":"crossref","unstructured":"Bach K Szczepanski T Aamodt A Gundersen OE Mork PJ . Case representation and similarity assessment in the self BACK decision support system. Goel A D\u00edaz-Agudo M Roth-Berghofer T , editors. Case-Based Reasoning Research and Development ICCBR 2016 Lecture Notes in Computer Science. Vol 9969. Cham: Springer; 2016. [10.1007\/978-3-319-47096-2_3]","DOI":"10.1007\/978-3-319-47096-2_3"},{"issue":"7","key":"R19","doi-asserted-by":"publisher","first-page":"e167","DOI":"10.2196\/resprot.9379","article-title":"A decision support system to enhance self-management of low back pain: protocol for the selfBACK project","volume":"7","author":"Mork","journal-title":"JMIR Res Protoc"},{"issue":"2","key":"R20","doi-asserted-by":"publisher","first-page":"e18729","DOI":"10.2196\/18729","article-title":"Usability and acceptability of an app (SELFBACK) to support self-management of low back pain: mixed methods study","volume":"7","author":"Nordstoga","journal-title":"JMIR Rehabil Assist Technol"},{"issue":"1","key":"R21","doi-asserted-by":"publisher","first-page":"e26555","DOI":"10.2196\/26555","article-title":"Using intervention mapping to develop a decision support system-based smartphone app (selfBACK) to support self-management of nonspecific low back pain: development and usability study","volume":"24","author":"Svendsen","journal-title":"J Med Internet Res"},{"issue":"24","key":"R22","doi-asserted-by":"publisher","first-page":"3115","DOI":"10.1097\/00007632-200012150-00006","article-title":"The Roland\u2013Morris Disability Questionnaire and the Oswestry Disability Questionnaire","volume":"25","author":"Roland","journal-title":"Spine"},{"issue":"S11","key":"R23","doi-asserted-by":"publisher","first-page":"S240","DOI":"10.1002\/acr.20543","article-title":"Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP)","volume":"63","author":"Hawker","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"2","key":"R24","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.ejpain.2005.12.008","article-title":"The pain self-efficacy questionnaire: taking pain into account","volume":"11","author":"Nicholas","journal-title":"Eur J Pain"},{"issue":"3","key":"R25","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1179\/jmt.2009.17.3.163","article-title":"Global rating of change scales: a review of strengths and weaknesses and considerations for design","volume":"17","author":"Kamper","journal-title":"J Man Manip Ther"},{"issue":"1","key":"R26","first-page":"134","volume":"62","author":"Liang","journal-title":"Sankhy\u0101 Indian J Stat Ser B"},{"issue":"20","key":"R27","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1002\/sim.3639","article-title":"Should baseline be a covariate or dependent variable in analyses of change from baseline in clinical trials?","volume":"28","author":"Liu","journal-title":"Stat Med"},{"issue":"22","key":"R28","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1136\/bjsports-2017-097810","article-title":"NICE low back pain guidelines: opportunities and obstacles to change practice","volume":"51","author":"O\u2019Sullivan","journal-title":"Br J Sports Med"}],"container-title":["JMIR mHealth and uHealth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/mhealth.jmir.org\/2023\/1\/e40422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:38:52Z","timestamp":1782841132000},"score":1,"resource":{"primary":{"URL":"https:\/\/mhealth.jmir.org\/2023\/1\/e40422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":28,"URL":"https:\/\/doi.org\/10.2196\/40422","relation":{"has-preprint":[{"id-type":"doi","id":"10.2196\/preprints.40422","asserted-by":"object"}]},"ISSN":["2291-5222"],"issn-type":[{"value":"2291-5222","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]},"article-number":"v11i1e40422"}}