{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:58:52Z","timestamp":1782842332654,"version":"3.54.5"},"reference-count":65,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Co-use of alcohol and e-cigarettes (often called vaping) has been linked with long-term health outcomes, including increased risk for substance use disorder. Co-use may have been exacerbated by the COVID-19 pandemic. Social networking sites may offer insights into current perspectives on polysubstance use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aims of this study were to investigate concurrent mentions of vaping and alcohol on Twitter (subsequently rebranded X) during a time of changing vaping regulations in the United States and the emergence of the COVID-19 pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Tweets including both vape- and alcohol-related terms posted between October 2019 and September 2020 were analyzed using latent Dirichlet allocation modeling. Distinct topics were identified and described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three topics were identified across 6437 tweets: (1) flavors and flavor ban (n=3334, 51.8% of tweets), (2) co-use discourse (n=1119, 17.4%), and (3) availability and access regulation (n=1984, 30.8%). Co-use discussions often portrayed co-use as positive and prosocial. Tweets focused on regulation often used alcohol regulations for comparison. Some focused on the perceived overregulation of vaping (compared to alcohol), while others supported limiting youth access but not at the expense of adult access (eg, stronger age verification over product bans). Across topics, vaping was typically portrayed as less harmful than alcohol use. The benefits of flavors for adult smoking cessation were also discussed. The distribution of topics across time varied across both pre\u2013 and post\u2013regulatory change and pre\u2013 and post\u2013COVID-19 pandemic declaration periods, suggesting shifts in topic focus salience across time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Co-use discussions on social media during this time of regulatory change and social upheaval typically portrayed both vaping and alcohol use in a positive light. It also included debates surrounding the differences in regulation of the 2 substances\u2014particularly as it related to limiting youth access. Emergent themes from the analysis suggest that alcohol was perceived as more harmful but less regulated and more accessible to underage youth than vaping products. Frequent discussions and comparisons of the 2 substances as it relates to their regulation emphasize the still-evolving vaping policy landscape. Social media content analyses during times of change may help regulators and policy makers to better understand and respond to common concerns and potential misconceptions surrounding drug-related policies and accessibility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/51870","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T16:30:49Z","timestamp":1731429049000},"page":"e51870","source":"Crossref","is-referenced-by-count":2,"title":["Concurrent Mentions of Vaping and Alcohol on Twitter: Latent Dirichlet Analysis"],"prefix":"10.2196","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7928-2781","authenticated-orcid":false,"given":"Lynsie R","family":"Ranker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3836-5008","authenticated-orcid":false,"given":"David Assefa","family":"Tofu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7850-3423","authenticated-orcid":false,"given":"Manyuan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5004-9492","authenticated-orcid":false,"given":"Jiaxi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6818-0384","authenticated-orcid":false,"given":"Aruni","family":"Bhatnagar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8855-0933","authenticated-orcid":false,"given":"Rose Marie","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-4703","authenticated-orcid":false,"given":"Derry","family":"Wijaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9107-1880","authenticated-orcid":false,"given":"Traci","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9286-7538","authenticated-orcid":false,"given":"Jessica L","family":"Fetterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6139-4785","authenticated-orcid":false,"given":"Ziming","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.su6901a7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7145a1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1080\/00952990.2020.1771723"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2019.01.011"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2018.11.013"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2022.109594"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000069"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2020.106400"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/add.12829"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/add.14547"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1080\/00952990.2016.1193511"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7034a3"},{"key":"ref13","unstructured":"Addiction and healthNational Institute on Drug Abuse2024-05-08https:\/\/nida.nih.gov\/publications\/drugs-brains-behavior-science-addiction\/addiction-health"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2015.05.031"},{"key":"ref15","unstructured":"e-Cigarette use among youth and young adults: a report of the Surgeon GeneralUS Department of Health and Human Services20162024-09-11https:\/\/www.cdc.gov\/tobacco\/sgr\/e-cigarettes\/pdfs\/2016_sgr_entire_report_508.pdf"},{"key":"ref16","unstructured":"Surgeon General\u2019s Advisory on e-cigarette use among youth: the e-cigarette epidemic among youthUS Department of Health and Human Services. 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