{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:58:56Z","timestamp":1782842336163,"version":"3.54.5"},"reference-count":46,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Mhealth Uhealth"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Hypertension is highly prevalent among patients undergoing hemodialysis, with a significant proportion experiencing poorly controlled blood pressure (BP). Digital BP management in this population has been underused.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study aimed to explore the efficacy of a web-based home BP monitoring (HBPM) program in improving predialysis BP control and enhancing knowledge, perception, and adherence to HBPM among patients with hypertension undergoing hemodialysis.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A multicenter, open-label, randomized controlled trial was conducted at 2 hemodialysis units. Patients were randomly allocated in a 1:1 ratio to either the web-based HBPM program as the intervention group or to usual care as the control group over a 6-month period. The primary outcomes were the predialysis BP control rate, defined as less than 140\/90 mm Hg, and the predialysis systolic and diastolic BP, assessed from baseline to the 6-month follow-up. Secondary outcomes included patient knowledge, perception, and adherence to HBPM, evaluated using the HBPM Knowledge Questionnaire, HBPM Perception Scale, and HBPM Adherence Scale, respectively. A generalized estimating equations analysis was used to analyze the primary outcomes in the intention-to-treat analysis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the 165 patients enrolled in the program (n=84, 50.9% in the web-based HBPM group and n=81, 49.1% in the control group), 145 (87.9%) completed the follow-up assessment. During the follow-up period, 11 instances of hypotension occurred in 9 patients in the web-based HBPM group, compared to 15 instances in 14 patients in the control group. The predialysis BP control rate increased from 30% (25\/84) to 48% (40\/84) in the web-based HBPM group after the 6-month intervention, whereas in the control group, it decreased from 37% (30\/81) to 25% (20\/81;\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n 2<\/jats:sub>\n =16.82,\n P<\/jats:italic>\n <.001; odds ratio 5.11, 95% CI 2.14-12.23,\n P<\/jats:italic>\n <.001). The web-based HBPM group demonstrated a significant reduction after the 6-month intervention in the predialysis systolic BP (\n t<\/jats:italic>\n 163<\/jats:sub>\n =2.46,\n P<\/jats:italic>\n =.02; \u03b2=\u22126.09, 95 % CI \u221210.94 to \u22121.24,\n P<\/jats:italic>\n =.01) and the predialysis diastolic BP (\n t<\/jats:italic>\n 163<\/jats:sub>\n =3.20,\n P<\/jats:italic>\n =.002; \u03b2=\u22124.93, 95% CI \u22127.93 to \u22121.93,\n P<\/jats:italic>\n =.001). Scores on the HBPM Knowledge Questionnaire (\n t<\/jats:italic>\n 163<\/jats:sub>\n =\u22129.18,\n P<\/jats:italic>\n <.001), HBPM Perception Scale (\n t<\/jats:italic>\n 163<\/jats:sub>\n =\u221210.65,\n P<\/jats:italic>\n <.001), and HBPM Adherence Scale (\n t<\/jats:italic>\n 163<\/jats:sub>\n =\u22128.04,\n P<\/jats:italic>\n <.001) were significantly higher after 6 months of intervention.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The implementation of a web-based HBPM program can enhance predialysis BP control and the knowledge, perception, and adherence to HBPM among patients undergoing hemodialysis. This web-based HBPM program should be promoted in appropriate clinical settings.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/53355","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T05:31:20Z","timestamp":1724823080000},"page":"e53355-e53355","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of a Web-Based Home Blood Pressure Monitoring Program in Improving Predialysis Blood Pressure Control Among Patients Undergoing Hemodialysis: Randomized Controlled Trial"],"prefix":"10.2196","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9455-7034","authenticated-orcid":false,"given":"Tingting","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5046-8300","authenticated-orcid":false,"given":"Wenbo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7422-3671","authenticated-orcid":false,"given":"Qianqian","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4229-9154","authenticated-orcid":false,"given":"Yanru","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0728-2991","authenticated-orcid":false,"given":"Jinmei","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3792-8668","authenticated-orcid":false,"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1590-7954","authenticated-orcid":false,"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7696-9991","authenticated-orcid":false,"given":"Jing","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2024,8,9]]},"reference":[{"issue":"10","key":"R1","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/s41581-020-0315-4","article-title":"The current and future landscape of dialysis","volume":"16","author":"Himmelfarb","journal-title":"Nat Rev Nephrol"},{"key":"R2","unstructured":"Tan R Kang Y Dou P Wang Y Yang Y . 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