{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T06:59:26Z","timestamp":1791442766910,"version":"4.3.3"},"reference-count":48,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>About 1.35 million deaths annually are attributed to tobacco use in India. The main challenge, given the magnitude of tobacco use and limited resources, is delivering cessation support at scale, low cost, and through a coordinated cross-system effort; one such example being brief advice interventions. However, highly credentialed staff to identify and counsel tobacco users are scarce. Task-shifting is an important opportunity for scaling these interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The LifeFirst SWASTH (Supporting Wellbeing among Adults by Stopping Tobacco Habit) program\u2014adapted from the LifeFirst program (developed by the Narotam Sekhsaria Foundation, Mumbai, India)\u2014is a tobacco cessation program focusing on lower-socioeconomic status patients in Mumbai receiving private health care. This parallel-arm, cluster randomized controlled trial investigates whether the LifeFirst SWASTH program increases tobacco cessation rates in low-resource, high-reach health care settings in Mumbai.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study will target tuberculosis-specific nongovernmental organizations (NGOs), dental clinics, and NGOs implementing general health programs serving lower-socioeconomic status patients. Intervention arm patients will receive a pamphlet explaining tobacco\u2019s harmful effects. Practitioners will be trained to deliver brief cessation advice, and interested patients will be referred to a Narotam Sekhsaria Foundation counselor for free telephone counseling for 6 months. Control arm patients will receive the same pamphlet but not brief advice or counseling. Practitioners will have a customized mobile app to facilitate intervention delivery. Practitioners will also have access to a peer network through WhatsApp. The primary outcome is a 30-day point prevalence abstinence from tobacco. Secondary outcomes for patients and practitioners relate to intervention implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study was funded in June 2020. Due to the COVID-19 pandemic, the study experienced some delays, and practitioner recruitment commenced in November 2023. As of July 2024, all practitioners have been recruited, and practitioner recruitment and training are complete. Furthermore, 36% (1687\/4688) of patients have been recruited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>It is hypothesized that those patients who participated in the LifeFirst SWASTH program will be more likely to have been abstinent from tobacco for 30 consecutive days by the end of 6 months or at least decreased their tobacco use. LifeFirst SWASTH, if found to be effective in terms of cessation outcomes and implementation, has the potential to be scaled to other settings in India and other low- and middle-income countries. The study will be conducted in low-resource settings and will reach many patients, which will increase the impact if scaled. It will use task-shifting and an app that can be tailored to different settings, also enabling scalability. Findings will build the literature for translating evidence-based interventions from high-income countries to low- and middle-income countries and from high- to low-resource settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ClinicalTrials.gov NCT05234983; https:\/\/clinicaltrials.gov\/study\/NCT05234983<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>International Registered Report Identifier (IRRID)<\/jats:title>\n                    <jats:p>DERR1-10.2196\/57236<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/57236","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T08:00:45Z","timestamp":1725350445000},"page":"e57236","source":"Crossref","is-referenced-by-count":3,"title":["Adapting and Evaluating a Brief Advice Tobacco Cessation Intervention in High-reach, Low-resource Settings in India: Protocol for a Cluster Randomized Controlled Trial"],"prefix":"10.2196","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4132-7491","authenticated-orcid":false,"given":"Sitara L","family":"Mahtani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4795-5803","authenticated-orcid":false,"given":"Kasisomayajula","family":"Viswanath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6290-2419","authenticated-orcid":false,"given":"Himanshu A","family":"Gupte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5533-9851","authenticated-orcid":false,"given":"Gauri","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0136-3229","authenticated-orcid":false,"given":"Dinesh","family":"Jagiasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7756-7921","authenticated-orcid":false,"given":"Ratandeep","family":"Chawla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4737-227X","authenticated-orcid":false,"given":"Marina","family":"D'Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6139-4785","authenticated-orcid":false,"given":"Ziming","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7811-5356","authenticated-orcid":false,"given":"Sara","family":"Minsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0650-9433","authenticated-orcid":false,"given":"Shoba","family":"Ramanadhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"ref1","unstructured":"TobaccoWorld Health Organization2024-07-25Indiahttps:\/\/www.who.int\/india\/health-topics\/tobacco#:~:text=Tobacco%20use%20is%20a%20major,1.35%20million%20deaths%20every%20year"},{"key":"ref2","unstructured":"Global adult tobacco survey. India 2016-2017 ReportMinistry of Health and Family Welfare - Government of India20172024-07-25New Delhi, Indiahttps:\/\/ntcp.nhp.gov.in\/assets\/document\/surveys-reports-publications\/Global-Adult-Tobacco-Survey-Second-Round-India-2016-2017.pdf"},{"key":"ref3","year":"2016","journal-title":"WHO FCTC Implementation Report: India, 2016"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/0019-557X.89941"},{"key":"ref5","first-page":"54","volume":"3","author":"Sujatha, S","year":"2016","journal-title":"Indian J. Med. Res. Pharm. Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.031308.100134"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00124784-199909000-00012"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2003.011585"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/2224-3151.206929"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.18332\/tpc\/156449"},{"key":"ref11","unstructured":"Global Adult Tobacco Survey (GATS) India Report: 2009-2010International Institute for Population Sciences (IIPS)20102024-07-25New Delhi, Indiahttps:\/\/ntcp.nhp.gov.in\/assets\/document\/surveys-reports-publications\/Global-Adult-Tobacco-Survey-India-2009-2010-Report.pdf"},{"key":"ref12","unstructured":"Smokeless tobacco and public health in IndiaMinistry of Health and Family Welfare - Government of India20162024-07-25New Delhihttps:\/\/ntcp.mohfw.gov.in\/assets\/document\/surveys-reports-publications\/Smokeless-Tobacco-and-Public-Health-in-India.pdf"},{"issue":"4","key":"ref13","first-page":"285","volume":"83","author":"Gericke, CA","year":"2005","journal-title":"Bull World Health Organ"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzi051"},{"key":"ref15","year":"2013","journal-title":"WHO Framework Convention on Tobacco Control: Guidelines for Implementation Article 5.3; Article 8; Articles 9 and 10; Article 11; Article 12; Article 13; Article 14"},{"key":"ref16","author":"Fiore, M","year":"2008","journal-title":"Treating Tobacco Use and Dependence: 2008 Update: Clinical Practice Guideline"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1998.0353"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-14538-2"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61888-0"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4103\/ijph.IJPH_143_16"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2011.06.012"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3402\/gha.v8.27278"},{"key":"ref23","unstructured":"BalasubramanyaBIsaacRPhilipSPrashanthHRAbrahamPPoobalanAThomasNJeyaseelanLMammenJDevarasettyPJohnOTask shifting to frontline community health workers for improved diabetes care in low-resource settings in India: a phase II non-randomized controlled clinical trialJ. Glob. Health Rep20202023-11-13https:\/\/aura.abdn.ac.uk\/bitstream\/handle\/2164\/15386\/Balasubramanya_et_al_JGHR_TaskShiftingToFrontline_VoR.pdf?sequence=1"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-010-0327-7"},{"key":"ref25","first-page":"1","author":"Fixsen, DL","year":"2005","journal-title":"University of South Florida, Louis de la Parte Florida Mental Health Institute, The National Implementation Research Network"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-014-0124-x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1097\/01.PHH.0000311891.73078.50"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/1468-0009.t01-1-00052"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-015-0272-7"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1177\/1090198115610572"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1177\/1090198115610572"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-9-237"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60783-6"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12525"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20031"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/s0828-282x(06)70294-x"},{"key":"ref37","unstructured":"AMcEwenAStandard treatment programme: one-to-one smoking cessation supportNHS Centre for Smoking Cessation and Training20112024-07-25London, Englandhttps:\/\/www.ncsct.co.uk\/library\/view\/pdf\/NCSCT%20Standard%20Treatment%20Programme.pdf"},{"key":"ref38","unstructured":"Massachusetts general hospitalTobacco Treatment Service2024-07-25http:\/\/www.massgeneral.org\/tts\/"},{"key":"ref39","unstructured":"Toolkit for delivering the 5A\u2019s and 5R\u2019s brief tobacco interventions to TB patients in primary careWorld Health Organization20142024-07-25https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/112836\/9789241506946_eng.pdf"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.5588\/pha.17.0085"},{"issue":"2","key":"ref41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/(SICI)1099-1379(199903)20:2<159::AID-JOB881>3.0.CO;2-7","volume":"20","author":"Randall, ML","year":"1999","journal-title":"J Organiz Behav"},{"key":"ref42","author":"Fiore, MC","year":"2008","journal-title":"Treating Tobacco Use and Dependence: 2008 Update: Clinical Practice Guideline"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyad064"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-017-0635-3"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000165.pub3"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1111\/add.12420"},{"key":"ref47","unstructured":"National list of essential medicines (NLEM)Ministry of Health and Family Welfare - Government of India20222024-10-25https:\/\/main.mohfw.gov.in\/newshighlights-104"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-021-01097-0"}],"container-title":["JMIR Research Protocols"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.researchprotocols.org\/2024\/1\/e57236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:47:22Z","timestamp":1782841642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.researchprotocols.org\/2024\/1\/e57236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":48,"URL":"https:\/\/doi.org\/10.2196\/57236","relation":{"has-preprint":[{"id-type":"doi","id":"10.2196\/preprints.57236","asserted-by":"object"}]},"ISSN":["1929-0748"],"issn-type":[{"value":"1929-0748","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,3]]}}}