{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:44:11Z","timestamp":1785545051603,"version":"3.56.0"},"reference-count":50,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Interact J Med Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The global targets for HIV testing for achieving the Joint United Nations Programme on HIV\/AIDS (UNAIDS) 95-95-95 targets are still short. Identifying gaps and opportunities for HIV testing uptake is crucial in fast-tracking the second (initiate people living with HIV on antiretroviral therapy) and third (viral suppression) UNAIDS goals. Machine learning and health technologies can precisely predict high-risk individuals and facilitate more effective and efficient HIV testing methods. Despite this advancement, there exists a research gap regarding the extent to which such technologies are integrated into HIV testing strategies worldwide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The study aimed to examine the characteristics, citation patterns, and contents of published studies applying machine learning and emerging health technologies in HIV testing from 2000 to 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This bibliometric analysis identified relevant studies using machine learning and emerging health technologies in HIV testing from the Web of Science database using synonymous keywords. The Bibliometrix R package was used to analyze the characteristics, citation patterns, and contents of 266 articles. The VOSviewer software was used to conduct network visualization. The analysis focused on the yearly growth rate, citation analysis, keywords, institutions, countries, authorship, and collaboration patterns. Key themes and topics were driven by the authors\u2019 most frequent keywords, which aided the content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The analysis revealed a scientific annual growth rate of 15.68%, with an international coauthorship of 8.22% and an average citation count of 17.47 per document. The most relevant sources were from high-impact journals such as the\n                      <jats:italic>Journal of Internet Medicine Research<\/jats:italic>\n                      ,\n                      <jats:italic>JMIR mHealth and uHealth<\/jats:italic>\n                      ,\n                      <jats:italic>JMIR Research Protocols<\/jats:italic>\n                      ,\n                      <jats:italic>mHealth<\/jats:italic>\n                      ,\n                      <jats:italic>AIDS Care-Psychological and Socio-Medical Aspects of AI<\/jats:italic>\n                      , and\n                      <jats:italic>BMC Public Health<\/jats:italic>\n                      , and\n                      <jats:italic>PLOS One<\/jats:italic>\n                      . The United States of America, China, South Africa, the United Kingdom, and Australia produced the highest number of contributions. Collaboration analysis showed significant networks among universities in high-income countries, including the University of North Carolina, Emory University, the University of Michigan, San Diego State University, the University of Pennsylvania, and the London School of Hygiene and Tropical Medicine. The discrepancy highlights missed opportunities in strategic partnerships between high-income and low-income countries. The results further demonstrate that machine learning and health technologies enhance the effective and efficient implementation of innovative HIV testing methods, including HIV self-testing among priority populations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study identifies trends and hotspots of machine learning and health technology research in relation to HIV testing across various countries, institutions, journals, and authors. The trends are higher in high-income countries with a greater focus on technology applications for HIV self-testing among young people and priority populations. These insights will inform future researchers about the dynamics of research outputs and help them make scholarly decisions to address research gaps in this field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/64829","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T11:35:26Z","timestamp":1747913726000},"page":"e64829-e64829","source":"Crossref","is-referenced-by-count":5,"title":["Application of Machine Learning and Emerging Health Technologies in the Uptake of HIV Testing: Bibliometric Analysis of Studies Published From 2000 to 2024"],"prefix":"10.2196","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6920-9919","authenticated-orcid":false,"given":"Musa","family":"Jaiteh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6128-2337","authenticated-orcid":false,"given":"Edith","family":"Phalane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2422-4768","authenticated-orcid":false,"given":"Yegnanew A","family":"Shiferaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8848-1149","authenticated-orcid":false,"given":"Lateef Babatunde","family":"Amusa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9811-3358","authenticated-orcid":false,"given":"Hossana","family":"Twinomurinzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9387-0432","authenticated-orcid":false,"given":"Refilwe Nancy","family":"Phaswana-Mafuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"R1","unstructured":"The global health observatory: summary of the global HIV endemic, 2022. World Health Organization. URL: https:\/\/www.who.int\/data\/gho\/data\/themes\/hiv-aids [Accessed 12-05-2025]"},{"key":"R2","unstructured":"Global HIV & AIDS statistics. UNAIDS. URL: https:\/\/www.unaids.org\/en\/resources\/fact-sheet [Accessed 12-05-2025]"},{"key":"R3","unstructured":"2025 target: putting people living with HIV and communities at risk at the centre. UNAIDS. URL: https:\/\/aidstargets2025.unaids.org [Accessed 12-05-2025]"},{"key":"R4","unstructured":"Global HIV programme: HIV testing services. World Health Organization. URL: https:\/\/www.who.int\/teams\/global-hiv-hepatitis-and-stis-programmes\/hiv\/testing-diagnostics\/hiv-testing-services [Accessed 12-05-2025]"},{"key":"R5","unstructured":"WHO recommends self-HIV testing \u2013 evidence update and considerations for success. World Health Organization. URL: https:\/\/www.who.int\/publications\/i\/item\/WHO-CDS-HIV-19.36 [Accessed 12-05-2025]"},{"issue":"4","key":"R6","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s11904-021-00565-y","article-title":"Technology-delivered intervention strategies to bolster HIV testing","volume":"18","author":"Romero","journal-title":"Curr HIV\/AIDS Rep"},{"issue":"1","key":"R7","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01346-2","article-title":"Use of machine learning techniques to identify HIV predictors for screening in sub-Saharan Africa","volume":"21","author":"Mutai","journal-title":"BMC Med Res Methodol"},{"issue":"1","key":"R8","doi-asserted-by":"publisher","first-page":"5","DOI":"10.21786\/bbrc\/11.1\/2","article-title":"Biophotonics and machine learning model for the diagnosis and treatment of HIV","volume":"11","author":"Dubey","journal-title":"Biosci Biotech Res Comm"},{"issue":"1","key":"R9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/v10010034","article-title":"Biomarkers of progression after HIV acute\/early infection: nothing compares to CD4","volume":"10","author":"Turk","journal-title":"Viruses"},{"issue":"2","key":"R10","doi-asserted-by":"publisher","first-page":"391","DOI":"10.14569\/IJACSA.2022.0130246","article-title":"Machine learning model for prediction and visualization of HIV index testing in Northern Tanzania","volume":"13","author":"Chikusi","journal-title":"IJACSA"},{"issue":"7","key":"R11","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.3390\/jcm11071818","article-title":"A machine-learning-based risk-prediction tool for HIV and sexually transmitted infections acquisition over the next 12 months","volume":"11","author":"Xu","journal-title":"J Clin Med"},{"issue":"2","key":"R12","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1007\/s10461-016-1628-y","article-title":"Factors associated with HIV testing among participants from substance use disorder treatment programs in the US: a machine learning approach","volume":"21","author":"Pan","journal-title":"AIDS Behav"},{"issue":"1","key":"R13","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-11817-2","article-title":"Effectiveness of sexual health influencers identified by an ensemble machine learning model in promoting secondary distribution of HIV self-testing among men who have sex with men in China: study protocol for a quasi-experimental trial","volume":"21","author":"Lu","journal-title":"BMC Public Health"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"van Heerden A Ntinga X Vilakazi K . The potential of conversational agents to provide a rapid HIV counseling and testing services. Presented at: 2017 International Conference on the Frontiers and Advances in Data Science (FADS); Oct 23-25, 2017; Xi\u2019an, China. [doi: 10.1109\/FADS.2017.8253198]","DOI":"10.1109\/FADS.2017.8253198"},{"issue":"7","key":"R15","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1038\/s41591-021-01384-9","article-title":"Deep learning of HIV field-based rapid tests","volume":"27","author":"Turb\u00e9","journal-title":"Nat Med"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Gupta K Ruan Y Ibrahim A et al. Transforming rapid diagnostic tests into trusted diagnostic tools in LMIC using AI. Presented at: 2023 IEEE Conference on Artificial Intelligence (CAI); Jun 5-6, 2023; Santa Clara, CA. [doi: 10.1109\/CAI54212.2023.00136]","DOI":"10.1109\/CAI54212.2023.00136"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1334881","article-title":"Measuring the performance of computer vision artificial intelligence to interpret images of HIV self-testing results","volume":"12","author":"Roche","journal-title":"Front Public Health"},{"key":"R18","unstructured":"Web of Science. 2024. URL: https:\/\/www.webofscience.com\/wos\/woscc\/basic-search"},{"issue":"2","key":"R19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/ijcs.13031","article-title":"How to conduct a bibliometric content analysis: guidelines and contributions of content co\u2010occurrence or co\u2010word literature reviews","volume":"48","author":"Klarin","journal-title":"Int J Consumer Studies"},{"issue":"March","key":"R20","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.jbusres.2021.04.070","article-title":"How to conduct a bibliometric analysis: an overview and guidelines","volume":"133","author":"Donthu","journal-title":"J Bus Res"},{"issue":"February","key":"R21","doi-asserted-by":"publisher","first-page":"1606354","DOI":"10.3389\/phrs.2024.1606354","article-title":"Digital intervention services to promote HIV self-testing and linkage to care services: a bibliometric and content analysis-global trends and future directions","volume":"45","author":"Mhando","journal-title":"Public Health Rev"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.2196\/46042","article-title":"Studies on HIV\/AIDS among students: bibliometric analysis","volume":"12","author":"Wang","journal-title":"Interact J Med Res"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.2196\/42292","article-title":"Big data and infectious disease epidemiology: bibliometric analysis and research agenda","volume":"12","author":"Amusa","journal-title":"Interact J Med Res"},{"issue":"4","key":"R24","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1016\/j.joi.2017.08.007","article-title":"bibliometrix: an R-tool for comprehensive science mapping analysis","volume":"11","author":"Aria","journal-title":"J Informetr"},{"issue":"2","key":"R25","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1002\/joe.22229","article-title":"Guidelines for interpreting the results of bibliometric analysis: a sensemaking approach","volume":"43","author":"Lim","journal-title":"Glob Bus Org Exc"},{"issue":"3","key":"R26","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1007\/s11192-010-0193-9","article-title":"An index to quantify an individual\u2019s scientific research output that takes into account the effect of multiple coauthorship","volume":"85","author":"Hirsch","journal-title":"Scientometrics"},{"issue":"5","key":"R27","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.3393","article-title":"eHealth interventions for HIV prevention in high-risk men who have sex with men: a systematic review","volume":"16","author":"Schnall","journal-title":"J Med Internet Res"},{"issue":"1","key":"R28","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s11904-014-0239-3","article-title":"A systematic review of recent smartphone, Internet and Web 2.0 interventions to address the HIV continuum of care","volume":"12","author":"Muessig","journal-title":"Curr HIV\/AIDS Rep"},{"key":"R29","unstructured":"Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. World Health Organization. URL: http:\/\/apps.who.int\/iris\/bitstream\/10665\/128048\/1\/9789241507431_eng.pdf?ua=1 [Accessed 12-05-2025]"},{"issue":"8","key":"R30","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1007\/s11121-021-01255-2","article-title":"Using machine learning to predict young people\u2019s internet health and social service information seeking","volume":"22","author":"Comulada","journal-title":"Prev Sci"},{"issue":"9","key":"R31","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed7090231","article-title":"Predicting HIV status among men who have sex with men in Bulawayo & Harare, Zimbabwe using bio-behavioural data, recurrent neural networks, and machine learning techniques","volume":"7","author":"Chingombe","journal-title":"Trop Med Infect Dis"},{"issue":"10","key":"R32","doi-asserted-by":"publisher","DOI":"10.2196\/42055","article-title":"Formative evaluation of the acceptance of HIV prevention artificial intelligence chatbots by men who have sex with men in Malaysia: focus group study","volume":"6","author":"Peng","journal-title":"JMIR Form Res"},{"issue":"3","key":"R33","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1111\/1467-9566.13242","article-title":"'You\u2019re only there on the phone'? A qualitative exploration of community, affect and agential capacity in HIV self-testing using a smartphone app","volume":"43","author":"Janssen","journal-title":"Sociol Health Illn"},{"issue":"9","key":"R34","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1097\/OLQ.0b013e3181a9cc41","article-title":"Prediction of HIV acquisition among men who have sex with men","volume":"36","author":"Menza","journal-title":"Sex Transm Dis"},{"issue":"1","key":"R35","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-6046-9","article-title":"MHealth approach to promote oral HIV self-testing among men who have sex with men in China: a qualitative description","volume":"18","author":"Zhao","journal-title":"BMC Public Health"},{"issue":"3","key":"R36","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1111\/add.16379","article-title":"Network centrality and HIV prevention service use among people who inject drugs: findings from a sociometric network cohort in New Delhi, India","volume":"119","author":"Prata Menezes","journal-title":"Addiction"},{"issue":"Suppl 1","key":"R37","doi-asserted-by":"publisher","first-page":"S75","DOI":"10.1097\/QAD.0000000000002867","article-title":"Adolescent HIV-related behavioural prediction using machine learning: a foundation for precision HIV prevention","volume":"35","author":"Wang","journal-title":"AIDS"},{"key":"R38","unstructured":"HOME-BASED HIV SELF-TESTING WITH ONLINE INSTRUCTION AND COUNSELING (HIVST-OIC). Centers for Disease Control and Prevention. URL: https:\/\/stacks.cdc.gov\/view\/cdc\/149596 [Accessed 12-05-2025]"},{"issue":"12","key":"R39","doi-asserted-by":"publisher","DOI":"10.2196\/39816","article-title":"The feasibility and acceptability of an mHealth conversational agent designed to support HIV self-testing in South Africa: cross-sectional study","volume":"24","author":"Ntinga","journal-title":"J Med Internet Res"},{"issue":"10","key":"R40","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.26185","article-title":"Findings from the Tushirikiane mobile health (mHealth) HIV self-testing pragmatic trial with refugee adolescents and youth living in informal settlements in Kampala, Uganda","volume":"26","author":"Logie","journal-title":"J Int AIDS Soc"},{"issue":"1","key":"R41","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-021-07259-6","article-title":"Venues and methods to improve professional men\u2019s access to HIV self-testing and linkage to HIV prevention or treatment: a qualitative study","volume":"21","author":"Muwanguzi","journal-title":"BMC Health Serv Res"},{"issue":"1","key":"R42","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1097\/QCO.0000000000000426","article-title":"Scaling up HIV self-testing in sub-Saharan Africa: a review of technology, policy and evidence","volume":"31","author":"Indravudh","journal-title":"Curr Opin Infect Dis"},{"issue":"1","key":"R43","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/s41591-018-0300-7","article-title":"High-performance medicine: the convergence of human and artificial intelligence","volume":"25","author":"Topol","journal-title":"Nat Med"},{"issue":"1","key":"R44","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1097\/SLA.0000000000002693","article-title":"Artificial intelligence in surgery: promises and perils","volume":"268","author":"Hashimoto","journal-title":"Ann Surg"},{"issue":"1","key":"R45","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1038\/s41591-018-0316-z","article-title":"A guide to deep learning in healthcare","volume":"25","author":"Esteva","journal-title":"Nat Med"},{"issue":"7","key":"R46","doi-asserted-by":"publisher","DOI":"10.2196\/18228","article-title":"Artificial intelligence in health care: bibliometric analysis","volume":"22","author":"Guo","journal-title":"J Med Internet Res"},{"issue":"6","key":"R47","doi-asserted-by":"publisher","DOI":"10.1098\/rsfs.2021.0025","article-title":"How COVID-19 has changed medical research funding","volume":"11","author":"Chinnery","journal-title":"Interface Focus"},{"issue":"July","key":"R48","doi-asserted-by":"publisher","first-page":"104558","DOI":"10.1016\/j.ijmedinf.2021.104558","article-title":"Emergence and evolution of big data science in HIV research: bibliometric analysis of federally sponsored studies 2000-2019","volume":"154","author":"Liang","journal-title":"Int J Med Inform"},{"issue":"3","key":"R49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017428","article-title":"Evaluating research and impact: a bibliometric analysis of research by the NIH\/NIAID HIV\/AIDS clinical trials networks","volume":"6","author":"Rosas","journal-title":"PLOS One"},{"issue":"8","key":"R50","doi-asserted-by":"publisher","DOI":"10.3390\/a17080362","article-title":"Utilization of machine learning algorithms for the strengthening of HIV testing: a systematic review","volume":"17","author":"Jaiteh","journal-title":"Algorithms"}],"container-title":["Interactive Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.i-jmr.org\/2025\/1\/e64829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:30:09Z","timestamp":1785537009000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.i-jmr.org\/2025\/1\/e64829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,22]]},"references-count":50,"URL":"https:\/\/doi.org\/10.2196\/64829","relation":{},"ISSN":["1929-073X"],"issn-type":[{"value":"1929-073X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,22]]},"article-number":"v14i4e64829"}}