{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:55:50Z","timestamp":1790272550390,"version":"4.1.0"},"reference-count":77,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Cancer"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Survivors with head and neck cancer (HNC) face challenging treatment consequences that can lead to severe disruptions in swallowing and result in weight loss, malnutrition, and feeding tube dependence. Caregivers (family or friends who provide support), therefore, often encounter distressing nutritional caregiving burdens and feel unprepared to provide adequate support at home.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The purpose of this mixed methods study was to develop a mobile support app to support HNC caregiving with an emphasis on nutritional support following treatment.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We assessed perspectives on nutritional recovery challenges and mobile support app preferences in (1) a national panel of oncology dietitians using a web-based cross-sectional survey and (2) survivors with HNC completing treatment within the past 24 months and their nominated caregivers using dyadic semistructured interviews. Descriptive statistics for survey data were synthesized with thematic analysis of interview data to characterize nutrition-related perceptions and intervention preferences; results were integrated, and themes were translated to high-priority main menu domains and subdomains for a mobile app for caregivers.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Surveys were completed by dietitians (n=116, 100%; female n=87, 50%, with >10 years practice experience). Interviews included survivors with HNC (n=15; 12\/15, 80% male, and 6\/15, 40% with oropharynx cancer) and their caregivers (n=13; 11\/13, 85% female, and 10\/13, 77% spouses). Dietitians, survivors, and caregivers perceived that the majority of nutritional concerns assessed (eg, swallowing, feeding tube management, weight maintenance, and caregiver distress about nutrition) were very or extremely important to caregiving in the 6 months following treatment conclusion. The caregiving tasks rated highest in importance by dietitians included tracking nutritional concerns (n=113, 97%), working together as a team on nutritional concerns (n=104, 90%), and making care decisions (n=102, 88%). Five themes emerged from dyadic interviews, including types of nutritional challenges faced, that competing symptoms were difficult to separate from nutritional challenges, the emotional challenges related to nutrition and recovery, the diverse set of medical and support tasks taken on by caregivers, and information and resource needs in caregivers. Qualitative interview and survey themes guided the content of the Healthy Eating and Recovery Together (HEART) app with an intake tracker and sections for nutrition recovery support, other competing caregiving tips, peer support, and caregiver self-care.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Results pinpointed optimal content for a mobile app for caregivers of individuals with HNC and support the acceptability of implementing the HEART app following HNC treatment.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/66471","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T09:14:01Z","timestamp":1749633241000},"page":"e66471-e66471","source":"Crossref","is-referenced-by-count":3,"title":["Development of a Mobile App to Support Head and Neck Cancer Caregiving: Mixed Methods Study"],"prefix":"10.2196","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9780-8695","authenticated-orcid":false,"given":"Katherine","family":"Sterba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-468X","authenticated-orcid":false,"given":"Evan","family":"Graboyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9170-0701","authenticated-orcid":false,"given":"Jessica","family":"Burris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0614-4098","authenticated-orcid":false,"given":"Megan","family":"Scallion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9121-6665","authenticated-orcid":false,"given":"Hannah","family":"Kinder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8690-9527","authenticated-orcid":false,"given":"Jama","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7978-8416","authenticated-orcid":false,"given":"Benjamin","family":"Toll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3758-6693","authenticated-orcid":false,"given":"Kent","family":"Armeson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1431-4214","authenticated-orcid":false,"given":"Terry","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2816-3557","authenticated-orcid":false,"given":"Bhishamjit","family":"Chera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8504-6988","authenticated-orcid":false,"given":"Kenneth","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"R1","unstructured":"Cancer stat factors: oral cavity and pharynx cancer. National Cancer Institute Surveillance, Epidemiology and End Results Program. 2021. URL: http:\/\/seer.cancer.gov\/statfacts\/html\/oralcav.html [Accessed 13-09-2024]"},{"key":"R2","unstructured":"Cancer stat factors: larynx cancer. National Cancer Institute Surveillance, Epidemiology and End Results Program. URL: http:\/\/seer.cancer.gov\/statfacts\/html\/laryn.html [Accessed 13-09-2024]"},{"issue":"3","key":"R3","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3322\/caac.21343","article-title":"American Cancer Society head and neck cancer survivorship care guideline","volume":"66","author":"Cohen","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"R4","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/lio2.702","article-title":"Head and neck cancer survivorship consensus statement from the American Head and Neck Society","volume":"7","author":"Goyal","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"4","key":"R5","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1002\/ohn.302","article-title":"Expert consensus statement: management of dysphagia in head and neck cancer patients","volume":"168","author":"Kuhn","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R6","unstructured":"National Comprehensive Cancer Network practice guidelines in oncology: head and neck cancers. NCCN. URL: http:\/\/www.nccn.org\/professionals\/physician_gls\/PDF\/head-and-neck.pdf [Accessed 02-01-2024]"},{"issue":"8","key":"R7","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1007\/s00520-010-0827-8","article-title":"A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life","volume":"18","author":"Jensen","journal-title":"Support Care Cancer"},{"issue":"9","key":"R8","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s00520-006-0212-9","article-title":"Critical weight loss in head and neck cancer\u2014prevalence and risk factors at diagnosis: an explorative study","volume":"15","author":"Jager-Wittenaar","journal-title":"Support Care Cancer"},{"issue":"1","key":"R9","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1136\/bmjspcare-2019-002077","article-title":"Nutrition impact symptoms and weight loss in head and neck cancer during radiotherapy: a longitudinal study","volume":"11","author":"Jin","journal-title":"BMJ Support Palliat Care"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.10.021","article-title":"Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo)radiotherapy","volume":"52","author":"Langius","journal-title":"Oral Oncol"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2021.105522","article-title":"Weight loss and its impact on outcome in head and cancer patients during chemo-radiation","volume":"122","author":"Singh","journal-title":"Oral Oncol"},{"issue":"2","key":"R12","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1002\/hed.25412","article-title":"Two-year prevalence of dysphagia and related outcomes in head and neck cancer survivors: an updated SEER-Medicare analysis","volume":"41","author":"Hutcheson","journal-title":"Head Neck"},{"issue":"11","key":"R13","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1007\/s00520-014-2281-5","article-title":"Oral health-related quality of life and malnutrition in patients treated for oral cancer","volume":"22","author":"Barrios","journal-title":"Support Care Cancer"},{"issue":"5","key":"R14","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1007\/s00520-017-3618-7","article-title":"The life experience of nutrition impact symptoms during treatment for head and neck cancer patients: a systematic review and meta-synthesis","volume":"25","author":"Bressan","journal-title":"Support Care Cancer"},{"issue":"4","key":"R15","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s11764-018-0687-7","article-title":"Nutrition impact symptoms and associated outcomes in post-chemoradiotherapy head and neck cancer survivors: a systematic review","volume":"12","author":"Crowder","journal-title":"J Cancer Surviv"},{"issue":"1","key":"R16","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1080\/01635581.2013.741749","article-title":"More than 10% weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life","volume":"65","author":"Langius","journal-title":"Nutr Cancer"},{"issue":"8","key":"R17","doi-asserted-by":"publisher","first-page":"979","DOI":"10.2217\/fon-2020-0881","article-title":"Oral health-related quality of life in oral cancer patients: systematic review and meta-analysis","volume":"17","author":"Yuwanati","journal-title":"Future Oncol"},{"issue":"5","key":"R18","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1111\/j.1365-277X.2011.01165.x","article-title":"Different experiences and perspectives between head and neck cancer patients and their care-givers on their daily impact of a gastrostomy tube","volume":"24","author":"Mayre-Chilton","journal-title":"J Hum Nutr Diet"},{"issue":"4","key":"R19","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.jpainsymman.2011.10.016","article-title":"Family members\u2019 experiences caring for patients with advanced head and neck cancer receiving tube feeding: a descriptive phenomenological study","volume":"44","author":"Penner","journal-title":"J Pain Symptom Manage"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2016.08.004","article-title":"Development of the head and neck cancer caregiving task inventory","volume":"24","author":"Bond","journal-title":"Eur J Oncol Nurs"},{"issue":"3","key":"R21","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1002\/pon.4968","article-title":"Impact of patient symptoms and caregiving tasks on psychological distress in caregivers for head and neck cancer (HNC)","volume":"28","author":"Castellanos","journal-title":"Psychooncology"},{"issue":"6","key":"R22","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1080\/07347332.2017.1323817","article-title":"Physical and emotional well-being and support in newly diagnosed head and neck cancer patient-caregiver dyads","volume":"35","author":"Sterba","journal-title":"J Psychosoc Oncol"},{"issue":"5","key":"R23","doi-asserted-by":"publisher","first-page":"462","DOI":"10.3109\/09638288.2015.1046563","article-title":"Third-party disability in carers of people with dysphagia following non-surgical management for head and neck cancer","volume":"38","author":"Nund","journal-title":"Disabil Rehabil"},{"issue":"4","key":"R24","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1007\/s00455-014-9527-8","article-title":"Carers\u2019 experiences of dysphagia in people treated for head and neck cancer: a qualitative study","volume":"29","author":"Nund","journal-title":"Dysphagia"},{"issue":"11","key":"R25","doi-asserted-by":"publisher","first-page":"9359","DOI":"10.1007\/s00520-022-07348-0","article-title":"A qualitative comparison of the nutrition care experiences of carers supporting patients with head and neck cancer throughout surgery and radiation treatment and survivorship","volume":"30","author":"Hiatt","journal-title":"Support Care Cancer"},{"issue":"1","key":"R26","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1007\/s00520-021-06484-3","article-title":"Patient and carer experience of nutrition care throughout and beyond treatment for head and neck cancer: a qualitative longitudinal study","volume":"30","author":"Hiatt","journal-title":"Support Care Cancer"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2017.06.011","article-title":"Partner\u2019s survivorship care needs: an analysis in head and neck cancer patients","volume":"71","author":"Giuliani","journal-title":"Oral Oncol"},{"issue":"11-12","key":"R28","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1111\/jocn.13140","article-title":"The unmet supportive care needs of long-term head and neck cancer caregivers in the extended survivorship period","volume":"25","author":"Balfe","journal-title":"J Clin Nurs"},{"issue":"5","key":"R29","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-023-07670-1","article-title":"Unmet supportive care needs among informal caregivers of patients with head and neck cancer in the first 2 years after diagnosis and treatment: a prospective cohort study","volume":"31","author":"van Hof","journal-title":"Support Care Cancer"},{"issue":"8","key":"R30","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1093\/jnci\/djad075","article-title":"Interventions to improve outcomes for caregivers of patients with advanced cancer: a meta-analysis","volume":"115","author":"Chow","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"R31","doi-asserted-by":"publisher","first-page":"318","DOI":"10.3322\/caac.21396","article-title":"A review of family caregiving intervention trials in oncology","volume":"67","author":"Ferrell","journal-title":"CA Cancer J Clin"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2022.102237","article-title":"The efficacy of psychosocial interventions for cancer caregiver burden: a systematic review and meta-analysis of randomized controlled trials","volume":"99","author":"Secinti","journal-title":"Clin Psychol Rev"},{"issue":"4","key":"R33","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1002\/pon.5018","article-title":"A systematic review of cancer caregiver interventions: appraising the potential for implementation of evidence into practice","volume":"28","author":"Ugalde","journal-title":"Psychooncology"},{"issue":"3","key":"R34","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1007\/s00520-024-08349-x","article-title":"Experiences of financial toxicity among caregivers of cancer patients: a meta-synthesis of qualitative studies","volume":"32","author":"Shi","journal-title":"Support Care Cancer"},{"issue":"5","key":"R35","doi-asserted-by":"publisher","first-page":"e622","DOI":"10.1111\/hsc.12808","article-title":"The direct and indirect financial costs of informal cancer care: a scoping review","volume":"27","author":"Coumoundouros","journal-title":"Health Soc Care Community"},{"issue":"6","key":"R36","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1007\/s13187-021-02001-6","article-title":"Care for the cancer caregiver: a qualitative study of facilitators and barriers to caregiver integration and support","volume":"37","author":"Reblin","journal-title":"J Cancer Educ"},{"issue":"6","key":"R37","doi-asserted-by":"publisher","first-page":"3793","DOI":"10.3390\/curroncol29060304","article-title":"Screening for distress and health outcomes in head and neck cancer","volume":"29","author":"Gascon","journal-title":"Curr Oncol"},{"issue":"11","key":"R38","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1002\/pon.6045","article-title":"Depression among caregivers of cancer patients: updated systematic review and meta-analysis","volume":"31","author":"Bedaso","journal-title":"Psychooncology"},{"issue":"13","key":"R39","doi-asserted-by":"publisher","first-page":"1987","DOI":"10.1002\/cncr.29939","article-title":"Caring for caregivers and patients: research and clinical priorities for informal cancer caregiving","volume":"122","author":"Kent","journal-title":"Cancer"},{"issue":"3","key":"R40","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1080\/10810730.2014.965369","article-title":"Psychosocial interventions for patients and caregivers in the age of new communication technologies: opportunities and challenges in cancer care","volume":"20","author":"Badr","journal-title":"J Health Commun"},{"issue":"10","key":"R41","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1037\/a0034216","article-title":"CHESS improves cancer caregivers\u2019 burden and mood: results of an eHealth RCT","volume":"33","author":"DuBenske","journal-title":"Health Psychol"},{"issue":"6","key":"R42","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1177\/0272989X10386382","article-title":"Web-based cancer communication and decision making systems: connecting patients, caregivers, and clinicians for improved health outcomes","volume":"30","author":"DuBenske","journal-title":"Med Decis Making"},{"issue":"1","key":"R43","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4160-9","article-title":"Feasibility, useability and acceptability of technology-based interventions for informal cancer carers: a systematic review","volume":"18","author":"Heynsbergh","journal-title":"BMC Cancer"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_201397","article-title":"Supporting caregivers of patients with cancer: a summary of technology-mediated interventions and future directions","volume":"38","author":"Shin","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"R45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2015.12.013","article-title":"Effects of eHealth for patients and informal caregivers confronted with cancer: a meta-review","volume":"87","author":"Slev","journal-title":"Int J Med Inform"},{"key":"R46","unstructured":"Creswell JW Clark VLP . Designing and Conducting Mixed Methods Research. 3rd ed. SAGE; 2018."},{"issue":"6 Pt 2","key":"R47","doi-asserted-by":"publisher","first-page":"2134","DOI":"10.1111\/1475-6773.12117","article-title":"Achieving integration in mixed methods designs-principles and practices","volume":"48","author":"Fetters","journal-title":"Health Serv Res"},{"issue":"2","key":"R48","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1258\/jhsrp.2007.007074","article-title":"The quality of mixed methods studies in health services research","volume":"13","author":"O\u2019Cathain","journal-title":"J Health Serv Res Policy"},{"issue":"3","key":"R49","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1097\/00012272-200607000-00009","article-title":"A transactional model of cancer family caregiving skill","volume":"29","author":"Schumacher","journal-title":"ANS Adv Nurs Sci"},{"issue":"1","key":"R50","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.3422","article-title":"Mobile App Rating Scale: a new tool for assessing the quality of health mobile apps","volume":"3","author":"Stoyanov","journal-title":"JMIR mHealth uHealth"},{"issue":"4","key":"R51","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1007\/s11135-017-0574-8","article-title":"Saturation in qualitative research: exploring its conceptualization and operationalization","volume":"52","author":"Saunders","journal-title":"Qual Quant"},{"issue":"4","key":"R52","first-page":"565","volume":"11","author":"Ferrell","journal-title":"Oncology (Williston Park)"},{"key":"R53","unstructured":"The R project for statistical computing. R-project. URL: https:\/\/www.R-project.org [Accessed 01-04-2025]"},{"key":"R54","unstructured":"Corbin J Strauss A . Basics of Qualitative Research: Grounded Theory Procedures and Techniques. Sage; 1990."},{"key":"R55","unstructured":"NVivo qualitative data analysis software. Lumivero. URL: https:\/\/lumivero.com\/products\/nvivo\/ [Accessed 20-05-2025]"},{"issue":"6","key":"R56","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1370\/afm.1865","article-title":"Integrating quantitative and qualitative results in health science mixed methods research through joint displays","volume":"13","author":"Guetterman","journal-title":"Ann Fam Med"},{"issue":"1","key":"R57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/1609406917733847","article-title":"Thematic analysis: striving to meet the trustworthiness criteria","volume":"16","author":"Nowell","journal-title":"Int J Qual Methods"},{"key":"R58","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-018-0053-1","article-title":"Agile research to complement agile development: a proposal for an mHealth research lifecycle","volume":"1","author":"Wilson","journal-title":"NPJ Digital Med"},{"issue":"7","key":"R59","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/hed.24411","article-title":"Prevalence and nature of survivorship needs in patients with head and neck cancer","volume":"38","author":"Giuliani","journal-title":"Head Neck"},{"issue":"10","key":"R60","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1001\/jamaoto.2016.1615","article-title":"Survivorship in head and neck cancer: a primer","volume":"142","author":"Miller","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"29","key":"R61","doi-asserted-by":"publisher","first-page":"3314","DOI":"10.1200\/JCO.2015.61.3836","article-title":"Advances in supportive care for late effects of head and neck cancer","volume":"33","author":"Murphy","journal-title":"J Clin Oncol"},{"issue":"3","key":"R62","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1377\/hlthaff.2018.05067","article-title":"Patient engagement in research: early findings from the patient-centered outcomes research institute","volume":"38","author":"Forsythe","journal-title":"Health Aff (Millwood)"},{"issue":"5","key":"R63","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1007\/s11136-014-0893-3","article-title":"Conceptual and practical foundations of patient engagement in research at the patient-centered outcomes research institute","volume":"24","author":"Frank","journal-title":"Qual Life Res"},{"issue":"Suppl 1","key":"R64","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s11606-021-07104-w","article-title":"Understanding the influence and impact of stakeholder engagement in patient-centered outcomes research: a qualitative study","volume":"37","author":"Maurer","journal-title":"J Gen Intern Med"},{"key":"R65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022.104179","article-title":"The effectiveness of e-Health interventions on caregiver burden, depression, and quality of life in informal caregivers of patients with cancer: a systematic review and meta-analysis of randomized controlled trials","volume":"127","author":"Li","journal-title":"Int J Nurs Stud"},{"key":"R66","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2019.104003","article-title":"Effectiveness of health web-based and mobile app-based interventions designed to improve informal caregiver\u2019s well-being and quality of life: a systematic review","volume":"134","author":"Lorca-Cabrera","journal-title":"Int J Med Inform"},{"key":"R67","doi-asserted-by":"crossref","unstructured":"Revenson TA Kayser K Bodenmann G . Couples Coping with Stress: Emerging Perspectives on Dyadic Coping. American Psychological Association; 2005.","DOI":"10.1037\/11031-000"},{"issue":"1","key":"R68","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1111\/bjhp.12094","article-title":"Dyadic coping and relationship functioning in couples coping with cancer: a systematic review","volume":"20","author":"Traa","journal-title":"Br J Health Psychol"},{"issue":"19","key":"R69","doi-asserted-by":"publisher","first-page":"4423","DOI":"10.1002\/cncr.33100","article-title":"MASCC\/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy","volume":"126","author":"Elad","journal-title":"Cancer"},{"issue":"53","key":"R70","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgz011","article-title":"Oral mucositis due to high-dose chemotherapy and\/or head and neck radiation therapy","volume":"2019","author":"Lalla","journal-title":"J Natl Cancer Inst Monogr"},{"issue":"1","key":"R71","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6221","article-title":"Developing a national implementation strategy to accelerate uptake of evidence-based family caregiver support in U.S. cancer centers","volume":"33","author":"Odom","journal-title":"Psychooncology"},{"issue":"2","key":"R72","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1093\/jnci\/djad198","article-title":"Processes for identifying caregivers and screening for caregiver and patient distress in community oncology: results from WF-1803CD","volume":"116","author":"Nightingale","journal-title":"J Natl Cancer Inst"},{"issue":"10","key":"R73","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.37250","article-title":"Availability of family caregiver programs in US cancer centers","volume":"6","author":"Odom","journal-title":"JAMA Netw Open"},{"issue":"5 Suppl 2","key":"R74","doi-asserted-by":"publisher","first-page":"S198","DOI":"10.1016\/j.amepre.2011.01.014","article-title":"Improving modern cancer care through information technology","volume":"40","author":"Clauser","journal-title":"Am J Prev Med"},{"issue":"3","key":"R75","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pdig.0000173","article-title":"A novel smartphone application for the informal caregivers of cancer patients: usability study","volume":"2","author":"Oakley-Girvan","journal-title":"PLOS Digital Health"},{"issue":"1","key":"R76","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-53373-w","article-title":"Mobile app activity engagement by cancer patients and their caregivers informs remote monitoring","volume":"14","author":"Yunis","journal-title":"Sci Rep"},{"key":"R77","doi-asserted-by":"publisher","DOI":"10.2196\/62790","article-title":"Evolutionary trends in the adoption, adaptation, and abandonment of mobile health technologies: viewpoint based on 25 Years of research","volume":"26","author":"Portz","journal-title":"J Med Internet Res"}],"container-title":["JMIR Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cancer.jmir.org\/2025\/1\/e66471","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:28:47Z","timestamp":1785536927000},"score":1,"resource":{"primary":{"URL":"https:\/\/cancer.jmir.org\/2025\/1\/e66471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,10]]},"references-count":77,"URL":"https:\/\/doi.org\/10.2196\/66471","relation":{},"ISSN":["2369-1999"],"issn-type":[{"value":"2369-1999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,10]]},"article-number":"v11i3e66471"}}