{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:44:39Z","timestamp":1785545079704,"version":"3.56.0"},"reference-count":10,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Dermatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The VISIA camera is a device that captures images of the skin, offering a detailed look at skin health by detecting changes that are often missed during physical exams and by the naked eye. It can help identify changes in UV damage, pigmentation, texture, fine lines, and redness. In dermatology, it has become a useful tool to build targeted treatment plans and follow patient progress over time. We present a case of a male patient diagnosed with diffuse scalp actinic keratoses who was treated with topical 5-fluorouracil (5-FU). VISIA images were taken before treatment, at one week, and again three months following therapy. The images were reviewed for changes in UV spots, texture, and other generalized spots. Results revealed a decrease in UV spots, a temporary improvement in texture followed by a later rise, and no significant change in generalized spots. This case highlights the value of VISIA imaging as an objective method for assessing treatment response and evaluating the effectiveness of 5-FU in the management of actinic keratoses.<\/jats:p>","DOI":"10.2196\/66553","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T10:50:05Z","timestamp":1757933405000},"page":"e66553-e66553","source":"Crossref","is-referenced-by-count":1,"title":["Utilizing the VISIA Camera for Analyzing 5-Fluorouracil Treatment Efficacy for Actinic Keratosis"],"prefix":"10.2196","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2631-5551","authenticated-orcid":false,"given":"Emily","family":"Woolhiser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2034-5323","authenticated-orcid":false,"given":"Leena","family":"Jamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4250-4816","authenticated-orcid":false,"given":"Jessica","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0125-5094","authenticated-orcid":false,"given":"Bertha","family":"Baum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8132-088X","authenticated-orcid":false,"given":"Robert","family":"Dellavalle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"R1","unstructured":"VISIA complexion analysis. Canfield Scientific. URL: https:\/\/www.canfieldsci.com\/imaging-systems\/visia-complexion-analysis [Accessed 29-08-2025]"},{"issue":"8","key":"R2","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1038\/jid.2013.134","article-title":"Prevalence of actinic keratosis and its risk factors in the general population: the Rotterdam Study","volume":"133","author":"Flohil","journal-title":"J Invest Dermatol"},{"key":"R3","unstructured":"Marques E . Actinic Keratosis. StatPearls; 2023. URL: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557401 [Accessed 08-12-2025]"},{"issue":"10","key":"R4","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1056\/NEJMoa1811850","article-title":"Randomized trial of four treatment approaches for actinic keratosis","volume":"380","author":"Jansen","journal-title":"N Engl J Med"},{"key":"R5","unstructured":"Casale J . Fluorouracil. StatPearls; 2024. URL: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549808 [Accessed 08-12-2025]"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.3205\/iprs000169","article-title":"Investigation of the precision of the Visia complexion analysis camera system in the assessment of skin surface features","volume":"11","author":"Henseler","journal-title":"GMS Interdiscip Plast Reconstr Surg DGPW"},{"issue":"3","key":"R7","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.350","article-title":"An evaluation of the course of facial sunscreen coverage and sustainability over an 8-hour workday among outdoor workers","volume":"4","author":"Kobwanthanakun","journal-title":"Health Sci Rep"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.3205\/iprs000179","article-title":"Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia Complexion Analysis camera system for objective skin analysis","volume":"12","author":"Henseler","journal-title":"GMS Interdiscip Plast Reconstr Surg DGPW"},{"issue":"3","key":"R9","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.28.3.035001","article-title":"Deep learning-based optical approach for skin analysis of melanin and hemoglobin distribution","volume":"28","author":"Jung","journal-title":"J Biomed Opt"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.2196\/39988","article-title":"Refusal of retreatment with topical 5-fluorouracil among patients with actinic keratosis: qualitative analysis","volume":"6","author":"Singh","journal-title":"JMIR Dermatol"}],"container-title":["JMIR Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/derma.jmir.org\/2025\/1\/e66553","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:28:41Z","timestamp":1785536921000},"score":1,"resource":{"primary":{"URL":"https:\/\/derma.jmir.org\/2025\/1\/e66553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":10,"URL":"https:\/\/doi.org\/10.2196\/66553","relation":{},"ISSN":["2562-0959"],"issn-type":[{"value":"2562-0959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,19]]},"article-number":"v8i8e66553"}}