{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T22:49:26Z","timestamp":1788648566580,"version":"build-2803163510"},"reference-count":35,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Smoking is a leading cause of preventable death, and people with HIV have higher smoking rates and are more likely to experience smoking-related health issues. The Sense2Quit study introduces innovative advancements in smoking cessation technology by developing a comprehensive mobile app that integrates with smartwatches to provide real-time interventions for people with HIV attempting to quit smoking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aim to develop an accurate smoking cessation app that uses everyday smartwatches and an artificial intelligence model to enhance the recognition of smoking gestures by effectively addressing confounding hand gestures that mimic smoking, thereby reducing false positives. The app ensures seamless usability across Android (Open Handset Alliance [led by Google]) and iOS platforms, with optimized communication and synchronization between devices for real-time monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study introduces the confounding resilient smoking model, specifically trained to distinguish smoking gestures from similar hand-to-mouth activities used by the Sense2Quit system. By incorporating confounding gestures into the model\u2019s training process, the system achieves high accuracy while maintaining efficiency on mobile devices. To validate the model, 30 participants, all people with HIV who smoked cigarettes, were recruited. Participants wore smartwatches on their wrists and performed various hand-to-mouth activities, including smoking and other gestures such as eating and drinking. Each participant spent 15 to 30 minutes completing the tasks, with each gesture lasting 5 seconds. The app was developed using the Flutter framework to ensure seamless functionality across Android and iOS platforms, with robust synchronization between the smartwatch and smartphone for real-time monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The confounding resilient smoking model achieved an impressive F1-score of 97.52% in detecting smoking gestures, outperforming state-of-the-art models by distinguishing smoking from 15 other daily hand-to-mouth activities, including eating, drinking, and yawning. Its robustness and adaptability were further confirmed through leave-one-subject-out evaluation, demonstrating consistent reliability and generalizability across diverse individuals. The cross-platform app, developed using Flutter (Google), demonstrated consistent performance across Android and iOS devices, with only a 0.02-point difference in user experience ratings between the platforms (iOS 4.52 and Android 4.5). The app\u2019s continuous synchronization ensures accurate, real-time tracking of smoking behaviors, enhancing the system\u2019s overall utility for smoking cessation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sense2Quit represents a significant advancement in smoking cessation technology. It delivers timely, just-in-time interventions through innovations in cross-platform communication optimization and the effective recognition of confounding hand gestures. These improvements enhance the accuracy and accessibility of real-time smoking detection, making Sense2Quit a valuable tool for supporting long-term cessation efforts among people with HIV trying to quit smoking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>International Registered Report Identifier (IRRID)<\/jats:title>\n                    <jats:p>RR2-10.2196\/49558<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/67186","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T03:55:10Z","timestamp":1742270110000},"page":"e67186","source":"Crossref","is-referenced-by-count":4,"title":["A Robust Cross-Platform Solution With the Sense2Quit System to Enhance Smoking Gesture Recognition: Model Development and Validation 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