{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:44:27Z","timestamp":1785545067781,"version":"3.56.0"},"reference-count":28,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Perioper Med"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Measuring the optic nerve sheath diameter (ONSD) with ultrasound is a promising, noninvasive way to estimate intracranial pressure (ICP). While magnetic resonance imaging (MRI) provides high-resolution imaging, it is less accessible in urgent or perioperative settings. Comparing ONSD measurements between ultrasound and MRI may help confirm the use of ultrasound in neurosurgical patients.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The aim of this study is to evaluate how closely ultrasound and MRI measurements of ONSD align in patients undergoing surgery for supratentorial brain tumors.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This prospective, single-center observational study included 50 adult patients scheduled for elective supratentorial tumor resection. ONSD was measured preoperatively using both transorbital ultrasound and MRI. Measurements were compared using Pearson and Spearman correlation coefficients, the intraclass correlation coefficient, and Bland-Altman analysis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The average ONSD measured by ultrasound was 5.94 (0.99) mm, compared to 5.75 (SD 1.08) mm via MRI. The two methods showed a strong correlation (Pearson\n r<\/jats:italic>\n =0.88,\n P<\/jats:italic>\n <.001) and good agreement (intraclass correlation coefficient=0.86). Bland-Altman analysis showed a mean bias of 0.19 mm (95% limits of agreement: \u20130.62 to 1.00 mm).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Ultrasound-based ONSD measurements closely matched those obtained by MRI in this patient group. These findings support the use of ultrasound as a practical tool for noninvasive ICP assessment in the perioperative care of patients with intracranial tumors.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/67480","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:00:07Z","timestamp":1768874407000},"page":"e67480-e67480","source":"Crossref","is-referenced-by-count":0,"title":["Comparison Between Ultrasound and Magnetic Resonance Imaging Measurements of the Optic Nerve Sheath Diameter in Patients Undergoing Intracranial Surgery: Prospective Observational Single-Center Study"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4025-430X","authenticated-orcid":false,"given":"Mauricio","family":"Giraldo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1400-6756","authenticated-orcid":false,"given":"Luz Maria","family":"Lopera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9299-9178","authenticated-orcid":false,"given":"Aly","family":"Balbaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7178-2212","authenticated-orcid":false,"given":"Nelson","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2783-3072","authenticated-orcid":false,"given":"Raffael Pereira","family":"Cezar Zamper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3692-1328","authenticated-orcid":false,"given":"Michael","family":"Mayich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7246-4531","authenticated-orcid":false,"given":"Mel","family":"Boulton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"R1","unstructured":"Byrne SF Green RL . Ultrasound of the Eye and Orbit. 2nd ed. Mosby; 2002. ISBN: 9780323012072"},{"issue":"4","key":"R2","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.2214\/AJR.04.1842","article-title":"Sonography of the eye","volume":"187","author":"Bedi","journal-title":"AJR Am J Roentgenol"},{"issue":"8","key":"R3","doi-asserted-by":"publisher","first-page":"466","DOI":"10.4103\/0972-5229.162465","article-title":"Correlation of measurement of optic nerve sheath diameter using ultrasound with magnetic resonance imaging","volume":"19","author":"Shirodkar","journal-title":"Indian J Crit Care Med"},{"issue":"7","key":"R4","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.7863\/ultra.34.7.1285","article-title":"Sonography of the optic nerve sheath diameter for detection of raised intracranial pressure compared to computed tomography: a systematic review and meta-analysis","volume":"34","author":"Ohle","journal-title":"J Ultrasound Med"},{"issue":"5","key":"R5","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/s0002-9394(14)73195-2","article-title":"Measurement and relationship of subarachnoid pressure of the optic nerve to intracranial pressures in fresh cadavers","volume":"116","author":"Liu","journal-title":"Am J Ophthalmol"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2015.10.001","article-title":"Pathogenesis of optic disc edema in raised intracranial pressure","volume":"50","author":"Hayreh","journal-title":"Prog Retin Eye Res"},{"issue":"10","key":"R7","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1136\/bjo.86.10.1109","article-title":"Measurement of optic nerve sheath diameter by ultrasound: a means of detecting acute raised intracranial pressure in hydrocephalus","volume":"86","author":"Newman","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"R8","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1007\/s12028-009-9250-8","article-title":"Reliability of optic nerve ultrasound for the evaluation of patients with spontaneous intracranial hemorrhage","volume":"11","author":"Moretti","journal-title":"Neurocrit Care"},{"issue":"8","key":"R9","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1007\/s00134-018-5305-7","article-title":"Optic nerve sheath diameter measured sonographically as non-invasive estimator of intracranial pressure: a systematic review and meta-analysis","volume":"44","author":"Robba","journal-title":"Intensive Care Med"},{"issue":"3","key":"R10","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1007\/s12028-011-9606-8","article-title":"Optic nerve ultrasound for the detection of raised intracranial pressure","volume":"15","author":"Rajajee","journal-title":"Neurocrit Care"},{"issue":"4","key":"R11","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.3171\/2018.11.JNS182077","article-title":"Optic nerve sheath diameter ultrasonography at admission as a predictor of intracranial hypertension in traumatic brain injured patients: a prospective observational study","volume":"132","author":"Robba","journal-title":"J Neurosurg"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/503645","article-title":"Variations in eyeball diameters of the healthy adults","volume":"2014","author":"Bekerman","journal-title":"J Ophthalmol"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-59436-7_25","article-title":"Variability of the optic nerve sheath diameter on the basis of sex and age in a cohort of healthy volunteers","volume":"131","author":"Chandrapatham","journal-title":"Acta Neurochir Suppl"},{"issue":"3","key":"R14","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13030535","article-title":"Optic nerve ultrasound evaluation in children: a review","volume":"13","author":"Abbinante","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"R15","doi-asserted-by":"publisher","DOI":"10.1186\/s40779-018-0189-y","article-title":"Military trainees can accurately measure optic nerve sheath diameter after a brief training session","volume":"5","author":"Betcher","journal-title":"Mil Med Res"},{"issue":"2","key":"R16","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1553-2712.2007.00031.x","article-title":"Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure","volume":"15","author":"Kimberly","journal-title":"Acad Emerg Med"},{"issue":"2","key":"R17","first-page":"151","volume":"30","author":"Shafiq","journal-title":"J Ayub Med Coll Abbottabad"},{"issue":"5","key":"R18","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1111\/jon.12906","article-title":"Optic nerve sheath diameter assessment by neurosonology: a review of methodologic discrepancies","volume":"31","author":"Stevens","journal-title":"J Neuroimaging"},{"issue":"1","key":"R19","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-023-03062-4","article-title":"Ultrasound measurement of optic nerve sheath diameter in a healthy adult Colombian population","volume":"23","author":"Trocha","journal-title":"BMC Neurol"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/j.inat.2025.102091","article-title":"Ultrasound measurement of optic nerve sheath diameter for intracranial pressure monitoring","volume":"41","author":"Jiang","journal-title":"Interdiscip Neurosurg"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.05.224","article-title":"Contemporary management of increased intraoperative intracranial pressure: evidence-based anesthetic and surgical review","volume":"129","author":"Desai","journal-title":"World Neurosurg"},{"issue":"10","key":"R22","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1007\/s00381-016-3068-4","article-title":"The relationship between transorbital ultrasound measurement of the optic nerve sheath diameter (ONSD) and invasively measured ICP in children.: Part II: age-related ONSD cut-off values and patency of the anterior fontanelle","volume":"32","author":"Padayachy","journal-title":"Childs Nerv Syst"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-13-187","article-title":"Reproducibility and accuracy of optic nerve sheath diameter assessment using ultrasound compared to magnetic resonance imaging","volume":"13","author":"B\u00e4uerle","journal-title":"BMC Neurol"},{"issue":"1","key":"R24","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00381-019-04266-1","article-title":"The relation of optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in pediatric neurosurgery practice - part I: correlations, age-dependency and cut-off values","volume":"36","author":"Kerscher","journal-title":"Childs Nerv Syst"},{"issue":"1","key":"R25","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/s00381-019-04336-4","article-title":"The relation of optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in pediatric neurosurgery practice - Part II: influence of wakefulness, method of ICP measurement, intra-individual ONSD-ICP correlation and changes after therapy","volume":"36","author":"Kerscher","journal-title":"Childs Nerv Syst"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2021.08.002","article-title":"Comparison of B-scan ultrasound and mri-based optic nerve sheath diameter (ONSD) measurements in children","volume":"124","author":"Kerscher","journal-title":"Pediatr Neurol"},{"issue":"4","key":"R27","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/j.annemergmed.2006.06.040","article-title":"Emergency department sonographic measurement of optic nerve sheath diameter to detect findings of increased intracranial pressure in adult head injury patients","volume":"49","author":"Tayal","journal-title":"Ann Emerg Med"},{"issue":"3","key":"R28","doi-asserted-by":"publisher","first-page":"78","DOI":"10.32629\/ameir.v2i3.2615","article-title":"Indirect measurement of perioperative intracranial pressure-eye and orbitary ultrasound utility","volume":"2","author":"Herrero","journal-title":"Advances in Medicine and Engineering Interdisciplinary Research"}],"container-title":["JMIR Perioperative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/periop.jmir.org\/2026\/1\/e67480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:27:54Z","timestamp":1785536874000},"score":1,"resource":{"primary":{"URL":"https:\/\/periop.jmir.org\/2026\/1\/e67480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,17]]},"references-count":28,"URL":"https:\/\/doi.org\/10.2196\/67480","relation":{},"ISSN":["2561-9128"],"issn-type":[{"value":"2561-9128","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,17]]},"article-number":"v9i4e67480"}}