{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:55:32Z","timestamp":1782845732326,"version":"3.54.5"},"reference-count":58,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Infodemiology"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Eosinophilia and hypereosinophilic syndrome (HES) are rare disorders grouped under the term hypereosinophilic disorders. They are diagnosed based on an increased number of eosinophils. They can also cause serious symptoms, including skin, lung, and gastrointestinal problems. These disorders are very rarely recognized due to their rarity and misdiagnosis.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study analyzes public interest in hypereosinophilic disorders using data on internet search volume in Germany between 2020 and 2023. Objectives include identifying frequently searched terms, evaluating temporal trends, analyzing seasonal patterns, evaluating geographic differences in search behavior, and identifying unmet information needs and frequently searched risk factors.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective analysis using Google Ads Keyword Planner gathered monthly search volume data for 12 German terms related to hypereosinophilic disorders. These terms were selected based on their medical relevance and common usage identified from medical literature. Data were analyzed descriptively, with trends, seasonal variations, and geographical distributions examined. Chi-square\n \n tests and correlation analysis assessed statistical significance.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 178 keywords were identified, resulting in a search volume of 1,745,540 queries. The top keyword was \u201ceosophile,\u201d a misspelling, followed by \u201ceosinophilia\u201d and \u201cHES.\u201d The main categories included \u201cEosinophilia,\u201d \u201cEosinophils,\u201d and \u201cChurg-Strauss syndrome.\u201d Temporal analysis showed seasonal growth in search volumes, peaking in January 2023, with higher interest during winter. Geographical analysis showed regional variations.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This research shows a growing public interest in eosinophilic diseases, reflected by a steadily increasing search volume over time. This is particularly evident in searches for basic definitions and diagnostic criteria, such as \u201ceosinophils\u201d or \u201csymptoms of eosinophilic diseases.\u201d This increase in search volume, which peaked in January 2023, indicates an increased interest in accurate and readily available information for rare conditions.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/69040","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:01:18Z","timestamp":1748278878000},"page":"e69040-e69040","source":"Crossref","is-referenced-by-count":0,"title":["Tracking Public Interest in Rare Diseases and Eosinophilic Disorders in Germany: Web Search 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