{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:57:05Z","timestamp":1790971025535,"version":"4.1.0"},"reference-count":31,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Form Res"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Scores and prediction models such as the mangled extremity severity score (MESS) for trauma and the Wound, Ischemia, and foot Infection (WIfI) classification for diabetic foot ulcers help in the decision-making process for amputation. However, these tools can be subjective as they depend on the experience of the medical staff applying them.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study aimed to assess the impact of temperature measurement using infrared thermal imaging in extremity salvage in patients at risk of limb amputation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We included 29 patients who sought a second opinion after an amputation recommendation. Infrared thermographic images were acquired to measure the temperature difference (\u0394T) between the injured and uninjured limbs. For patients with salvaged limbs, we provided clinical follow-up for up to 12 weeks.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Of the 29 patients enrolled in the study, 27 limbs were salvaged. Thermographic imaging allowed the distinction into two groups: the first group of 18 patients with mean \u0394T value of \u22123.6 \u00b0C (SD 1.99 \u00b0C) , and the second group of 9 patients with mean \u0394T of 3.36 \u00b0C (SD 2.71 \u00b0C). None of the patients in either group showed progression in \u0394T values within the first 5 days; at the twelfth week, \u0394T values approached 0 \u00b0C at wound closure. Of the two patients who required amputation, one showed an initial \u0394T of \u22124.3 \u00b0C, which worsened to \u22125 \u00b0C by the fifth day, and the other patient showed an initial \u0394T of \u22124.5 \u00b0C, which worsened to \u22125.8 \u00b0C by the fifth day.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Digital infrared thermography is a tool that may help guide limb salvage in patients with uncertain clinical diagnoses. This imaging modality allows visualization of thermal differences and patterns derived from thermal changes in patients at risk of limb amputation.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/69072","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T04:54:06Z","timestamp":1747716846000},"page":"e69072-e69072","source":"Crossref","is-referenced-by-count":3,"title":["Digital Infrared Thermographic Imaging for Limb Salvage in Patients at Risk of Amputation: Prospective Observational Study"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2753-7935","authenticated-orcid":false,"given":"V\u00edctor Manuel","family":"Loza-Gonz\u00e1lez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7583-8655","authenticated-orcid":false,"given":"Eleazar 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