{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T17:30:55Z","timestamp":1791480655575,"version":"4.3.4"},"reference-count":70,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Neurotech"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n A 12-month longitudinal observational study was conducted on 43 children aged 2\u201018 years to evaluate the effectiveness of the CognitiveBotics artificial intelligence (AI)\u2013based platform in conjunction with continuous therapy in improving therapeutic outcomes for children with autism spectrum disorder (ASD).<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study evaluates the CognitiveBotics software\u2019s effectiveness in supporting children with ASD through structured, technology-assisted learning. The primary objectives include assessing user engagement, tracking progress, and measuring efficacy using standardized clinical assessments.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A 12-month observational study was conducted on children diagnosed with ASD using the CognitiveBotics AI-based platform. Standardized assessments, include the Childhood Autism Rating Scale (CARS), Vineland Social Maturity Scale, Developmental Screening Test, and Receptive Expressive Emergent Language Test (REEL), were conducted at baseline (T1) and at the endpoint (T2). All participants meeting the inclusion criteria were provided access to the platform and received standard therapy. Participants who consistently adhered to platform use as per the study protocol were classified as the intervention group, while those who did not maintain continuous platform use were designated as the control group. Additionally, caregivers received structured training, including web-based parent teaching sessions, reinforcement strategy training, and home-based activity guidance.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Participants in the intervention group demonstrated statistically significant improvements across multiple scales. CARS scores reduced from 33.41 (SD 1.89) at T1 to 28.34 (SD 3.80) at T2 (\n P<\/jats:italic>\n <.001). Social age increased from 22.80 (SD 7.33) to 35.76 (SD 9.09; mean change: 12.96, 56.84% increase;\n P<\/jats:italic>\n <.001). Social quotient increased from 53.26 (SD 11.84) to 64.75 (SD 16.12; mean change: 11.49, 21.57% increase;\n P<\/jats:italic>\n <.001). Developmental age showed an improvement from 30.93 (SD 9.91) to 45.31 (SD 11.20; mean change: 14.38, 46.49% increase;\n P<\/jats:italic>\n <.001), while developmental quotient increased from 70.94 (SD 10.95) to 81.33 (SD 16.85; mean change: 10.39, 14.65% increase;\n P<\/jats:italic>\n <.001). REEL scores showed substantial improvements, with receptive language increasing by 56.22% (\n P<\/jats:italic>\n <.001) and expressive language by 59.93% (\n P<\/jats:italic>\n <.001). In the control group, while most psychometric parameters showed some improvements, they were not statistically significant. CARS scores decreased by 10.62% (\n P<\/jats:italic>\n =.06), social age increased by 52.27% (\n P<\/jats:italic>\n =.06), social quotient increased by 19.62% (\n P<\/jats:italic>\n =.12), developmental age increased by 44.88% (\n P<\/jats:italic>\n =.06), and developmental quotient increased by 11.23% (\n P<\/jats:italic>\n =.19). REEL receptive and expressive language increased by 34.69% (\n P<\/jats:italic>\n =.10) and 40.48% (\n P<\/jats:italic>\n =.054), respectively.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Overall, the platform was an effective supplement in enhancing therapeutic outcomes for children with ASD. This platform holds promise as a valuable tool for augmenting ASD therapies across cognitive, social, and developmental domains. Future development should prioritize expanding the product\u2019s accessibility across various languages, ensuring cultural sensitivity and enhancing user-friendliness.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/70589","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T05:45:48Z","timestamp":1742535948000},"page":"e70589-e70589","source":"Crossref","is-referenced-by-count":16,"title":["Effectiveness of Artificial Intelligence\u2013Based Platform in Administering Therapies for Children With Autism Spectrum Disorder: 12-Month Observational Study"],"prefix":"10.2196","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2007-2679","authenticated-orcid":false,"given":"Harini","family":"Atturu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7876-7119","authenticated-orcid":false,"given":"Somasekhar","family":"Naraganti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0773-2817","authenticated-orcid":false,"given":"Bugatha Rajvir","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. 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