{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:57:48Z","timestamp":1782845868379,"version":"3.54.5"},"reference-count":74,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Public Health Surveill"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The 2003 outbreak of severe acute respiratory syndrome (SARS), caused by a novel coronavirus, heavily impacted Taiwan\u2019s health care system, triggering clinical crises and lasting effects among affected individuals and families. The first case in Taiwan was identified on February 25, 2003, and the final case was reported on June 15, 2003. During the epidemic, 346 people were diagnosed with SARS, leading to 37 deaths. Outbreaks also occurred in China, Singapore, and Toronto (Canada), showing the vulnerability of global health systems to new zoonotic diseases. Clinically, SARS causes high fever and severe lung inflammation. Survivors often had long-term lung problems, including fibrosis, and bone issues like osteonecrosis, mostly due to high-dose steroid treatment. Although studies have looked at long-term outcomes\u2014especially lung and bone issues\u2014none followed patients beyond 7 years. The COVID-19 pandemic further revealed gaps in understanding how serious viral infections affect wider health areas, including unintentional and intentional injuries. Data on related hospitalizations also remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to investigate the long-term risk of both unintentional and intentional injuries among survivors of SARS and their relatives, using a nationwide population-based cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study used data from Taiwan\u2019s National Health Insurance Research Database, focused on 285 individuals diagnosed with SARS in 2003 and 699 of their relatives, matched in a 1:10 ratio with controls. Injury risks were assessed using Fine and Gray\u2019s competing risk models, adjusting for sociodemographic and clinical covariates, over a follow-up period of up to 15 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Survivors of SARS exhibited a significant increase in the risk of accidental injuries, with an adjusted hazard ratio (AHR) of 1.631 (95% CI 1.184-2.011;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001), indicating persistent physiological vulnerabilities postinfection. Family members of survivors of SARS also had elevated injury risk (AHR 1.572, 95% CI 1.148-1.927;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001), possibly due to stress and caregiving burdens. Subgroup analysis showed increased risks for poisoning (AHR 2.701, 95% CI 1.956-4.084;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001) and falls (AHR 1.524, 95% CI 1.102-1.878;\n                      <jats:italic>P<\/jats:italic>\n                      =.003) among survivors. Relatives faced higher risks for traffic incidents (AHR 2.003, 95% CI 1.462-2.459), poisoning (AHR 1.531, 95% CI 1.120-1.886), medical incidents, falls (AHR 1.802, 95% CI 1.324-2.214), and crushing injuries (AHR 2.469, 95% CI 1.803-3.026; all\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001). These findings highlight the need for targeted preventive measures to address long-term health risks in both survivors of SARS and their families.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Survivors of SARS and their relatives face increased injury risks, highlighting long-term physical and psychosocial vulnerabilities after severe infectious outbreaks. These findings suggest that health care systems should provide preventive and supportive measures to mitigate long-term impacts for those affected by pandemics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/70608","type":"journal-article","created":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T08:15:06Z","timestamp":1749370506000},"page":"e70608-e70608","source":"Crossref","is-referenced-by-count":0,"title":["COVID-19\u2013Relevant Insights Into the Elevated Risk of Accidental Injuries in Survivors of SARS and Their Relatives in Taiwan: Retrospective Cohort Study"],"prefix":"10.2196","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5759-137X","authenticated-orcid":false,"given":"Chieh","family":"Sung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4576-9900","authenticated-orcid":false,"given":"Chi-Hsiang","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9041-0537","authenticated-orcid":false,"given":"Chien-An","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2982-3732","authenticated-orcid":false,"given":"Chang-Huei","family":"Tsao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8406-4068","authenticated-orcid":false,"given":"Daphne Yih","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5730-5679","authenticated-orcid":false,"given":"Tsu-Hsuan","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9800-3987","authenticated-orcid":false,"given":"Li-Yun","family":"Fann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9878-9625","authenticated-orcid":false,"given":"Fu-Huang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3286-0780","authenticated-orcid":false,"given":"Wu-Chien","family":"Chien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"issue":"9773","key":"R1","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1016\/S0140-6736(10)61459-6","article-title":"Viral pneumonia","volume":"377","author":"Ruuskanen","journal-title":"Lancet"},{"issue":"11","key":"R2","first-page":"73","volume":"78","journal-title":"Wkly Epidemiol Rec"},{"issue":"2","key":"R3","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1002\/gps.1432","article-title":"Elderly suicide and the 2003 SARS epidemic in Hong Kong","volume":"21","author":"Chan","journal-title":"Int J Geriatr Psychiatry"},{"issue":"12","key":"R4","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1002\/gps.2056","article-title":"A revisit on older adults suicides and severe acute respiratory syndrome (SARS) epidemic in Hong Kong","volume":"23","author":"Cheung","journal-title":"Int J Geriatr Psychiatry"},{"issue":"7","key":"R5","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1001\/jama.2020.13484","article-title":"Social isolation\u2014the other COVID-19 threat in nursing homes","volume":"324","author":"Abbasi","journal-title":"JAMA"},{"issue":"1","key":"R6","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S2213-2600(20)30407-0","article-title":"Beyond the clot: perfusion imaging of the pulmonary vasculature after COVID-19","volume":"9","author":"Dhawan","journal-title":"Lancet Respir Med"},{"issue":"1","key":"R7","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-020-01021-y","article-title":"What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? 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